Dry socket - clinical procedures review

Hubert Nieścior, Damian Bator, Magdalena Wójcik, Julita Szarpak, Justyna Dąbrowska, Dominika Sereda

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.09.025


Introduction: Dry socket is a complication following extraction surgery. It usually appears between days 1 and 3 after extraction. The partially disorganized clot breaks down and healing is impaired.

Material and methods: The latest reports available on the dry socket and its treatment using various methods were used. The NCBI database was used for this purpose, using the terms "dry socket" and "dry socket treatment".

State of knowledge: Dry socket occurs as a complication in 1-5% of extraction sockets, while in the case of sockets after 3 mandibular molars, the percentage is as high as 38%. Risk factors may include: insufficient blood supply to the tissue, use of an excessive amount of anesthetic, hormonal contraception, smoking, traumatic surgery, failure to follow the doctor's instructions regarding the postoperative procedure. Chlorhexidine, warm saline, platelet plasma, hyaluronic acid-impregnated collagen sponges, resorbable collagen membranes and eugenol with lidocaine on Penghawar Djambi carrier can be used to treat dry socket.

Summary: Dry socket is a medical condition. The unification of treatment recommendations is the goal of research on tools used in the context of a dry socket. Evaluation of profits and losses will allow to unify the recommendations and reduce the incidence of this complication.


Dry socket

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Blum IR. Contemporary views on dry socket (alveolar osteitis): A clinical appraisal of standardization, aetiopathogenesis and management: A critical review. Int J Oral Maxillofac Surg. 2002;31:309-17.

Gottlieb B, Crawford H. Therapy and prophylaxis of dry socket. Am J Orthod Oral Surg. 1943;29:B328–31.

Cardoso CL, Rodrigues MTV, Ferreira Júnior O, Garlet GP, de Carvalho PSP. Clinical concepts of dry socket. J Oral Maxillofac Surg. 2010;68:1922-32.

Burgoyne CC, Giglio JA, Reese SE, Sima AP, Laskin DM. The efficacy of a topical anesthetic gel in the relief of pain associated with localized alveolar osteitis. J Oral Maxillofac Surg. 2010;68:144-8.

Bowe DC, Rogers S, Stassen LF. The management of dry socket/ alveolar osteitis. J Ir Dent Assoc 2011-2012;57:305-10.

Larsen PE. Alveolar osteitis after surgical removal of impacted mandibular third molars. Identification of the patient at risk. Oral Surg Oral Med Oral Pathol. 1992;73:393–97.

Fotos PG, Koorbusch GF, Sarasin DS, Kist RJ. Evaluation of intra-alveolar chlorhexidine dressings after removal of impacted mandibular third molars. Oral Surg Oral Med Oral Pathol. 1992;73:383–88.

Hermesch CB, Hilton TJ, Biesbrock AR, Baker RA, Cain-Hamlin J, McClanahan SF. Perioperative use of 0.12% chlorhexidine gluconate for the prevention of alveolar osteitis: efficacy and risk factor analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85:381–87.

Hamasha AA, Al-Khateeb T, Darwazeh A. Prevalence of dilaceration in Jordanian adults. Int Endod J 2002;35:910-2.

Eshghpour M, Nejat AH. Dry socket following surgical.

removal of impacted third molars in an Iranian population: Incidence and risk factors. Niger J Clin Pract. 2013;16:496-500.

Oginni FO. Dry socket: A prospective study of prevalent risk factors in a Nigerian population. J Oral Maxillofac Surg. 2008;66:2290-5.

Taberner-Vallverdú M, Sánchez-Garcés MÁ, Gay-Escoda C. Efficacy of different methods used for dry socket prevention and risk factor analysis: A systematic review. Med Oral Patol Oral Cir Bucal. 2017;22(6):e750-e758.

Ren YF, Malmstrom HS. Effectiveness of antibiotic prophylaxis in third molar surgery: A meta-analysis of randomized controlled clinical trials. J Oral Maxillofac Surg. 2007;65:1909-21.

Arteagoitia MI, Barbier L, Santamaría J, Santamaría G, Ramos E. Efficacy of amoxicillin and amoxicillin/clavulanic acid in the prevention of infection and dry socket after third molar extraction. A systematic review and meta-analysis. Med Oral Patol Oral Cir Bucal. 2016;21(4):e494-e504.

Iglesias-Martín F, García-Perla-García A, Yañez-Vico R, Aced-Jiménez E, Arjona-Gerveno E, González-Padilla JD. Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars. Med Oral Patol Oral Cir Bucal. 2014;19:e612–5.

Oomens MA, Forouzanfar T. Antibiotic prophylaxis in third molar surgery: a review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114:e5–12.

Lodi G, Figini L, Sardella A, Carrassi A, Del Fabbro M, Furness S. Antibiotics to prevent complications following tooth extractions. Cochrane Database Syst Rev. 2012;11:CD003811

Piecuch J.F., Arzadon J., and Lieblich S.E.: Prophylactic antibiotics for third molar surgery: A supportive opinion. J Oral Maxillofac Surg 1995; 53: pp. 53

Haraji A, Rakhshan V. Clorhexidine gel and less difficult surgeries might reduce post-operative pain, controlling for dry socket infection and analgesic consumption: A split-mouth controlled randomised clinical trial. J Oral Rehabil. 2015;42:209-19.

Rodríguez-Pérez M, Bravo-Pérez M, Sánchez-López JD, MuñozSoto E, Romero-Olid MN, Baca-García P. Effectiveness of 1% versus 0.2% clorhexidine gels in reducing alveolar osteitis from mandibular third molar surgery: A randomized, double-blind clinical trial. Med Oral Patol Oral Cir Bucal. 2013;18:693-700.

Minguez-Serra MP, Salort-Llorca C, Silvestre-Donat FJ. Clorhexidine in the prevention of dry socket: Effectiveness of different dosage forms and regimens. Med Oral Patol Oral Cir Bucal. 2009;14:e445-9.

Nazaroglou I, Stavrianos C, Kafas P, Matoulas E, Upile T, Barlas I . Radiographic evaluation of bone regeneration after the application of plasma rich in growth factors in a lower third molar socket: a case report. Cases J. 2009;2:9134.

Samandari MH, Haghighat A, Torabinia N, Taghian M, Sadri L, Naemy V. Socket preservation using freeze-dried bone allograft with and without plasma rich in growth factors in dogs. Dent Res J (Isfahan) 2016;13:432–39.

Taschieri S, Corbella S, Del FM. Use of plasma rich in growth factor for schneiderian membrane management during maxillary sinus augmentation procedure. J Oral Implantol. 2012;38:621–27.

Xu JL, Xia R. Efficacy of plasma rich in growth factor used for dry socket management: a systematic review. Med Oral Patol Oral Cir Bucal. 2019;24(6):e704-e711.

Xiang X, Shi P, Zhang P, Shen J, Kang J. Impact of platelet-rich fibrin on mandibular third molar surgery recovery: a systematic review and meta-analysis. BMC Oral Health. 2019;19(1):163.

Osunde OD, Anyanechi CE, Bassey GO. Prevention of alveolar osteitis after third molar surgery: Comparative study of the effect of warm saline and chlorhexidine mouth rinses. Niger J Clin Pract. 2017;20(4):470-473.

Osunde OD, Adebola RA, Adeoye JB, Bassey GO. Comparative study of the effect of warm saline mouth rinse on complications after dental extractions. Int J Oral Maxillofac Surg 2014;43:649-53.

Alling CC, Helfric JF, Alling RD. Impacted Teeth. 1993.

Delilbasi C, Saracoglu U, Keskin A. Effects of 0.2% chlorhexidine gluconate and amoxicillin plus clavulanic acid on the prevention of alveolar osteitis following mandibular third molar extractions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:301-4.

Matou-Nasri S., Gaffney J., Kumar S., Slevin M. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and γ-adducin. Int. J. Oncol. 2009;35:761–773.

Chen W.J., Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen. 1999;7:79–89.

Suchánek J, Ivančaková RK, Mottl R, et al. Hyaluronic Acid-Based Medical Device for Treatment of Alveolar Osteitis-Clinical Study. Int J Environ Res Public Health. 2019;16(19):3698. Published 2019 Oct 1.

Kilinc A, Ataol M. How effective is collagen resorbable membrane placement after partially impacted mandibular third molar surgery on postoperative morbidity? A prospective randomized comparative study. BMC Oral Health. 2017;17(1):126. Published 2017 Oct 5.

Bunyaratavej P, Wang HL. Collagen membranes: a review. J Periodontol. 2001;72:215–29.

Jesudasan JS, Wahab PU, Sekhar MR. Effectiveness of 0.2% clorhexidine gel and an eugenol-based paste on postoperative alveolar osteítis in patients having third molars extracted: A randomised controlled clinical trial. Br J Oral Maxillofac Surg. 2015;53:826-30.

Summers, L.; Matz, L.R. Extraction wound sockets. Histological changes and paste packs—A trial. Br. Dent. J. 1976, 141, 377–379.

Longaker M.T., Chiu E.S., Adzick N.S., Stern M., Harrison M.R., Stern R. Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid. Ann. Surg. 1991;213:292–296.

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Journal of Education, Health and Sport formerly Journal of Health Sciences

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