Immunohistochemical study of placental lactogen in the trophoblast in immaturity of the chorionic tree of the placenta on the background of iron deficiency anemia in pregnant women
DOI:
https://doi.org/10.12775/JEHS.2021.11.02.026Keywords
placental lactogen, iron deficiency anemia, trophoblast, chorionic tree immaturityAbstract
The study of placental lactogen by immunohistochemistry in histological sections of the placenta during physiological pregnancy and on the background of iron deficiency anemia in the aspect of chronic placental insufficiency. It is established that during gestation against the background of iron deficiency anemia decreases the production of placental lactogen by syncytiotrophoblast of the chorionic villi and correlates with the state of the blood of the pregnant woman. The optical density of immunohistochemical staining for placental lactogen of the free trophoblast reflects the degree of maturation of the chorionic tree of the placenta in iron deficiency anemia in pregnant women. Chronic placental insufficiency caused by immaturity of the chorionic villi can be compensated at the level of metabolism.
References
Garvasuk OV, Davydenko IS. Morfometrychni parametry peredchasnoho dozrivannia khorialnoho dereva platsenty pry zalizodefitsytnii anemii vahitnykh u hestatsiinomu aspekti [Morphometrical Parameters Of Preterm Maturing Of Placenta Chorial Tree In Pregnant Women With The Iron-Deficiency Anemia In Gestational Aspect]. Neonatolohiya, khirurhiya ta perynatalʹna medytsyna. 2015;5(4):90-95. [Ukrainian]
Davydenko IS, Tіulіenіeva OA, Hoshovsʹka AV. Histolohichni kryteriyi zrilosti khorialʹnoho dereva dlya diahnostyky peredchasnoho abo upovilʹnenoho dozrivannya platsenty lyudyny [Histological criteria of chorionic tree maturity for diagnosis of premature or delayed maturation of the human placenta]. Bukovynsʹkyy medychnyy visnyk. 2011;1(57):127-130. [Ukrainian]
Burton GJ, Fowden AL. The placenta: a multifaceted, transient organ. PhilosTrans R Soc Lond Ser BBiol Sci [Internet]. 2015[cited 2018 Dec 27]; 370(1663):20140066.
Benirschke K, Burton GJ, Baergen RN. Pathology of the human placenta. 2th ed. New York: Springer; 2011. 974 p.
Burton GJ, Fowden AL, Thornburg KL. Placental origins of chronic disease. Physiol Rev. 2016;96(4):1509–65. doi: 10.1152/physrev.00029.2015
Clive RT, Rudbeck L. Immunohistochemical Staining Methods. Education Guidebook. 6th ed. Dako Denmark A/S, An Agilent Technologies Company; 2013. 215 p.
Rasband W, Ferreire T. ImageJ user guide 1.48 v. National Institute of Health, USA, 2015. 140 p.
Hammer Ø. PAST: Paleontological Statistics, Version 3.06. Reference manual / Ø. Hammer // Oslo: Natural History Museum University of Oslo. – 2015. – 221p.
Manasova, G.S.; Shpak, I.V.; Didenkul, N.V.; Kuzmin, N.V.; Badiuk, N.S. On the effectivenessof a personalized approach in the prevention of calcitriol-associated complications of pregnancy and childbirth / PharmacologyOnLine; Archives - 2020 - vol. 3 - 270-278.
Downloads
Published
How to Cite
Issue
Section
License
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 254
Number of citations: 0
