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Journal of Education, Health and Sport

The treatment of diabetes with new generation drugs
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The treatment of diabetes with new generation drugs

Authors

  • Szymon Jan Marosz Chair and Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin https://orcid.org/0000-0003-4774-8449
  • Aleksnadra Joanna Borkowska Chair and Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin https://orcid.org/0000-0002-0950-2176
  • Paulina Mikulska Mazovian Regional Hospital of St. John Paul II in Siedlce Sp. z o.o. https://orcid.org/0000-0003-0876-6150
  • Katarzyna Borkowska Mazovian Regional Hospital of St. John Paul II in Siedlce Sp. z o.o. https://orcid.org/0000-0002-2090-7887
  • Jolanta Kowieska Mazovian Regional Hospital of St. John Paul II in Siedlce Sp. z o.o. https://orcid.org/0000-0001-5257-686X

DOI:

https://doi.org/10.12775/JEHS.2020.10.09.083

Keywords

diabetes, GLP-1 analogues, SGLT-2 inhibitors

Abstract

Introduction: Diabetes is a global problem, affecting nearly 422 million people around the world. Pathogenesis includes a defect in secretion or insulin activity. This results in an increase in the glucose level, which is associated with the development of complications. These include changes in peripheral vessels and nerves that lead to their damage. It is necessary to introduce appropriate treatment in the earliest stages of the disease to prevent these effects.

Materials and methods: The aim of this work is to present knowledge about the treatment based on the recommendations of the Polish Diabetes Association, American Diabetes Association, as well as a literature review and analysis of publications published on PubMed and Google Scholar platforms.

Results: Over the years, the recommendations and recommendations for treatment change. Recently, a greater role has been given to the latest antidiabetic drugs. This group includes SGLT-2 inhibitors as well as incremental drugs, the main representatives of which are GLP-1 analogues. These drugs affect the level of glycemia, but also have a beneficial effect on weight reduction and reduce the risk of cardiovascular events. Recently, Poland has introduced reimbursement of some new generation antidiabetic drugs such as dapaglyphosin, empaglyphosin and canaglyphosin.

Conclusions: Dynamic development of diabetes treatment helps to slow down the course of the disease and postpones the introduction of insulin therapy as the final treatment method. Reimbursement of some antidiabetic drugs enables patients to have better access to drugs that have not been within their reach so far. The changes introduced are, in a way, groundbreaking in the treatment of diabetes.

 

References

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Piotr Gajewski, Andrzej Szczeklik (2019) Interna Szczeklika 2019

Diabetologia po dyplomie 2017(01) „Co to jest cukrzyca?” Dr n. med. Irmina Korzeniewska-Dyl

American Diabetes Association. Standards of Medical care in diabetes 2020 , The Journal of CliniCal and applied researCh and eduCaTion Volume 43 |supplement

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Obwieszczenia ministra zdrowia - lista leków refundowanych (marzec 2020)

Czupryniak L.: Leczenie cukrzycy w roku 2020 – coraz silniejsza pozycja i coraz większa dostępność nowych leków przeciwcukrzycowych. Nowości w zaleceniach klinicznych Polskiego Towarzystwa Diabetologicznego oraz stanowisku American Diabetes Association i European Association for the Study of Diabetes. Med. Prakt., 2020; 3: 42–53

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Published

2020-09-24

How to Cite

1.
MAROSZ, Szymon Jan, BORKOWSKA, Aleksnadra Joanna, MIKULSKA, Paulina, BORKOWSKA, Katarzyna and KOWIESKA, Jolanta. The treatment of diabetes with new generation drugs. Journal of Education, Health and Sport. Online. 24 September 2020. Vol. 10, no. 9, pp. 690-696. [Accessed 5 July 2025]. DOI 10.12775/JEHS.2020.10.09.083.
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Vol. 10 No. 9 (2020)

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