The effect of vitamin D on mental health – literature analysis

Magdalena Kozyra, Patryk Zimnicki, Justyna Kaczerska, Natalia Śmiech, Martyna Nowińska, Joanna Milanowska

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.08.048

Abstract


Introduction: Many sources list a number of properties of vitamin D on human health. It seems that the benefits of using this vitamin include not only the regulation of the calcium-phosphate metabolism, but also a number of other applications, also in human mental health.

The aim of the study: The aim of the study was to research about the influence of vitamin D on the mental health. The research was done on the problems such as depression, anxiety, psychoses, stress, mood and emotions.

Material and method: The literature was found using websites such as PubMed or Google Scholar was used to develop this work.

Description of the state of knowledge: A number of studies have confirmed that vitamin D can have a significant impact on reducing the level of depression. One example of a study on this topic is that high vitamin D supplementation in women in early pregnancy can protect them from late depression during the last weeks of pregnancy. Likewise, adequate vitamin D supplementation in older people can improve mental health and reduce the likelihood of depression and Seasonal Mood Disorder (SAD). In addition, vitamin D can reduce the probability of psychosis or anxiety disorders.

Summary: Many sources report a positive correlation between vitamin D supply and mental health. Often the differences are also noticeable, but not statistically significant. This work sometimes shows divergent views of scientists, which is important to continue research into the effects of vitamin D on mental health in humans.


Keywords


vitamin D; anxiety; depression; psychoses; stress; mood

Full Text:

PDF

References


Holick M.F.: Vitamin D and bone health. J. Nutr. 1996; 126 (supl.): 1159S-1164S

Woźniacka A., Bogaczewicz J., Sysa-Jędrzejowska A.: Drugie oblicze słońca. Prawdziwy „D”ylemat. Część 1. Przegl. Dermatol. 2008; 95: 467-474

Haddad J.G., Matsuoka L.Y., Hollis B.W. i wsp.: Human plasma transport of vitamin D after its endogenous synthesis. J. Clin. Invest. 1993; 91: 2552-2555

Segaert S., Bouillon R.: Vitamin D and regulation of gene expression. Curr. Opin. Clin. Nutr. Metab. Care 1998; 1: 347-354.

NAS/DRI: Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. National Academy Press, Washington, D.C. 1997

Romer T.E.: Endokrynologia kliniczna dla ginekologa, internisty i pediatry. Springer PWN, Warszawa 1998.

Przybelski R.J., Binkley N.C.: Is vitamin D important for preserving cognition? A positive correlation of serum 25-hydroxyvitamin D concentration with cognitive function. Arch. Biochem. Biophys. 2007; 460: 202-205.

Bryan J., Osendarp S., Hughes D. i wsp.: Nutrients for cognitive development in school-aged children. Nutr. Rev. 2004; 62: 295-306.

McCann J.C., Ames B.N.: Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals. Am. J. Clin. Nutr. 2005; 82: 281-295.

McCann J.C., Hudes M., Ames B.N.: An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring. Neurosci. Biobehav. Rev. 2006; 30: 696-712.

McCann J.C., Ames B.N.: An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function. Am. J. Clin. Nutr. 2007; 85: 931-945.

Siega-Riz A.M., Popkin B.M.: Dietary trends among low socioeconomic status women of childbearing age in the United States from 1977 to 1996: a comparison among ethnic groups. J. Am. Med. Womens Assoc. 2001; 56: 44-48, 72.

Lee J.S., Frongillo E.A. Jr: Nutritional and health consequences are associated with food insecurity among U.S. elderly persons. J. Nutr. 2001; 131: 1503-1509.

Dixon L.B., Winkleby M.A., Radimer K.L.: Dietary intakes and serum nutrients differ between adults from food-insufficient and food-sufficient families: Third National Healthand Nutrition Examination

World Health Organization (WHO) (2017). Depression. Fact sheet. Available online at: http://www.who.int/mediacentre/factsheets/fs369/en/

Narbona J. Fenomenología depresiva al inicio de enfermedades neuropediátricas [Depressive phenomenology at the outset of neuropaediatric diseases]. Rev Neurol. 2014 Feb 24;58 Suppl 1:S71-5. Spanish. PMID: 25252671.

Bernaras E, Jaureguizar J, Garaigordobil M. Child and Adolescent Depression: A Review of Theories, Evaluation Instruments, Prevention Programs, and Treatments. Front Psychol. 2019 Mar 20;10:543. doi: 10.3389/fpsyg.2019.00543. PMID: 30949092; PMCID: PMC6435492.

Okereke OI, Singh A. The role of vitamin D in the prevention of late-life depression. J Affect Disord. 2016 Jul 1;198:1-14. doi: 10.1016/j.jad.2016.03.022. Epub 2016 Mar 9. PMID: 26998791; PMCID: PMC4844780.

Williams JA, Romero VC, Clinton CM, Vazquez DM, Marcus SM, Chilimigras JL, Hamilton SE, Allbaugh LJ, Vahratian AM, Schrader RM, Mozurkewich EL. Vitamin D levels and perinatal depressive symptoms in women at risk: a secondary analysis of the mothers, omega-3, and mental health study. BMC Pregnancy Childbirth. 2016 Aug 3;16(1):203. doi: 10.1186/s12884-016-0988-7. PMID: 27485050; PMCID: PMC4971719.

Zhu DM, Zhao W, Zhang B, Zhang Y, Yang Y, Zhang C, Wang Y, Zhu J, Yu Y. The Relationship Between Serum Concentration of Vitamin D, Total Intracranial Volume, and Severity of Depressive Symptoms in Patients With Major Depressive Disorder. Front Psychiatry. 2019 May 9;10:322. doi: 10.3389/fpsyt.2019.00322. PMID: 31143135; PMCID: PMC6520644.

Shaffer JA, Edmondson D, Wasson LT, Falzon L, Homma K, Ezeokoli N, Li P, Davidson KW. Vitamin D supplementation for depressive symptoms: a systematic review and meta-analysis of randomized controlled trials. Psychosom Med. 2014 Apr;76(3):190-6. doi: 10.1097/PSY.0000000000000044. PMID: 24632894; PMCID: PMC4008710.

Stefanis NC, Hanssen M, Smirnis NK, Avramopoulos DA, Evdokimidis IK, Stefanis CN, Verdoux H, Van Os J. Evidence that three dimensions of psychosis have a distribution in the general population. Psychol Med. 2002 Feb;32(2):347-58. doi: 10.1017/s0033291701005141. PMID: 11866327.

Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CM. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet. 2009 Jan 17;373(9659):234-9. doi: 10.1016/S0140-6736(09)60072-6. PMID: 19150704; PMCID: PMC3879718.

Hedelin M, Löf M, Olsson M, Lewander T, Nilsson B, Hultman CM, Weiderpass E. Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33,000 women from the general population. BMC Psychiatry. 2010 May 26;10:38. doi: 10.1186/1471-244X-10-38. PMID: 20504323; PMCID: PMC2889879.

Pilecka I, Sandin S, Reichenberg A, Scragg RKR, David A, Weiderpass E. Sun Exposure and Psychotic Experiences. Front Psychiatry. 2017 Jun 19;8:107. doi: 10.3389/fpsyt.2017.00107. PMID: 28674506; PMCID: PMC5474873.

Ji S, Wang L, Li L. Effect of Metformin on Short-Term High-Fat Diet-Induced Weight Gain and Anxiety-Like Behavior and the Gut Microbiota. Front Endocrinol (Lausanne). 2019 Oct 18;10:704. doi: 10.3389

Salehi-Abargouei A, Esmaillzadeh A, Azadbakht L, Keshteli AH, Afshar H, Feizi A, Feinle-Bisset C, Adibi P. Do patterns of nutrient intake predict self-reported anxiety, depression and psychological distress in adults? SEPAHAN study. Clin Nutr. 2019 Apr;38(2):940-947. doi: 10.1016/j.clnu.2018.02.002.

Kelley L, Sanders AF, Beaton EA. Vitamin D deficiency, behavioral atypicality, anxiety and depression in children with chromosome 22q11.2 deletion syndrome. J Dev Orig Health Dis. 2016 Dec;7(6):616-625. doi: 10.1017/S2040174416000428. PMID: 27827293; PMCID: PMC5922262.

Han B, Zhu FX, Yu HF, Liu S, Zhou JL. Low serum levels of vitamin D are associated with anxiety in children and adolescents with dialysis. Sci Rep. 2018 Apr 13;8(1):5956. doi: 10.1038/s41598-018-24451-7. PMID: 29654252; PMCID: PMC5899084.

Huang JY, Arnold D, Qiu CF, Miller RS, Williams MA, Enquobahrie DA. Association of serum vitamin D with symptoms of depression and anxiety in early pregnancy. J Womens Health (Larchmt). 2014 Jul;23(7):588-95. doi: 10.1089/jwh.2013.4598. Epub 2014 Jun 11. PMID: 24918744; PMCID: PMC4089018.

Kim SY, Jeon SW, Lim WJ, Oh KS, Shin DW, Cho SJ, Park JH, Shin YC. The Relationship between Serum Vitamin D Levels, C-Reactive Protein, and Anxiety Symptoms. Psychiatry Investig. 2020 Apr;17(4):312-319. doi: 10.30773/pi.2019.0290. Epub 2020 Mar 27. PMID: 32213801; PMCID: PMC7176560.

Fazelian S, Amani R, Paknahad Z, Kheiri S, Khajehali L. Effect of Vitamin D Supplement on Mood Status and Inflammation in Vitamin D Deficient Type 2 Diabetic Women with Anxiety: A Randomized Clinical Trial. Int J Prev Med. 2019 Feb 12;10:17. doi: 10.4103/ijpvm.IJPVM_174_18. PMID: 30820304; PMCID: PMC6390422.

Ramadan R, Vaccarino V, Esteves F, Sheps DS, Bremner JD, Raggi P, Quyyumi AA. Association of vitamin D status with mental stress-induced myocardial ischemia in patients with coronary artery disease. Psychosom Med. 2014 Sep;76(7):569-75. doi: 10.1097/PSY.0000000000000088. PMID: 25222601; PMCID: PMC4166546.

Lansdowne AT, Provost SC. Vitamin D3 enhances mood in healthy subjects during winter. Psychopharmacology (Berl). 1998 Feb;135(4):319-23. doi: 10.1007/s002130050517. PMID: 9539254.

Choukri MA, Conner TS, Haszard JJ, Harper MJ, Houghton LA. Effect of vitamin D supplementation on depressive symptoms and psychological wellbeing in healthy adult women: a double-blind randomised controlled clinical trial. J Nutr Sci. 2018 Aug 23;7:e23. doi: 10.1017/jns.2018.14. PMID: 30197783; PMCID: PMC6123885.

Penckofer S, Byrn M, Adams W, Emanuele MA, Mumby P, Kouba J, Wallis DE. Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes. J Diabetes Res. 2017;2017:8232863. doi: 10.1155/2017/8232863. Epub 2017 Sep 7. PMID: 29082262; PMCID: PMC5610883.

Husmann C, Frank M, Schmidt B, Jöckel KH, Antel J, Reissner V, Libuda L, Hebebrand J, Föcker M. Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents. PLoS One. 2017 Aug 23;12(8):e0183091. doi: 10.1371/journal.pone.0183091. PMID: 28832616; PMCID: PMC5568331.

Dean AJ, Bellgrove MA, Hall T, Phan WM, Eyles DW, Kvaskoff D, McGrath JJ. Effects of vitamin D supplementation on cognitive and emotional functioning in young adults--a randomised controlled trial. PLoS One. 2011;6(11):e25966. doi: 10.1371/journal.pone.0025966. Epub 2011 Nov 4. PMID: 22073146; PMCID: PMC3208539.

Dumville J.C., Miles J.N., Porthouse J. i wsp.: Can vitamin D supplementation prevent winter-time blues? A randomised trial among older women. J. Nutr. Health Aging 2006; 10: 151-153.

Gloth F.M. 3rd, Alam W., Hollis B.: Vitamin D vs broad spectrum phototherapy in the treatment of seasonal affective disorder. J. Nutr. Health Aging 1999; 3: 5-7.

Hathcock JN, Shao A, Vieth R, Heaney R. Risk assessment for vitamin D. Am J Clin Nutr. 2007 Jan;85(1):6-18. doi: 10.1093/ajcn/85.1.6. PMID: 17209171.

Vieth R. Why the optimal requirement for Vitamin D3 is probably much higher than what is officially recommended for adults. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):575-9. doi: 10.1016/j.jsbmb.2004.03.038. PMID: 15225842.

Galior K, Grebe S, Singh R. Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports. Nutrients. 2018 Jul 24;10(8):953. doi: 10.3390/nu10080953. PMID: 30042334; PMCID: PMC6115827.


Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM




Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska, EuroPub database, NLM Catalog Result - NCBI, BASE, Russian Sciences Index, Arianta.

https://zdb-katalog.de/title.xhtml?idn=1080187162

https://europub.co.uk/journals/22625

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Publisher and Editorial Office
Department of Physical Culture,
Faculty of Earth Sciences and Spatial Management,
Nicolaus Copernicus University in Toruń, Poland
Address: Str. Lwowska 1, 87-100 Toruń, Poland

  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

RG Journal Impact: 0.18 *

*This value is calculated using ResearchGate data and is based on average citation counts from work published in this journal. The data used in the calculation may not be exhaustive.

RG Journal impact history

2020Available summer 2021
2018 / 20190.18
20170.07
20160.03

RG Journal impact over time

RG Journal impact
0.180.160.140.120.100.080.060.040.02201620172018
  

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)

Partnerzy platformy czasopism