Dynamics of antioxidant-prooxidant balance in abdominal injury with underlying hypovolemic shock and reperfusion syndrom of the limbs in experiment

V. O. Krylyuk, V. K. Grodetskyi, O. V. Fedoseyeva, S. V. Garian

DOI: http://dx.doi.org/10.12775/JEHS.2020.10.01.013

Abstract


The article describes the results of the experimental study in which the effect of ischemic-reperfusion limb syndrome on changes in the internal organs was studied. Changes in the values of Malone dialdehalide, superoxide dismutase and catalase in the tissues of the kidneys, liver, lungs and muscles of the extremities were studied. These studies confirmed the hypothesis and proved the presence of signs of systemic changes as a result of applying a hemostatic tourniquet, the presence of potentiating effects of reperfusion syndrome with a combined injury of the abdominal cavity against the ground of hypovolemic shock.


Keywords


trauma; abdominal cavity; bleeding; experiment; reperfusion

Full Text:

PDF

References


World Health Organization. Global burden of disease, 2004 update Geneva: WHO Press; 2008.

World Health Organization. Global status report on road safety 2013: supporting a decade of action Geneva: WHO Press; 2013.

Pfeifer, R., Teuben, M., Andruszkow, H., Barkatali, B.M., & Pape, H.-C. (2016). Mortality Patterns in Patients with Multiple Trauma: A Systematic Review of Autopsy Studies. Plos One. – 2016. – Vol. 11 (2). doi: 10.1371/journal.pone.0148844

Pfeifer, R., Tarkin, I.S., Rocos, B., & Pape, H.C. (2009). Patterns of mortality and causes of death in polytrauma patients-has anything changed? Injury, 40 (9), 907–911. doi: 10.1016/j.injury.2009.05.006

National Consortium for the Study of Terrorism and Responses to Terrorism (START). (2015). Global Terrorism Database. University of Maryland.

Regens, J.L., Schultheiss, A., & Mould, N. (2015). Regional Variation in Causes of Injuries among Terrorism Victims for Mass Casualty Events. Front Public Health., 3, 198.

Champion, H.R., Holcomb, J.B., & Young, L.A. (2009). Injuries from explosions. J Trauma, 66 (5), 1468-1477.

Zouris, J.M., Walker, G.J., Dye, J., & Galarneau, M. (2006). Wounding patterns for U.S. marines and sailors during operation Iraqi freedom, major combat phase. Mil Med, 171 (3), 246-252.

Cernak, I., & Noble-Haeusslein, L.J. (2010). Traumatic brain injury: an overview of pathobiology with emphasis on military populations. J Cereb Blood Flow Metab, 30, 255-266. DOI: 10.1038/jcbfm.2009.203.

Cole, L.A., Wagner, K., Scott, S., Connell, N.D., Cooper, A., Kennedy, C.A.,…, & Lamba, S. (2014). Terror medicine as part of the medical school curriculum. Front Public Health, 2, 138. DOI: 10.3389/fpubh.2014.00138.

Heldenberg, E., Givon, A., Simon, D., Bass, A., Almogy, G., & Peleg, K. (2014). Terror attacks increase the risk of vascular injuries. Front Public Health, 2, 47. DOI: 10.3389/fpubh.2014.00047.

Gholipour, C., Rad, B.S., Vahdati, S.S., Ghaffarzad, A., & Masoud, A. (2016). Evaluation of preventable trauma death in emergency department of Imam Reza hospital. World J Emerg Med. 7 (2), 135-137.

Eyi, Y.E., Toygar, M., Karbeyaz, K., Kaldırım, Ü., Tuncer, S.K., & Durusu, M. (2015). Evaluation of autopsy reports in terms of preventability of trauma deaths. Ulus Travma Acil Cerrahi Derg, 21, 127-133.

Eastridge, B.J., Mabry, R.L., Seguin, P., Cantrell, J., Tops, T., Uribe, P., …, & Blackbourne, L.H. (2012). Death on the battlefield (2001-2011): implications for the future of combat casualty care. J Trauma Acute Care Surg., 73 (6 Suppl 5), S431-437.

Butler, F.K.Jr. (2017). Tactical combat casualty care: transitioning battlefield lessons learned to other austere environments. Tactical Combat Casualty Care: Beginnings. Fuhm Wilderness & Environmental Medicine, 28, S12-S17.

Eastridge B.J., Hardin M., Cantrell, J., Oetjen-Gerdes, L., Zubko, T., Mallak, C., & Blackbourne, L.H. (2011). Died of Wounds on the Battlefield: Causation and Implications for Improving Combat Casualty Care (J Trauma.;71: S4 –S8)

Bochicchio, G. (2007). Treatment of bleeding in the urban battlefield. Surgery, 142, S78-S83.

Kotwal, R.S., Montgomery, H.R., Kotwal, B.M., Champion, H.R., Butler, F.K.Jr, Mabry, R.L., …, & Holcomb, J.B. (2011). Eliminating Preventable Death on the Battlefield. Arch Surg., 146 (12), 1350-1358.

Lee, С., Porter, K.M., & Hodgetts, T.J. (2007). Tourniquet use in the civilian prehospital setting. Emerg Med J., 24 (8), 584-587.

Van der Spuy, L. (2012). Complications of the arterial tourniquet. South Afr J Anaesth Analg, 18 (1), 14-18.

Wright, G., Mcdonald, V.S., & Smith, V.G. (2015). Whould civilian pre-hospital emergency care provision include tourniquets for the management of uncontrolled traumatic haemorrhage? Australasian Journal of Paramedicine, 12 (4), 1-5.

Murphy, E., & Steenbergen, C. (2008). Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol. Rev., 88 (2), 581-609.

Francischetti, I., Moreno, J.B., Scholz, M., & Yoshida, W.B. (2010). Leukocytes and the inflammatory response in ischemiareperfusion injury. Rev. Bras. Cir. Cardiovasc, 25 (4), 575-584.

Nagornaya, N.V., & CHetverik, N.A. (2010). Oksidativnyj stress: vliyanie na organizm cheloveka, metody ocenki [Oxidative stress: effect on the human body, assessment methods]. Zdorovia dytyny – Health of the child, 2, 140-145 [in Ukrainian].

Ste-fanov, O.V. (Ed.) (2001). Doklіnіchnі doslіdzhennia lіkarskih zasobіv : metod. rek. [Preclinical drug research: Guidelines]. Kyiv: Avіcenna, p. 528 [in Ukrainian].

Chevari, S., Chaba, I., & Sekeǐ, I. (1985). Rol superoksiddismutazy v okislitelnykh protsessakh kletki i metod opredeleniia ee v biologicheskikh materialakh [Role of superoxide dismutase in cellular oxidative processes and method of its determination in biological materials]. Laboratornoe delo – Laboratory matters, 11, 678-681 [in Russian].

Korolyuk, M.A., Ivanova, L.I., Mayorova, I.G., & Tokarev, V.Ye. (1988). Metod opredeleniya aktivnosti katalazy [Method for determination of catalase activity]. Laboratornoe delo – Laboratory matters, 1, 16-19 [in Russian].

Volotovska, N.V., Nhokwara, T.C., & Zhulkevych, I.V. (2019). Zminy aktyvnosti hlutationovoi systemy vnutrishnikh orhaniv u pershi hodyny eksperymentalnoho ishemichno-reperfuzinoho syndromu kintsivky, poiednanoho z krovovtratoiu ta mekhanichnoiu travmoiu [Changes in the glutathione system's activity of internal organs in the first hours of experimental limb ischemia-reperfusion syndrome, combined with blood loss and mechanical injury]. Zdobutky klinichnoi i eksperymentalnoi medytsyny – Achievements of Clinical and Experimental Medicine, 1, 23-27. DOI 10.11603/1811-2471.2019.v0.i1.10043

Nadraha, B.O., Strus, Kh.I., Yashchenko, A.M., Zhulkevych, I.V., & Lutsyk, O.D. (2019). Osoblyvosti hlikomu strukturnykh komponentiv miokarda shchura za umov eksperymentalnoi ishemii miokarda [Features of glycom structural components of rat myocardium under experimental myocardial ischemia]. Svit medytsyny ta biolohii – World of Medicine and Biology, 3(69), 197-203 [in Ukrainian].

Maksymyuk, V.V., Sheremet, M.I., Tarabanchuk, V.V., Shidlovskyi, O.V., Brodovsky, S.P., Zhulkevych, I.V., ..., & Holiar, O.I. (2019). Pathogenetic Features of Lipid and Protein Peroxide Oxidation Due to Experimental Acute Necrotizing Pancreatitis. Archives of the Balkan Medical Union, 54 (2), 235-244. DOI: https://doi.org/10.31688/ABMU.2019.54.2.03].

Nikolayev, V.H., Klishch, I.M., Zhulkevych, I.V., Oleshchuk, O.M., & Nikolayeva. V.V. Zastosuvannia preparatu Enteroshel dlia profilaktyky oksydatyvnoho stresu pry hostrii krovovtrati [Application of Enterosgel preparation for the prevention of oxidative stress in acute blood loss]. Visnyk naukovykh doslidzhen – Bulletin of scientific researches, 1, 72-74 [in Ukrainian].


Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM




Journal of Education, Health and Sport formerly Journal of Health Sciences

Declaration on the original version.

Editors indicates that the main version of the magazine is to issue a "electronic".

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

Archives 2011 - 2014

PBN 2011 - 2014

https://pbn.nauka.gov.pl/sedno-webapp/search?search&searchCategory=WORK&filter.inJournal=36616

POL-index 2011 - 2014

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-32a319c5-a850-4f44-ba70-1418a6087655

BASE 2011 - 2014

https://www.base-search.net/Search/Results?lookfor=Journal+of+Health+Sciences+%28Radom%29&type=all&oaboost=1&ling=1&name=&thes=&refid=dcrespl&newsearch=1

http://elibrary.ru/contents.asp?titleid=37467

http://journal.rsw.edu.pl/index.php/JHS/issue/archive

Indexed in Bases, Bazy indeksacyjne: ERIH Plus, Worldcat, PBN/POL-Index, ICI Journals Master List, Directory of Open Access Journals (DOAJ), ZBD, Ulrich's periodicals, Google Scholar, Polska Bibliografia Lekarska, EuroPub database, NLM Catalog Result - NCBI, BASE, Russian Sciences Index, Arianta.

https://zdb-katalog.de/title.xhtml?idn=1080187162

https://europub.co.uk/journals/22625

US NLM = 101679844

101679844 - NLM Catalog Result - NCBI

https://www.ncbi.nlm.nih.gov/nlmcatalog/101679844

Find a library that holds this journal: http://worldcat.org/issn/23918306

 

PBN Poland

https://pbn.nauka.gov.pl/sedno-webapp/journals/49068

POL-index

https://pbn.nauka.gov.pl/polindex-webapp/browse/journal/journal-c39c8169-88d2-45db-9e7f-d948ce9981c4

BASE

https://www.base-search.net/Search/Results?join=AND&bool0[]=AND&lookfor0[]=2391-8306&type0[]=all&page=11&l=pl&oaboost=1&refid=dcpagepl

Redaction, Publisher and Editorial Office

Publisher and Editorial Office
Department of Physical Culture,
Faculty of Earth Sciences and Spatial Management,
Nicolaus Copernicus University in Toruń, Poland
Address: Str. Lwowska 1, 87-100 Toruń, Poland

  Open Access ISSN 2391-8306 formerly ISSN: 1429-9623 / 2300-665X

The journal has been approved for inclusion in ERIH PLUS.

The ERIH PLUS listing of the journal is available at https://dbh.nsd.uib.no/publiseringskanaler/erihplus/periodical/info?id=485984

Indexed in Index Copernicus Journals Master List.

http://journals.indexcopernicus.com/Journal+of+Education+Health+and+Sport,p24782242,3.html

ICV 2018 = 95.95 ICV 2017 = 91.30 ICV 2016 = 84.69 ICV 2015 = 93.34 ICV 2014 = 89.51 Standardized Value: 8.27 ICV 2013: 7.32 ICV 2012: 6.41 ICV 20115.48

 

Indexed in Polish Scholarly Bibliography (PBN) (PBN Polska Bibliografia Naukowa) (https://pbn.nauka.gov.pl/journals/36616)

is a portal of the Polish Ministry of Science and Higher Education, collecting information on publications of Polish scientists and on Polish and foreign scholarly journals. Polish Scholarly Bibliograhpy is a part of POL-on - System of Information on Higher Education. It is operated by the Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw.

Indexed in Russian Sciences Index Российский индекс научного цитирования (РИНЦ) http://elibrary.ru/contents.asp?titleid=37467

Indexed in Arianta Polish scientific and professional electronic journals Aneta Drabek i Arkadiusz Pulikowski

(http://www1.bg.us.edu.pl/bazy/czasopisma/czasop_full.asp?id=3595)

Partnerzy platformy czasopism