Vertebroplasty in the Treatment of Pain in Osteoporotic Vertebral Compression Fractures
DOI:
https://doi.org/10.15225/PNN.2025.14.4.5Keywords
osteoporosis, post-fracture pain, vertebral fracture, vertebroplastyAbstract
Introduction. Osteoporosis is a metabolic disorder found in 1/3 of women and 1/8 of men over the age of 50. Increased bone fragility leads to low-energy fractures, 50% of them affect the vertebral bodies of the thoracic and lumbar spine. Fractures produce intensive pain which practically immobilize patients and require strong pain killers taking.
Aim. We retrospectively evaluated the effectiveness of vertebroplasty in treating pain caused by fresh osteoporotic vertebral fractures.
Material and Methods. 270 patients, 206 women and 64 men were included. Mean age of women was 78, and in men 79 years. All patients had fresh vertebral fracture producing intensive pain. Pain intensity was measured using a 10 cm Visual Analog Scale. Pain intensity was assessed using the VAS scale before vertebroplasty and then 12 hours, 1 day and 30 days after the procedure. All surgical procedures were performed under local anaesthesia in an operating theatre using a two-plane X-ray machine.
Results. Significant reduction of pain was noted in almost all patients within 12 hours after procedure, and perfect result with pain reduction from 7–9 cm in VAS scale to 2–4 cm were noted in all follow-up exams. Only 1of 270 patients had not reported any improvement. No systemic or local complication of the procedure were noted.
Conclusions. Vertebroplasty quickly, efficiently and for a longer period of time significantly reduces pain caused by osteoporotic vertebral fractures and should be considered as one of the primary method of treatment of pain caused by osteoporotic vertebral fracture. (JNNN 2025;14(4):178–181)
References
[1] Compston J., Cooper A., Cooper C. et al. UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos. 2017;12(1):43.
[2] Janiszewska M., Kulik T., Dziedzic M., Żołnierczuk-Kieliszek D., Barańska A. Osteoporoza jako problem społeczny — patogeneza, objawy i czynniki ryzyka osteoporozy pomenopauzalnej. Probl Hig Epidemiol. 2015;96(1):106–114.
[3] Anam A.K., Insogna K. Update on Osteoporosis Screening and Management. Med Clin North Am. 2021;105(6):1117–1134.
[4] Alsoof D., Anderson G., McDonald C.L., Basques B., Kuris E., Daniels A.H. Diagnosis and Management of Vertebral Compression Fracture. Am J Med. 2022;135(7):815–821.
[5] Musich S., Wang S.S., Schaeffer J.A., Slindee L., Kraemer S., Yeh C.S. Safety Events Associated with Tramadol Use Among Older Adults with Osteoarthritis. Popul Health Manag. 2021;24(1):122–132.
[6] Fajar P., Indah L.H. The Dangerous Effects of Tramadol Abuse: Literature Review. Jurnal Eduhealt. 2022;13(2):595–601.
[7] Akbar A., Zaheer A., Kharal M.M. et al. Evolving strategies for osteoporosis management in postmenopausal women: From tradition to innovation. Medicine (Baltimore). 2025;104(7):e41605.
[8] Valenzuela-Martínez S., Ramírez-Expósito M.J., Carrera-González M.P., Martínez-Martos J.M. Physiopathology of Osteoporosis: Nursing Involvement and Management. Biomedicines. 2023;11(4):1220.
[9] Saracen A., Kotwica Z. Complications of percutaneous vertebroplasty: An analysis of 1100 procedures performed in 616 patients. Medicine (Baltimore). 2016;95(24):e3850.
[10] Saracen A., Kotwica Z. Treatment of multiple osteoporotic vertebral compression fractures by percutaneous cement augmentation. Int Orthop. 2014;38(11):2309–2312.
[11] Głuszko P., Sewerynek E., Misiorowski W. et al. Guidelines for the diagnosis and management of osteoporosis in Poland. Update 2022. Endokrynol Pol. 2023;74(1):5–15.
[12] Zhao S., Lin Y., Lin Y., Li R., Chen D., Liang D. Effect of zoledronic acid on recurrent vertebral fractures after percutaneous vertebroplasty. J Orthop. 2025;72:275–283.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Agnieszka Saracen, Zbigniew Kotwica

This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Stats
Number of views and downloads: 74
Number of citations: 0