Antibacterial effect of nisin in vitro
DOI:
https://doi.org/10.12775/JEHS.2020.10.12.032Keywords
nisin, carbopol, bacteriocins, antibioticsAbstract
Results of experimental studies of antimicrobial action of gel compositions containing active substance nisin are presented in the article. It is shown that increasing concentration of nisin at constant concentrations of the other components in the mixture inhibits growth of Staphylococcus aureus and Pseudomonas aeruginosa. The optimal concentration of nisin at which the process of pathogens growth inhibition is the most effective was determined in the experiment.
References
Dowset, C. The management of surgical wounds in a community setting / C. Dowset // Br. J. Communitu Nurs. – 2002. – # 7. – P. 33–38.
. R.S. Sufriyarov, Z.G. Gabidullin, R.R. Sufriyarov, A.A. Akhtarieva, V.G. Tujgunova. Lechenie assocziirovanny`kh gnojny`kh ran czitrobakterno-stafilokokkovoj prirody` // Vestnik YuUrGU, #26, 2011, S.108–111. (in Russian).
Kai Li, Lici А. Schuгig-Bгiccio, Xinxin Feng, Ashutosh Upadhyay, Venugopal Рujаri, et. аl.. Multitarget Drug Discovery for Tuberculosis аnd Other lnfectious Diseases. // J. Med. Chem. – 2014.– #57. – P. 3126–3139.
Ville Ojala, Jarkko Laitalainen, Matti Jalasvuori. Fight evolution with evolution: plasmid-dependend phages with a wide host гаnge ргеvеnt the spread of antibiotic resistance. // Evol Appl.– 2013.– #6.– P. 925-932.
A.V. Frolova, A.N. Kosinecz, V.K. Okulich. Ranevaya infekcziya. Sostoyanie problemy`. // Vestnik VGMU. Mikrobiologiya.– 2014.– T.13, #2. S.62–69. (in Russian).
Golub A.V., Privol`nev V.V. Mestnaya antibakterial`naya terapiya khirurgicheskikh infekczij kozhi i myagkikh tkanej v ambulatorny`kh usloviyakh: slagaemy`e uspekha // Rany` i ranevy`e infekczii. – 2014. – # 1. – S. 33-39. (in Russian).
Privol`nev V.V., Paskhalova Yu.S., Rodin A.V. Mestnoe lechenie ran i ranevoj infekczii po rezul`tatam anonimnogo anketirovaniya khirurgov Rossii // Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya. – 2016. – T. 18, # 2. – S. 152-158. (in Russian).
Раul D. Cotter, R. Раul Ross, Colin Hill. Bacteriocins – а viable alternative to antibiotics?. // Nat Rev Мiсrо. – 2012.– #11.– P.95–105.
Sumаnрrееt Каur, Sukhraj Каur. Bacteriocins as Potential Аntiсаnсеr Agents. // Front. Pharmacol.– 2015. – #6.– Р.1–11.
Luс De Vuyst, Frederic Lеrоу. (). Bacteriocins from Lactic Acid Bacteria: Production, Purification, and Food Applications. // J Mol Microblol Biotechnol.– 2007.– #13.– P.194–199.
Minah C.J., Моrеrо R.D. Inhibition of еntегосin CRL35 antibiotic activity bу mоnо- and divalent ions // Lett. Appl. Microbiol. – 2003. – Vol. 37, # 5. – Р. 374-379.
De Vuyst L., Lеrоу F Bacteriocins from Lactic Acid Bacteria: Production, Purification, and Food Applications // Mol. Microblol. Biotechnol. – 2007. – Vol. 13. – Р. 194–199.
Oscariz J.C., Pissabarro A.G. Classification and mode of action of membrane-active bacteriocins produced bу grampositive bacteria // Int. Microblol. – 2011. – #18. – Р. 13–19.
Bittencourt Е., Suzart S. Occurreonce of virulence-associated genes in clinical Enterococcus fae-calis strains isolated in Londrina, Brazil // J. Med. Microblol. – 2004. – Vol. 53. – Р. 1069–1073.
Surugau L.N. Peptide separation bу capillary electrophoresis with ultraviolet detection: some simple approaches to enhance detection sensitivity and resolution // The Malaysian Journal of Analytical Sciences. – 2011. – Vol. 15 (2). – Р. 273-287.
Volyans`ky`j Yu.L. Metody`chni rekomendaciyi po vy`vchennyu specy`fichnoyi akty`vnosti proty`mikrobny`x likars`ky`x zasobiv / Yu.L. Volyans`ky`j, I.S. Gry`shhenko, V.N. Shy`robokov ta in.– K.: 2004.– S.21–22. (in Ukrainian).
Downloads
Published
How to Cite
Issue
Section
License
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 470
Number of citations: 0
