The bitter side of high fructose corn syrup (HFCS) - the global obesity pandemic

Dagna Siedlecka, Wojciech Micał, Ewa Krzewicka-Romaniuk, Artur Romaniuk



Sweet taste accompanies our lives since childhood. Sugar is commonly used in industrial production. Increased consumption of simple sugars has been observed since many years. Sugars come in different forms and one of them - glucose-fructose is on scientists aim because if it's impact on health. Fructose has unique metabolic features, that could be harmful for human organism. Excessive consumption of this substance contributes to obesity pandemic, development of diabetes mellitus and cardiovascular disease. Obesity affects in particular children and teenagers.[1] High consumption of fructose disturb sense of hunger and satiety.


high fructose corn syrup; fructose; HFCS; syrup; sweetener; obesity

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Forshee RA, Anderson PA, Storey ML. Sugar-sweetened beverages and body mass index in children and adolescents: a meta-analysis. Am J Clin Nutr. 2008 Jun;87(6):1662–71.

Stanhope KL, Medici V, Bremer AA, et al. A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults. Am J Clin Nutr. 2015 Jun;101(6):1144–54.

Schwartz MW, Baskin DG, Kaiyala KJ, Woods SC. Model for the regulation of energy balance and adiposity by the central nervous system. Am J Clin Nutr. 1999 Apr;69(4):584–96.

Popkin BM, Armstrong LE, Bray GM, et al. A new proposed guidance system for beverage consumption in the United States. Am J Clin Nutr. 2006 Mar;83(3):529–42.

Malik VS, Popkin BM, Bray GA, et al. Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation. 2010 Mar 23;121(11):1356–64.

de Koning L, Malik VS, Kellogg MD, et al. Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men. Circulation. 2012 Apr 10;125(14):1735–41, S1.

Trumbo PR, Rivers CR. Systematic review of the evidence for an association between sugar-sweetened beverage consumption and risk of obesity. Nutr Rev. 2014 Sep;72(9):566–74.

Johnson RJ, Segal MS, Sautin Y, et al. Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am J Clin Nutr. 2007 Oct;86(4):899–906.

Sadowska J, Rygielska M. Technological and health aspects of using high fructose syrup in food production. Available from:,%203(94)/02_Sadowska.pdf

Gajewski P, Augustynowicz-Kopeć E, Wydawnictwo Medycyna Praktyczna. Interna Szczeklika: podręcznik chorób wewnętrznych 2013. Kraków: Medycyna Praktyczna; 2013.

Ludwig DS, Peterson KE, Gortmaker SL. Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. Lancet Lond Engl. 2001 Feb 17;357(9255):505–8.

Kosova EC, Auinger P, Bremer AA. The relationships between sugar-sweetened beverage intake and cardiometabolic markers in young children. J Acad Nutr Diet. 2013 Feb;113(2):219–27.

Ambrosini GL, Oddy WH, Huang RC, et al. Prospective associations between sugar-sweetened beverage intakes and cardiometabolic risk factors in adolescents. Am J Clin Nutr. 2013 Aug;98(2):327–34.

Bremer AA, Byrd RS, Auinger P. Differences in male and female adolescents from various racial groups in the relationship between insulin resistance-associated parameters with sugar-sweetened beverage intake and physical activity levels. Clin Pediatr (Phila). 2010 Dec;49(12):1134–42.

Bermudez OI, Gao X. Greater consumption of sweetened beverages and added sugars is associated with obesity among US young adults. Ann Nutr Metab. 2010;57(3–4):211–8.

Dhingra R, Sullivan L, Jacques PF, et al. Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation. 2007 Jul 31;116(5):480–8.

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Journal of Education, Health and Sport formerly Journal of Health Sciences

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