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Journal of Education, Health and Sport

The level of endogenic intoxication in the dynamics of development of experimental contact dermatitis and experimental pneumonia and their correction by thiotriazoline
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  • The level of endogenic intoxication in the dynamics of development of experimental contact dermatitis and experimental pneumonia and their correction by thiotriazoline
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The level of endogenic intoxication in the dynamics of development of experimental contact dermatitis and experimental pneumonia and their correction by thiotriazoline

Authors

  • M. M. Regeda-Furdychko Lviv Medical Institute

DOI:

https://doi.org/10.12775/JEHS.2019.09.11.026

Keywords

contact dermatitis, pneumonia, endogenous intoxication, thiotriazoline

Abstract

Тhe aim of our work was to find out the peculiarities of changes ofendogenous intoxication indices in guinea pig blood during theformation of combined pathology - experimental contact dermatitis and experimental pneumonia and correction of their disorders with thiotriazoline.The paper found a gradual increase in the molecules of mediummass and erythrocyte index of intoxication in guinea pig serum with experimental contact dermatitis and experimental pneumonia with the highest degree of expression on the 18thday of the experiment, and this may be may indicate the development of endogenous intoxication of the animal body. At the same time, the use of the drug thiotriazoline caused the decrease of the studied indicators, which gives grounds to stateits positive effect on certain markers of endogenous intoxicationand the feasibility of further research.

References

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Kolishetska M.A Characteristic of individual indicators of endogenous intoxication in the experimental asthma dynamics and their correction by thiotriazolin. EUREKA :Health Sciences. 2016. Vol. 6, № 6. P. 52–56.

Shlyapnykov V.N., Solodova T.L. et al. Eksperimentalnye modeli ostrykh pnevmoniy, vyzvanykh uslovno-patolohicheskimi bakteriyami I ikh assotsiatsiey: metod. ukazaniya sost. Saratov, 1998. 30 p.

Volchegorskiy, I. A., Diatlov, D. A., Lvovskaya, E. I. et. al. (1997). Middle molecules" as probable regulators of erythrone system in skiers. Lab. Diagnostic, 1, 11–16.

Shmoilov, D. K., Karimov, I. Z., Odynets, T. N. (2012). Pathogenic role of endogenous intoxication. Lab. Diagnostic, 2, 65–69.

Kostner, L., Anzengruber, F., Guillod, C., Recher, M., Schmid-Grendelmeier, P., & Navarini, A. A. (2017). Allergic contact dermatitis. Immunology and Allergy Clinics, 37 (1), 141-152.

Diagnosis and treatment of community-acquired pneumonia in adults: 2016 clinical practice guidelines by the Chinese Thoracic Society, Chinese Medical Association B. Cao, Y. Huang, D.Y. She, Q.J. Cheng, H. Fan, X.L. Tian, et al. Clin Respir J, 12 (2018), pp. 1320-1360

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Published

2019-11-29

How to Cite

1.
REGEDA-FURDYCHKO, M. M. The level of endogenic intoxication in the dynamics of development of experimental contact dermatitis and experimental pneumonia and their correction by thiotriazoline. Journal of Education, Health and Sport. Online. 29 November 2019. Vol. 9, no. 11, pp. 287-292. [Accessed 7 July 2025]. DOI 10.12775/JEHS.2019.09.11.026.
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Issue

Vol. 9 No. 11 (2019)

Section

Research Articles

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The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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