Non-invasive diagnostic methods of the liver fibrosis in patients with overweigh and obesity
DOI:
https://doi.org/10.12775/JEHS.2021.11.03.023Keywords
posthepatiс fibrosis, overweight, elastography, FibroTest, FIB-4 indexAbstract
One of the biggest problems of modern medicine is the difficulty in early diagnostic and effective treatment of HCV infection due to its wide distribution, latent form and terrible consequences as a formation of liver cirrhosis (CP) and hepatocellular carcinoma (HCC). It is important to mention, that the rate of progression of liver fibrosis. It is an important medical and social problem that the number of patients with NAFLD, overweight and obesity is constantly increases [9]. Due to the high prevalence of NAFLD and CHC, these two pathologies will progress and contribute to the progression of fibrosis, and depending on the genome of the virus and metabolic syndrome. There is a high risk of developing CP and HCC even after achieving a stable virological response.
The main aim of our investigation was to assess the stages of fibrosis by using non-invasive methods for patients with overweight and obesity who being treated for HCV infection (with posthepatic fibrosis).
References
Ivashkin, V.T. Faktory riska razvitiya gepatotsellyulyarnoy kartsinomy / V.T. Ivashkin, M.A. Morozova, M.V. Mayevskaya i dr. // Ros. zhurn. gastroenterologii, gepatologii, koloproktologii. – 2009. – V.19 (1). – S.4 –15.
Hajarizadeh B., Grebely J., Dore G.J. Epidemiology and natural history of HCV infection. // Nat Rev Gastroenterol Hepatol. – 2013. – V. 10. – p.553–562.
Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence / K.Hanafiah, J. Groeger, A. D. Flaxman, S. T. Wiersma. // Mohd. Hepatology. – 2013. – V.57. – p.1333–1342.
Lavanchy D. Evolving epidemiology of hepatitis C virus // Clin. Microbiol. Infec. – 2011. – Vol. 17 (2). – P. 107–115
World Health Organization (WHO). Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C virus infection. Revised July, 2018
Manne V et al. Cirrhosis regression in patients with viral hepatitis B and C: a systematic review. J Clin Gastroenterol. –2014 – 48(9) – p.76-84.
Kim JH et al. Clinical application of transient elastography in patients with chronic viral hepatitis receiving antiviral treatment. Liver Int. –2015. –35(4) –p.1103-1115.
Gorchag D. M. , Kholodkova O. L. , Perepelyuk M. M. Patogenez fіbrozu pechіnki ta mozhlivostі yogo korektsії.-Journal of Education, Health and Sport. – 2016. – 6(10) –p. 586-600.
Williams, C.D. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study / C.D. Williams [et al.] // Gastroenterology. – 2011. – № 140. – P. 124–131.
Adinolfi, L.E. NAFLD and NASH in HCV Infection: Prevalence and Significance in Hepatic and Extrahepatic Manifestations / L.E. Adinolfi [et al.] // International Journal of Molecular Sciences. – 2016. – № 6 (17). – P. 803.
Trifan A. Non-invasive evaluation of liver Ÿ brosis in chronic hepatitis C / A. Trifan, C. Cojocariu, Sfarti [et al.] // Rev. Med. Chir. Soc. Med. Nat. Iasi. – 2012. – № 116 (1). – P. 135–138.
Hermeziu B. Evaluation of FibroTest-ActiTest in children with chronic hepatitis C virus infection. Gastroenterol Clin Bio / B. Hermeziu, D. Messous, M. Fabre, M. Munteanu // Med. Pr. – 2010. – № 34 (1). – P. 16–22
Diomidova V.N., Petrova O.V. Sravnitel’nyj analiz rezul’tatov ehlastografii sdvigovoj volnoj i tranzientnoj ehlastografii v diagnostike diffuznyh zabolevanij pecheni. Ul’trazvukovaya i funkcional’naya diagnostika. – 2013. –No. 5. – р. 17–23.
Klyaritskaya I.L., Shelikhova E.O., Moshko Yu. A. Tranziyentnaya elastografiya v otsenke fibroza pecheni [Transient elastography in the assessment of liver fibrosis]. Krymskiy terapevticheskiy zhurnal. — 2015. — №3. — Р. 18-30.
Nightingale K. Acoustic radiation force impulse (ARFI) imaging: A review. Current Medical Imaging Reviews, 2011, Vol. 7 (4), рр. 328–339.
Stepanyan I.A., Kobinets Yu.V., Izranov V.A., Ovchinnikov O.I. Diffuse liver changes: assessment of ARFI-elastometry diagnostic efficacy. Diagnostic radiology and radiotherapy. 2018. —№1 —P. 30-35.
Ferraioli G., Tinelli C., Dal Bello B., Zicchetti M. Accuracy of real-time Shear Wave Elastography for assessing liver fibrosis in chronic hepatitis C: A pilot study // Hepatology.— 2012. — №56. — Р.2125-2133.
Noninvasive in vivo liver fibrosis evaluation using supersonic shear imaging: a clinical study on 113 hepatitis C virus patients / Bavu E., Gennisson J.L., Couade M. et al. // Ultrasound Med Biol.— 2011.— №37.— P.1361-1373.
Downloads
Published
How to Cite
Issue
Section
License
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 424
Number of citations: 0