The effectiveness of the application of nanomaterial polymer technologies in a comprehensive approach to surgical treatment of soft tissue wounds

Abstract

Treatment of purulent wounds remains one of the most important problems of surgery, both theoretically and practically. The aim was to study the effect of biodegradable polymer film "biodep-nano" and hydrated fullerene C60 on the healing of soft tissue wounds and prevention of their infection. We observed 124 patients with purulent-inflammatory soft tissue complications. Scientific group 53 (42.7%) patients who, in addition to complex treatment, performed the proposed therapy. The control group consisted of 71 (57.2%) patients who were treated according to conventional methods. The results showed that the temperature of the study area in the main group returned to normal on the 3rd day (2.8 ± 0.2 days), and in the group where traditionally used wipes on the 5-7th (5.9 ± 0, 4) the day where (p <0.05). Note that the average time of postoperative wound cleansing in patients of the control group was 14.1 ± 0.8 days, the appearance of granulation tissue - 15.6 ± 0.9 days, and the beginning of the marginal epithelialization - 18.4 ± 1.0 days The length of stay of patients in this group on an inpatient bed was 34.3 ± 2.8 days. Thus, from a surgical point of view, a new promising alternative is a combination of surgical treatment of wounds and the use of nano-containing biodegradable polymeric material, which not only destroys pathogenic wound flora, but also can prevent re-infection and purulent-inflammatory recurrence.