Evaluation of antimicrobial activity of some compounds for purulent wounds treatment
DOI:
https://doi.org/10.12775/JEHS.2021.11.03.004Keywords
infections, silver, ectericide, nisinAbstract
Results of in vitro studies of antimicrobial compounds effect on clinical strains Staphylococcus aureus and Pseudomonas aeruginosa, causing purulent inflammation of open wounds are considered in the article. Activity of the compounds was determined according to the inhibition of the microorganisms growth by means of agar well diffusion method. Nisin and silver nitrate are shown to exhibit antimicrobial properties, while such classical antiseptics as ectericide and colloidal silver were inactive.
References
Gurusamy KS, Koti R, Toon CD, Wilson P, Davidson BR. Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds. Cochrane Database Syst Rev. 2013;(8):CD009726. Published 2013 Aug 20. doi:10.1002/14651858.CD009726.pub2.
Loginov V.I., Parshikov V.V., Kasimov R.R., Baburin A.B. Modern mechanical methods for intraoperative prevention of infections as pertaining to surgical intervention. Novosti Khirurgii, 2015, 23 (5): 559-565.
Dowset C. The management of surgical wounds in a community setting / C. Dowset // Br. J. Communitu Nurs. – 2002. – # 7. – P. 33–38.
Privolnev V.V., Paskhalova Yu.S., Rodin A.V., Mitish V.A. Topical treatment of wounds and wound infection based on the results of anonymous questioning of Russian surgeons. Rany i Ranevye Infektsii, 2016, 1: 19-24.
Privolnev V.V., Rodin A.V., Fedorov R.E., Khvostov D.L. Prospects for using topical antibiotic therapy for treatment of osteomyelitis. Vrach, 2016, 11: 12-16.
Chadaev, A.P. Gnojny`e zabolevaniya pal`czev i kisti / A.P. Chadaev, A.Cz. Butkevich, G.G. Savzyan. – M.: Gelikon, 1996. – 148 s. (in Russian)
Blatun, L.A. Flegmony` i absczessy`: sovremenny`e vozmozhnosti lecheniya / L. A. Blatun // Lechashhij vrach. – 2002. – # 1–2. – S. 30–40. (in Russian).
Golub A.V., Privol`nev V.V. Mestnaya antibakterial`naya terapiya khirurgicheskikh infekczij kozhi i myagkikh tkanej v ambulatorny`kh usloviyakh: slagaemy`e uspekha // Rany` i ranevy`e infekczii. – 2014. – # 1. – S. 33-39. (in Russian).
Frank D.N., Wysocki A., Specht-Glick D.D. Microbial diversity in chronic open wounds // Wound Repair Regen. – 2009. – 17. – Р. 163–172.
Norman G., Dumville J., Mohapatra D., Owens G., Crosbie E. Antibiotics and antiseptics for surgical wounds healing by secondary intention // Cochrane Database Syst. Rev. – 2016. – 3. – CD011712.
Klaine S.J., Alvarez P.J.J., Batley G.E., Fernandes T.F., Handy R.D., Lyon D.Y., Mahendra S., McLaughlin M.J., Lead J.R. Nanomaterials in the environment: Behavior, fate, bioavailability, and effects // Environmental Toxicology and Chemistry. – 2008. – Vol. 27. – № 9. – P. 1825 –1851.
Artemova A.Serebro isczelyayushhee i omolazhivayushhee / A. Artemova. – SPb.: Dilya Pablishing, 2001. – 137 c. (in Russian).
B.S. Atiyeh, M.Costagliola, S.N.Hayek, S.A. Dibo, Effect of silver on burn wound infection control and healing: review of the literature. // Burns.– 2007.– v. 33, №. 2, Р. 139–148.
Opal S.M., Medeiros A.A. Molecular mechanisms of antibiotic resistance in bacteria. In: Mandell G.L., Bennett J.E., Dolin R., editors. Principles and Practice of Infectious Diseases. 6th ed. Philadelphia: Churchill Livingstone; 2004. p. 253–270.
Abaeva L.F., Shumskij V.I., Petriczkaya E.N., Rogatkin D.A., Lyubchenko P.N. Nanochasticzy` i nanotekhnologii v mediczine segodnya i zavtra. // Al`manakh klinicheskoj medicziny`.–2010.– 22: S. 10–16. (in Russian).
Lewinski N., Colvin V., Drezek R. Cytotoxicity of Nanoparticles // Small J. 2008. V.4, No.1. Р.26-49.
N.S. Leonenko. Sravnitel`ny`j analiz toksichnosti i opasnosti khimicheskikh soedinenij razlichnoj razmernosti (obzor literatury`) // Suchasni` problemi toksikologi`yi, kharchovoyi ta khi`mi`chnoyi bezpeki.– 2016.– 2: S.48–67. (in Russian).
Kuleshova S.I. Opredelenie aktivnosti antibiotikov metodom diffuzii v agar // Vedomosti NCzE`SMP.– 2015.– # 3.– S. 13–17. (in Russian).
Volyans`kij Yu.L. Metodichni` rekomendaczi`yi po vivchennyu speczifi`chnoyi aktivnosti` protimi`krobnikh li`kars`kikh zasobi`v / Yu.L. Volyans`kij, I`.S. Grishhenko, V.N. Shirobokov ta i`n.– K.: 2004.– S.21–22. (in Russian).
Downloads
Published
How to Cite
Issue
Section
License
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 502
Number of citations: 0
