The use of peppermint oil in the treatment of irritable bowel syndrome
DOI:
https://doi.org/10.12775/JEHS.2020.10.06.003Keywords
irritable bowel syndrome, IBS, peppermint, peppermint oilAbstract
Irritable bowel syndrome (IBS) is a a chronic functional gastrointestinal disorder, that affects large intestine. The symptoms of IBS include: abdominal pain, discomfort, change in bowel habits and disordered defecation. The causes of irritable bowel syndrome have not yet been fully investigated and determined.
Peppermint (Mentha ×piperita) is a hybrid type of mint, a cross between watermint (Mentha aquatica) and spearmint (Mentha spicata). Peppermint oil is produced in the proces of steam distillation of fresh leaves of peppermint.
The aim of this study was to evaluate the use of peppermint oil in the treatment of irritable bowel syndrome. Our study material consisted of publications, which were found in PubMed, ResearchGate and Google Scholar databases. The first step was to find proper publications from the last 30 years. The second step was to carry out an overview of the found publications.
Based on the results of mentioned studies it can be concluded that peppermin oil is effective in the treatment of irritable bowel syndrome due to providing global symptom improvement and significant reduction of abdominal pain, and its short-term use is safe. However, further research is needed to estabilish the role of peppermint oil in the treatment of irritable bowel syndrome and to determine the optimal duration of treatment, dosage of peppermint oil, and its possible side effects related to long-term usage.
References
Alammar N, Wang L, Saberi B, et al. The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. BMC Complement Altern Med. 2019;19(1):21.
Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA. 2015;313(9):949‐958.
Kligler B, Chaudhary S. Peppermint oil. Am Fam Physician. 2007;75(7):1027‐1030.
Grigoleit HG, Grigoleit P. Gastrointestinal clinical pharmacology of peppermint oil. Phytomedicine. 2005;12(8):607‐611.
Cash BD, Epstein MS, Shah SM. A novel delivery system of peppermint oil is an effective therapy for irritable bowel syndrome symptoms. Dig Dis Sci.2016;61(2):560–71.
Merat S, Khalili S, Mostajabi P, Ghorbani A, Ansari R, Malekzadeh R. The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome. Dig Dis Sci. 2010;55(5):1385–90.
Liu JH, Chen GH, Yeh HZ, Huang CK, Poon SK. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol. 1997;32(6):765–8.
Cappello G, Spezzaferro M, Grossi L, Manzoli L, Marzio L. Peppermint oil (Mintoil((R))) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial. Dig Liver Dis. 2007;39(6):530–6.
Capanni M, Surrenti E, Biagini MR, Milani S, Surrenh C, Galli A. Efficacy of peppermint oil in the treatment of irritable bowel syndrome: a randomized, controlled trial. Gazz med ital arch sci med [Internet]. 2005; 164(2):119–26.
Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr. 2001;138(1):125‐128.
Lech Y, Olesen KM, Hey H, Rask-Pedersen E, Vilien M, Ostergaard O. Treatment of irritable bowel syndrome with peppermint oil. A double-blind investigation with a placebo. Ugeskr Laeger. 1988;150(40):2388–9.
Hills JM, Aaronson PI. The mechanism of action of peppermint oil on gastrointestinal smooth muscle. Gastroenterology 1991;101:55–65.
Pietrzak A, Skrzydło-Radomańska B, Mulak A, et al. Guidelines on the management of irritable bowel syndrome: In memory of Professor Witold Bartnik. Prz Gastroenterol. 2018;13(4):259‐288.
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