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Journal of Education, Health and Sport

Immunuhistochemical features of the ovaries’ structure in case of fetuses with a gestational term of 21-28 weeks from mother, whose pregnancy was complicated by chronic infections of lower genital tracts
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  • Immunuhistochemical features of the ovaries’ structure in case of fetuses with a gestational term of 21-28 weeks from mother, whose pregnancy was complicated by chronic infections of lower genital tracts
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  3. Vol. 11 No. 5 (2021) /
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Immunuhistochemical features of the ovaries’ structure in case of fetuses with a gestational term of 21-28 weeks from mother, whose pregnancy was complicated by chronic infections of lower genital tracts

Authors

  • V. O. Poliyasnyi International Humanitarian University
  • L. S. Kupriianova International Humanitarian University

DOI:

https://doi.org/10.12775/JEHS.2021.11.05.026

Keywords

ovary, fetus, pregnancy, chronic infection, lower genital tract, collagen, enditheline-1, estrogen

Abstract

The following article presents results of the complex research on postulation of immunohistochemical features of the ovaries’ structure in case of fetuses with a gestational term of 21-28 weeks from mothers with HILGT comparing to ones in case of fetuses from mothers with a physiological pregnancy. The materials of the research are: 25 fetuses from mothers with HILGT as well as 25 fetuses from mothers with physiological pregnancy. All fetuses had died antenatally and inranatally, as a result of violation of uteroplacental and umbilical-uterine circulation. Research methods: macroscopic, organometric, histological, immunohistochemical, morphometric, statistical. The organometric method revealed a clear decrease of main indexes of the fetuses’ ovaries from mothers with a complicated pregnancy comparing to ones in case of organs of fetuses from healthy mothers. Morphometric method revealed a clear decrease of a relative volume of cortical substance as well as a clear increase of a relative volume of brain substance in the gonads of fetuses from the main group; as well as it showed a clear decrease of an index of follicular tissue’ relative volume, likewise a clear increase of an index of interstitial component relative volume.

The staining by picrofuxin by van Gieson method revealed a massive growth of the connective tissue in all strucutral components of organs of fetuses from mothers with HILGT relatively to gonads of fetuses from healthy mothers. Using of MCAT to main types of collagens allowed to reveal a violation of maturation of main types of collagens in the structure of connective tissue of fetal gonads in the main group. In the follicular component of the fetuses’ ovaries in the main group are appearing mature, cystic-artretic and growing forms of follicles. Immunohistochemical method revealed an increased number of an apoptotically altered eggs in the ovaries of fetuses from mothers with HILGT comparing to one in organs of fetuses from mothers with physiological pregnancy.  The peroxidase method revealed an increased endotheline-producing activity of the vascular component as arterial, like a venous type; likewise a clear decrease of the hormone-producing activity in the ovaries of fetuses from mothers with HILGT comparing to such indexes in fetal organs of fetuses from mothers with physiological pregnancy. The complex of changes in the ovaries of fetuses with a 21-28 weeks of gestational term, which was described, was formed under the influence of the chronic hypoxia, prolonged antigenic stimulation as well as hormonal violations in the mother-placenta-fetus system, which is a leading link of the infectious pathology’ pathogenesis. The aforementioned complex of the structural and functional changes in the ovaries of fetuses from mothers with HILGT in a gestational term of 21-28 weeks indicates violations in implementation and formation of the fetal gonads, as well as it could further lead to disorders of the germinal function in the female organism.

References

Baker D. A. Issues and management of herpes in pregnancy / D. A. Baker // Int. J. Fertil. Women Med. – 2012. – Vol. 47, № 3. – Р. 129-139.

Cao B. Placental microbiome and its role in preterm birth / В. Cao, M. J. Stout [et al.] // Neoreviews. – 2014. – № 1. – Р. 537-545.

Charlier C. Infection and pregnancy: a threat for mother and child / С. Charlier, М. Lecuit // Presse. Med. – 2014. – № 43. – Р. 662-4.

Chin T. L. Viral infections in pregnancy: advice for healthcare workers / T. L. Chin, А. Р. MacGowan [et al.] // Hosp. Infect. – 2014. – № 87. – Р. 11-24.

Conti N. Term histologic chorioamnionitis: a heterogeneous condition / N. Conti, М. Torricelli [et al.] // Eur. J. Obstet. Gynecol. Reprod. Biol. – 2015. – № 188. – Р. 34-8.

Akasha A. M. Immunohistochemistry in the ovary: Moving beyond the brown and blue / А. М. Akashа, А. Kato [et. al.] // Mol. Reprod. Dev. – 2017. – № 84 (3). – Р. 199.

Baker D. A. Issues and management of herpes in pregnancy / D. A. Baker // Int. J. Fertil. Women Med. – 2012. – Vol. 47, № 3. – Р. 129-139.

Baud D. Roles of bovine waddlia chondrophila and chlamydia trachomatis in human preterm birth / D. Baud, G. Goy, S. Vasilevsky [et al.] // New Microbes New Infect. – 2014. – № 29. – Р. 41-5.

Fatima U. Foetal autopsy-categories and causes of death / U. Fatima, R. Sherwani [et all] // Clin. Diagn. Res. – 2014. – № 8. – Р. 105-8.

Galbarczyk A. Polimorfizm genetyczny (CYP17, CYP19, CYP1A1 i CYP1B1) a stężenia hormonów płciowych u kobiet w wieku rozrodczym / A. Galbarczyk. – Uniwersytet Jagielloński. Collegium Medicum. Wydział Nauk o Zdrowiu. – Kraków, 2012. – 145 s.

Hulchiy M. Endometrial expression of estrogen receptors and the androgen receptor in women with polycystic ovary syndrome: a lifestyle intervention study / М. Hulchiy [et al.] // Clin. Endocrinol. Metab. – 2016. – № 101. – Р. 561-71.

Incebiyik A. Comparison of tissue prolidase enzyme activity and serum oxidative stress level between pregnant women with placental abruption and those with a healthy pregnacy / А. Incebiyik, М. Vural [et al.] // Arch. Gynecol. Obstet. – 2015. – № 291. – Р. 805-9.

Keskinkılıç B. Maternal mortality due to hypertensive disorders in pregnancy, childbirth, and the puerperium between 2012 and 2015 in Turkey: A nation-based study / В. Keskinkılıç, Y. Engin-Üstün [et al.] // Turk. Ger. Gynecol. Assoc. – 2017. – № 15. – Р. 20-25.

Katzman P. J. Chronic inflammatory lesions of the placenta / P. J. Katzman // Semin. Perinatol. – 2015. – № 39. – Р. 20-6.

Krawczyk М. А. Znaczenie ekspresji wybranych markerów hipoksji i indeksu proliferacyjnego Ki-67 u dzieci z mięsakami tkanek miękkich w ocenie aktywności choroby i prognozowaniu jej przebiegu / M. A. Krawczyk, A. Małgorzata. – Gdański Uniwersytet Medyczny. – Gdańsk: Gdański Uniwersytet Medyczny, 2016. – 160 s.

Kwit K. Pregnancy outcome and clinical status of gilts following experimental infection by H1N2, H3N2 and H1N1pdm09 influenza A viruses during the last month of gestation / К. Kwit, М. Pomorska-Mól, І. Markowska-Daniel // Arch. Virol. – 2015. – № 160. – Р. 2415-25.

Lazzarotto T. Diagnosis and prognosis of congenital CMV infection: a case report and review of the literature / Т. Lazzarotto, L. Gabrielli [et al.] // Scand. J. Clin. Lab. Invest. – 2014. – № 244. – Р. 34-40.

Alexandraki K. I. Endocrinopathies and other disorders inducing a polycystic ovary syndrome phenotype / K. I. Alexandraki, G. A. Kaltsas // Front. Horm. Res. – 2013. – № 40. – Р. 142-57.

Atukorale P. U. Vascular targeting of nanoparticles for molecular imaging of diseased endothelium / P. U. Atukorale, G. Covarrubias [et al.] // Adv. Drug. Deliv. Rev. – 2017. – № 113. – Р. 141-156.

Costache M. A comparison between clinical diagnosis of death and autopsy diagnosis. A retrospective study of 131 newborns, stillborns and aborted fetuses / М. Costache, М. Cirstoiu, А. [et al.] // Maedica (Buchar). – 2014. – № 9 (2). – Р. 183-8.

Di Renzo G. C. Progesterone in normal and pathological pregnancy / G. C. Di Renzo, I. Giardina [et al.] // Horm. Mol. Biol. Clin. Investig. – 2016. – № 1. – Р. 35-48.

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Published

2021-05-28

How to Cite

1.
POLIYASNYI, V. O. and KUPRIIANOVA, L. S. Immunuhistochemical features of the ovaries’ structure in case of fetuses with a gestational term of 21-28 weeks from mother, whose pregnancy was complicated by chronic infections of lower genital tracts. Journal of Education, Health and Sport. Online. 28 May 2021. Vol. 11, no. 5, pp. 246-261. [Accessed 27 September 2023]. DOI 10.12775/JEHS.2021.11.05.026.
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Vol. 11 No. 5 (2021)

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Research Articles

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