Acute kidney injury related to wild mushrooms intoxication

Authors

  • Małgorzata Marchelek-Myśliwiec Clinic of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin
  • Aleksandra Wilk Department of Histology and Embryology, Pomeranian Medical University, Szczecin
  • Agnieszka Turoń-Skrzypińska Department of Medical Rehabilitation and Clinical Rehabilitation, Pomeranian Medical University in Szczecin
  • Monika Nowosiad-Magda Department of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University, Szczecin
  • Grazyna Dutkiewicz Clinic of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin
  • Barbara Dołęgowska Department of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University, Szczecin, Poland
  • Joanna Stępniewska Clinic of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin, Poland
  • Kazimierz Ciechanowski Clinic of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin
  • Barbara Wiszniewska Department of Histology and Embryology, Pomeranian Medical University, Szczecin, Poland

DOI:

https://doi.org/10.12775/JEHS.2020.10.01.005

Keywords

Wild mushroom intoxication, Nephrotoxicity, Kidney insufficiency, Orellanine nephrotoxicity, Amatoxin nephrotoxicity, Paxillus syndrome

Abstract

The problem of mushroom intoxication has been brought up more often in both scientific journals and media, particularly in autumn – the period when mushroom hunting is most intense. Mushroom intoxication is mainly perceived as being associated with acute hepatic insufficiency. However, apart from strong hepatotoxic effects, some mushroom species are characterized by effects that lead to renal damage, sometimes irreversible in character. This article relates to the toxic mushroom species considered to be nephrotoxic and discusses different mechanisms and symptoms of kidney injury as well as methods of treatment

References

Marciniak B, Ferenc T, Kusowska J, Ciećwierz J, Kowalczyk E. Poisoning with selected mushrooms with neurotropic and hallucinogenic effect. Med Pr. 2010;5:583-595.

Grzymała S. Śmiertelne zatrucia rzekomo jadalnym gatunkiem grzyba III. Wyodrębnienie trującej substancji - orellaniny. Rocz Państw Zakł Hig. 1961;12:491-498.

Kilner RG, D'Souza RJ, Oliveira DB. Acute renal failure from intoxication by Cortinarius orellanus: recovery using anti-oxidant therapy and steroids. Nephrol Dial Transplant. 1999;14:2779-2780.

Prast H, Werner ER, Pfaller W, Moser M. Toxic properties of the mushroom Cortinarius orellanus. I. Arch toxicol. 1988;62:81-88.

Horn S, Horina JH, Krejs GJ, Holzer H, Ratschek. M. End-stage renal failure from mushroom poisoning with Cortinarius orellanus: report of four cases and review of the literature. Am J Kidney Dis. 1997;30:282-286.

Andary C, Rapior S, Delpech N, Huchard G. Laboratory confirmation of Cortinarius poisoning. Lancet. 1989;1(8631):213.

Short AI, Watling R, MacDonald MK, Robson JS. Poisoning by Cortinarius speciosissimus. Lancet. 1980;2:942-944.

Holmdahl J, Ahlmen J, Bergek S, Lundberg S, Persson S. Isolation and nephrotoxic studies of orellanine from the mushroom Cortinarius speciosissimus. Toxicon. 1987;25:195-199.

Raff E, Halloran PF, Kjellstrand CM. Renal failure after eating "magic" mushrooms. Can Med Assoc J. 1992;147:1339-1341.

Bouget J, Bousser J, Pats B. Acute renal failure following collective intoxication by Cortinarius orellanus. Intensive Care Med. 1990;16:506-510.

Leathem AM, Purssell RA, Chan VR. Renal failure caused by mushroom poisoning. J Toxicol Clin Toxic. 1997;1:67-75.

Warden CR, Benjamin DR. Acute renal failure associated with suspected Amanita smithiana mushroom ingestion: a case series. Acad Emerg Med. 1998;5:808-812.

Gerault A. Intoxication collective de type orellanien provoquee par Cortinarius splendens. R Hy. Bull Trimest Soc Mycol Fr. 1981;97:67-72.

Rapior S, Delpech N, Andary C,Huchard G. Intoxication by Cortinarius orrelanus: detection and assay of orellanine in biological fluids and renal biopsies. Mycopathologia. 1989;3:155-161.

Cantin D, Richard JM, Alary J. Chromatographic behaviour and determination of orellanine, a toxin from the mushroom Cortinarius orellanus. J Chromatogr. 1989;1:231-237.

Delpech N, Rapior S, Cozette AP. Outcome of acute renal failure caused by voluntary ingestion of Cortinarius orellanus. Presse med. 1990;3:122-124.

Diaz JH. Syndromic diagnosis and management of confirmed mushroom poisoning. Crit Care Med. 2005;33:427-436.

Nagaraya P, Thangarelu A, Nair H, Kumwenda M. Successful living related kidney transplantation for end-stage renal failure caused by orellanine syndrome. QMJ; 2015;5:413-415, https://dx.doi.org/10.1093/qjmed/hcs201.

Grebe SO, Langenbeck M, Schaper A, Berndt S, Aresmouk D, Herget-Rosenthal S. Antioxidant treatment and outcome of Cortinarius orellanus poisoning: a case series. Ren Fail. 2013;35:1436-1439, https://dx.doi.org/10.3109/0886022X.2013.826110 .

Shao D, Tang S, Healy RA, Imerman PM, Schrunk DE, Rumbeiha WK. A novel orellanine containing mushroom Cortinarius armillatus. Toxicon. 2016;114:65-74, https://dx.doi.org/10.1016/j.toxicon.2016.02.010.

Leray H, Canaud B, Andary C, Klouche K, Béraud JJ, Mion C. Intoxications with Amanita proxima - a new case of acute renal failure. Nephrologie. 1994;15:197-199.

Bedry R, Baudrimont I, Deffieux G, Creppy EE, Pomies JP, Ragnaud JM et al. Wild mushroom intoxication as a cause of rhabdomyolysis. N Engl J Med. 2001;345:798-802. https://dx.doi.org/10.1056/NEJMoa010581

Winkelmann M, Stangel W, Schedel I, Grabensee B. Severe hemolysis caused by antibodies against the mushroom Paxillus involutus and its therapy by plasma exchange. Klin Wochenschr. 1986;64:935-938.

Sein Anand J, Chwaluk P, Sut M. Acute poisoning with Tricholoma equestre. Przegl Lek. 2009;66:339-340.

Cho J, Han J. A case of mushroom poisoning with Russula Subnigricans: developement of rabdomiolysis, acute kidney injury, cardiogenic shock and death. J Korean Med Sci. 2016; 31(7):1164-1167, https://dx.doi.org/10.3346/jkms.2016.31.7.1164.

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Published

2020-01-17

How to Cite

1.
MARCHELEK-MYŚLIWIEC, Małgorzata, WILK, Aleksandra, TUROŃ-SKRZYPIŃSKA, Agnieszka, NOWOSIAD-MAGDA, Monika, DUTKIEWICZ, Grazyna, DOŁĘGOWSKA, Barbara, STĘPNIEWSKA, Joanna, CIECHANOWSKI, Kazimierz and WISZNIEWSKA, Barbara. Acute kidney injury related to wild mushrooms intoxication. Journal of Education, Health and Sport. Online. 17 January 2020. Vol. 10, no. 1, pp. 42-46. [Accessed 12 November 2024]. DOI 10.12775/JEHS.2020.10.01.005.

Issue

Vol. 10 No. 1 (2020)

Section

Review Articles

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