Vegetative and endocrine predictors of individual immune responses to adaptogenic balneotherapy

Zoryana Struk, Oksana Mel’nyk, Walery Zukow, Igor Popovych

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.01.024

Abstract


Background. Earlier four variants of the immune responses to adaptogenic balneotherapy have been identified. All four variants of immune responses are virtually unmistakably predicted by a set of 20 predictors including 12 immune blood parameters and one saliva parameter, 4 information parameters, 2 fecal microbiota parameters as well as erythrocyturia. The purpose of this study is to search for predictors of immune responses among the registered parameters of the autonomic nervous and endocrine systems. Material and methods. The object of observation were 34 men and 10 women aged 24-70 years old, who came to the Truskavets’ spa for the treatment of chronic pyelonephritis combined with cholecystitis in remission. We determined them the HRV parameters and plasma levels of principal adaptation Hormones: Cortisol, Testosterone and Triiodothyronine. Results. Discriminant analysis revealed that constellation 8 HRV and 5 Endocrine parameters as well as Gender of the patient predicts the nature of the immune response with an accuracy of 90,9%. Conclusion. The previously revealed variety of immune responses to adaptogenic balneotherapy is quite strictly conditioned by the initial state of the neuroendocrine-immune complex and microbiota as well as the sex of patients.


Keywords


HRV; Cortisol; Testosterone and Triiodothyronine; Immunity.

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References


Baevskiy RM, Ivanov GG. Heart Rate Variability: theoretical aspects and possibilities of clinical application [in Russian]. Ultrazvukovaya i funktsionalnaya diagnostika. 2001; 3: 106-127.

Barylyak LG, Tsymbryla VV, Zukow W, Popovych IL. Relationships between parameters of plasma lipoproteines profile and heart rate variability. Journal of Education, Health and Sport. 2019; 9(12): 238-253.

Berntson GG, Bigger JT jr, Eckberg DL, Grossman P, Kaufman PG, Malik M, Nagaraja HN, Porges SW, Saul JP, Stone PH, Van der Molen MW. Heart Rate Variability: Origines, methods, and interpretive caveats. Psychophysiology. 1997; 34: 623-648.

Goryachkovskiy АМ. Clinical Biochemistry [in Russian]. Odesa: Astroprint; 1998: 608 p.

Gozhenko AI, Zukow W, Polovynko IS, Zajats LM, Yanchij RI, Portnichenko VI, Popovych IL. Individual Immune Responses to Chronic Stress and their Neuro-Endocrine Accompaniment. RSW. UMK. Radom. Torun; 2019: 200 p.

Heart Rate Variability. Standards of Measurement, Physiological Interpretation, and Clinical Use. Task Force of ESC and NASPE. Circulation. 1996; 93(5): 1043-1065.

Hrytsak YaL, Barylyak LG, Zukow W, Popovych IL. Cluster analysis of hormonal constellation at women and men with harmonious and disharmonious general adaptation reactions. Journal of Education, Health and Sport. 2016; 6(4): 141-150.

Klecka WR. Discriminant Analysis [trans. from English to Russian] (Seventh Printing, 1986). In: Factor, Discriminant and Cluster Analysis. Moskva: Finansy i Statistika; 1989: 78-138.

Mel’nyk OI, Struk ZD. Predictors of individual immune responses to adaptogens. Experimental and Clinical Physiology and Biochemistry. 2019; 88(4): 5-15.

Mel’nyk OI, Struk ZD, Zukow W, Popovych IL. Vegetative, endocrine and metabolic accompaniments of individual immune responses to adaptogenic balneotherapy. Journal of Education, Health and Sport. 2019; 9(12): 207-229.

Pavlov VA, Chavan SS, Tracey KJ. Molecular and functional neuroscience in immunity. Annu Rev Immunol. 2018; 36: 783-812.

Popadynets’ OO, Gozhenko AI, Zukow W, Popovych IL. Relationships between the entropies of EEG, HRV, immunocytogram and leukocytogram. Journal of Education, Health and Sport. 2019; 9(5): 651-666.

Sternberg EM. Neural regulation of innate immunity: a coordinated nonspecific response to pathogens. Nat Rev Immunol. 2006; 6(4): 318-328.

Struk ZD, Mel’nyk OI, Zukow W, Popovych IL. The diversity of immune reactions to balneotherapy and their accompaniments. Journal of Education, Health and Sport. 2019; 9(11): 349-373.

Struk ZD, Mel’nyk OI, Mysakovets’ OG. Individual immune responses to adaptogens and their predictors. In: Rehabilitation Medicine and Health-Resort Institutions Development. Proceedings of the 19th International Applied Research Conference (Kyїv, 11-12 December 2019). Edited by O. Gozhenko, W. Zukow. Toruń, Kyiv. 2019: 83-84.

Thayer JF, Sternberg EM. Neural aspects of immunomodulation: Focus on the vagus nerve. Brain Behav Immun. 2010; 24(8): 1223-1228.

Uchakin PN, Uchakina ON, Tobin BV, Yershov FI. Neuroendocrine Immunomodulation [in Russian]. Vestnik Ross AMN. 2007; 9: 26-32.


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