Cystic Fibrosis - Related Diabetes
DOI:
https://doi.org/10.12775/JEHS.2021.11.06.005Keywords
cystic fibrosis-related diabetes, beta cells, insulin therapyAbstract
Cystic fibrosis (CF) is life-shortening autosomal recessive disease, caused by mutations in the cystic fibrosis transmembrane conductance regulator protein. The most common of CF complications is cystic fibrosis-related diabetes (CFRD). The pathophysiology of CFRD is complex. The best test for screening and diagnosis of CFRD is the oral glucose tolerance test (OGTT). Insulin therapy is a treatment of choice in CFDR pharmacotherapy. An inseparable element of CFRD therapy is also physical activity and diet.
References
Cystic Fibrosis Foundation. 2019 Patient Registry: Annual Data Report. Avilable at: https://www.cff.org/Research/Researcher-Resources/Patient-Registry/2019-Patient-Registry-Annual-Data-Report.pdf
O'Sullivan BP, Freedman SD. Cystic fibrosis. Lancet 2009; 373:1891.
Mishra A, Greaves R, Smith K, et al. Diagnosis of cystic fibrosis by sweat testing: age-specific reference intervals. J Pediatr 2008; 153:758.
Kayani K, Mohammed R, Mohiaddin H. Cystic Fibrosis-Related Diabetes. Front Endocrinol (Lausanne). 2018;9:20.
Pozo L, Bello F, Mendez Y, Surani S. Cystic fibrosis-related diabetes: The unmet need. World J Diabetes 2020; 11(6): 213-217.
Granados A, Chan CL, Ode KL. Cystic fibrosis related diabetes: Pathophysiology, screening and diagnosis. J Cyst Fibros. 2019;18 Suppl 2:S3-S9.
Barrio R. Management of endocrine disease: Cystic fibrosis-related diabetes: novel pathogenic insights opening new therapeutic avenues. Eur J Endocrinol. 2015;172:R131-R141.
Sands D. Mukowiscydoza choroba wieloukładowa. Termedia. 2018: 229-239.
Moran A, Pillay K, Becker D, et al. ISPAD Clinical Practice Consensus Guidelines 2018: Management of cystic fibrosis-related diabetes in children and adolescents. Pediatr Diabetes 2018; 19 Suppl 27:64.
Ding S, Zhong C. Exercise and Cystic Fibrosis. Adv Exp Med Biol. 2020;1228:381-391. doi: 10.1007/978-981-15-1792-1_26. PMID: 32342472.
Radtke T, Nevitt SJ, Hebestreit H, Kriemler S. Physical exercise training for cystic fibrosis. Cochrane Database Syst Rev. 2017 Nov 1;11(11):CD002768. doi: 10.1002/14651858.CD002768.pub4. PMID: 29090734; PMCID: PMC6485991.
Ratajczak A, Zawada A, Moszak M. Dietary recommendations in cystic fibrosis related diabetes. Piel Zdr Publ. 2019;9(2):133–140.
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