Influence of fat-free, fat and sucrose diets on rat periodont condition
Keywordsnutrition, periodontium, inflammation, antioxidant protection
Aim. To investigate the effect of consumption of diets with different content of fat and sugar on the state of the periodontium of rats.
Methods. The rats received a semi-synthetic fat-free diet (FFD), a fat diet (5 % sunflower oil), and a sucrose diet (50 % sucrose) for 30 days. Determined the degree of periodontal atrophy, tooth decay and in the gum homogenate - the activity of elastase, catalase, urease, lysozyme and the content of malondialdehyde (MDA).
Results. Sugar diet increases the degree of periodontal atrophy and tooth decay, but decreases elastase activity in the gums and increases catalase activity. Fat diet does not affect periodontal atrophy and tooth decay, but it reduces catalase activity.
Conclusion. The increase in the intensity of caries and periodontal atrophy under the influence of a sucrose diet is probably due to the stimulation of the formation of lactic acid. Fat nutrition does not affect the intensity of dental caries and the degree of periodontal atrophy.
Levitsky AP. Alimentary factors in the pathogenesis, prevention and treatment of dental diseases. Dentistry Bulletin. 2005;2:5-7. (in Russian)
Markov AV. Influence of high-fat diets with different fatty acid composition on rat periodontal condition. Journal Education, Health and Sport. 2017;7(1):846-856.
Levitsky AP, Makarenko OA, Selivanskaya IA [and others]. The application of high olein sunflower oil “Olivka” for the prevention of noninfectious diseases: the guidelines. Оdеssа, KP OGT, 2016:16. (in Russian)
Levitskу AP, Denga OV, Ivanov VS [and others]. The experimental stomatology. P. I. The experimental models of stomatological diseases. Odessa, KP OGT, 2017:59-67. (in Russian)
Levitsky AP, Makarenko OA, Demyanenko SA. Methods of experimental dentistry (teaching aid). Simferopol, Tarpan, 2018:78. (in Russian)
Levitsky AP, Makarenko OA, Selivanskaya IA. [and others]. Enzymatic methods for determination of oral dysbiosis for screening pro- and prebiotics: method guidelines. Кiev, GFC, 2007:22. (in Russian)
Shnayder SA, Levitsky AP. The experimental stomatology. P. I. The experimental models of stomatological diseases. Odessa, KP OGT, 2017:168. (in Russian)
Truhacheva NV. Mathematical Statistics in biomedical research using application package Statistica. Moskow, GJeOTAR-Media, 2012:379. (in Russian)
Gozhenko A. I., Levitsky A. P., Stepan V. T., Pustovoit I. P., Badiuk N. S., Maslyukov A. K. Advantages of high olein sunflower oil over palm oil according to biochemical research results / - PhOL – PharmacologyOnLine - N 2. - P. 293-301. https://pharmacologyonline.silae.it/files/archives/2020/vol2/PhOL_2020_2_A028_Gozhenko.pdf
Levitsky A. P., Egorov B. V., Gozhenko A. I., Badiuk N.S., Selivanskaya I. A., Lapinskaya A. P. Influence of high-fat nutrition with different fat-acid composition of fats on lipid peroxidation processes in rat's organs and tissues / PharmacologyOnLine; Archives - 2021 - vol.1. – P. 37-46. https://pharmacologyonline.silae.it/files/archives/2021/vol1/PhOL_2021_1_A006_Levitsky.pdf
How to Cite
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Number of views and downloads: 215
Number of citations: 0