Evaluation of the effectiveness of treatment of experimental postoperative peritonitis

Abstract

Purpose: to develop a new method of lavage of the abdominal cavity in the experimental conditions.

Materials and methods. In the experiment we use 40 rats Wistar line weighing 160-240 g, kept in a vivarium in compliance with all standards.

Research results and their discussion. During relaparotomy, we performed mechanical cleaning of the abdominal cavity from fecal masses, layers of fibrin, the abdominal cavity was washed twice with 100 ml of 0.02% decamethoxine solution at a temperature of 30-35 ° C. After removing the drug residues from the abdominal cavity, we pour 50 ml of Extranil peritoneal dialysis solution at a temperature of370C, the active substance of which is icodextrin, not glucose, ie it is not a nutrient medium for microorganisms, but has antimicrobial action due to hyperosmolarity and increases its adsorption properties.