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Journal of Education, Health and Sport

The importance of vitamin D3 supplementation in orthopedics - literature review
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The importance of vitamin D3 supplementation in orthopedics - literature review

Authors

  • Dominik Machaj Faculty of Medicine, Medical University of Lublin, Chodźki Street 19, 20-093 Lublin
  • Katarzyna Cyboran Medical Faculty, Institute of Medical Sciences, Collegium Medicum, Oleska Street 48, 45-052 Opole
  • Alicja Płaczek Medical Faculty, University of Rzeszow, Pigonia Street 6, 35-310 Rzeszow
  • Marlena Baran Medical Faculty, University of Rzeszow, Pigonia Street 6, 35-310 Rzeszow
  • Michał Wojnowski Medical Faculty, University of Rzeszow, Pigonia Street 6, 35-310 Rzeszow

DOI:

https://doi.org/10.12775/JEHS.2020.10.05.011

Keywords

vitamin D3, orthopedics, fractures, falls

Abstract

Falls have been recognized by the WHO as one of the most significant problems in aging societies. In the elderly after 65 years of age, they cause 90% of the fractures of the proximal femoral bone (bkk) and 100% of the forearm fractures [5].They usually occur when walking (most often), getting up and sitting down. The consequences of falls, as well as themselves, can be prevented by supplementing vitamin D3 [6] [8] regulating the body's calcium-phosphate homeostasis. It improves neuromuscular function, including the mechanism reduces the frequency of falls. It also affects response time and balance. The concentration of vitamin D3 in the body is variable. Depends on endogenous biosynthesis and food supply. It also shows seasonal fluctuations. Its deficiencies lead to not only orthopedic and dental complications. It has been proven that there is a decreased level of 25 (OH) D3 in serum and such diseases as diabetes, hypertension, depression,neuro-degenerative diseases including Alzheimer's disease and increased likelihood of cancer, especially breast, prostate, and colon cancers [15].

References

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Holick, M. F. (2017). The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention. Reviews in Endocrine and Metabolic Disorders, 18(2), 153-165.

Jorgensen, H. L., Scholler, J., Sand, J. C., Bjuring, M., Hassager, C., & Christiansen, C. (1996). Relation of common allelic variation at vitamin D receptor locus to bone mineral density and postmenopausal bone loss: cross sectional and longitudinal population study. Bmj, 313(7057), 586-590.

Zimber, A., Chedeville, A., Abita, J. P., Barbu, V., & Gespach, C. (2000). Functional interactions between bile acids, all-trans retinoic acid, and 1, 25-dihydroxy-vitamin D3 on monocytic differentiation and myeloblastin gene down-regulation in HL60 and THP-1 human leukemia cells. Cancer research, 60(3), 672-678.

Czerwiński, E., & Kumorek, A. (2012). Falls, vitamin D and fractures. Postępy Nauk Medycznych.

Bischoff-Ferrari, H. A., Dawson-Hughes, B., Staehelin, H. B., Orav, J. E., Stuck, A. E., Theiler, R., ... & Henschkowski, J. (2009). Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. Bmj, 339, b3692.

Marcinowska-Suchowierska, E., Walicka, M., Tałałaj, M., Horst-Sikorska, W., Ignaszak-Szczepaniak, M., & Sewerynek, E. (2010). Vitamin D supplementation in adults-guidelines. Endokrynologia Polska, 61(6), 723-729.

Papadimitropoulos, E. (2002). Osteoporosis Methodology Group and The Osteoporosis Research Advisory Group. Meta-analyses of therapies for postmenopausal osteoporosis. VIII: Meta-analysis of the efficacy of vitamin D treatment in preventing osteoporosis in postmenopausal women. Endocr Rev., 23, 560-569.

Dhesi, J. K., Jackson, S. H., Bearne, L. M., Moniz, C., Hurley, M. V., Swift, C. G., & Allain, T. J. (2004). Vitamin D supplementation improves neuromuscular function in older people who fall. Age and ageing, 33(6), 589-595.

Szymański, F. M., Bomba-Opoń, D. A., Łęgosz, P., Głogowska-Szeląg, J., Baran, W., Szepietowski, J. C., ... & Kozłowska-Wojciechowska, M. (2015). Miejsce witaminy D w codziennej praktyce klinicznej—interdyscyplinarne stanowisko ekspertów. In Forum Medycyny Rodzinnej (Vol. 9, No. 6, pp. 423-434).

Czerwiński, E., Borowy, P., Kumorek, A. W. D., & Witamina, D. (2012). a układ mięśniowo-szkieletowy. Stand Med, 5, 651-652.

Trivedi, D. P., Doll, R., & Khaw, K. T. (2003). Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. Bmj, 326(7387), 469.

Avenell, A., Gillespie, W. J., Gillespie, L. D., & O'Connell, D. (2005). Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post‐menopausal osteoporosis. Cochrane Database of Systematic Reviews, (3).

Płudowski, P., Karczmarewicz, E., Bayer, M., Carter, G., Chlebna-Sokół, D., Czech-Kowalska, J., ... & Głuszko, P. (2013). Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe—recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency. Endokrynologia Polska, 64(4), 319-327.

Naeem, Z. (2010). Vitamin d deficiency-an ignored epidemic. International journal of health sciences, 4(1), V.

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Published

2020-05-14

How to Cite

1.
MACHAJ, Dominik, CYBORAN, Katarzyna, PŁACZEK, Alicja, BARAN, Marlena and WOJNOWSKI, Michał. The importance of vitamin D3 supplementation in orthopedics - literature review. Journal of Education, Health and Sport. Online. 14 May 2020. Vol. 10, no. 5, pp. 118-122. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2020.10.05.011.
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Vol. 10 No. 5 (2020)

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