Pathogenetic aspects of post-surgical adhesions prevention (review of literature)
DOI:
https://doi.org/10.12775/JEHS.2020.10.05.040Keywords
pathogenetic aspects, prevention, post-surgical adhesionsAbstract
Introduction. It has been established that adhesions in the abdominal cavity are a natural protective and adaptive reaction in response to peritoneal damage, but excessive adhesions are not only a pathological process, but also causes intestinal obstruction in children in 62%.
Purpose: to study the pathogenetic aspects of prevention of surgical adhesions.
Results. A large number of preventive strategies have been proposed, which are aimed at certain adhesion etiopathogenesis zones, such as inflammation and exudation reduction; coagulation cascade inhibition, fibrin matrix and fibrin deposition formation; fibrinolysis process potentiation; fibroblast proliferation inhibition; neoangiogenesis inhibition; free radical oxidation prevention caused by hypoxia; prevention of contact between damaged peritoneal areas.
Conclusions. The problem of prevention of excessive intra-abdominal adhesions remains relevant due to imperfection of the existing variety of methods of prevention and treatment of adhesive intestinal obstruction, and one of the main tasks of its solution in children is to find a sparing and, at the same time, effective way to prevent excessive intra-abdominal adhesions at preoperative, intraoperative and postoperative stages.
References
Beyene R.T., Kavalukas S.L., Barbul A. Intra-abdominal adhesions: Anatomy, physiology, pathophysiology, and treatment // Current Problems in Surgery. 2015. – Vol. 52. – P. 271–319. doi: 10.1067/j.cpsurg.2015.05.001.
Capella-Monsonís H., Kearns S., Kelly J., Zeugolis D.I. Battling adhesions: from understanding to prevention. // BMC Biomed Eng. – 2019. – Vol.1:5. Published 2019 Feb 27. doi:10.1186/s42490-019-0005-0
Kelli M. Braun. The biology of adhesion formation in the peritoneal cavity // Seminars in Pediatric Surgery. – 2014. – Vol. 23. – P. 336–343. DOI: 10.1053/j.sempedsurg.2014.06.004
Мельниченко М. Г., Квашніна А. А. Регенерація очеревини та патогенез формування післяопераційних перитонеальних спайок // Хірургія України. – 2019. – № 3. – С. 72-77. [Melnichenko M. G., Kvashnina A. A. Peritoneal regeneration and pathogenesis of postoperative peritoneal adhesions // Surgery of Ukraine. - 2019. - № 3. - P. 72-77]. DOI: http://doi.org/10.30978/SU2019-3-88
Fredriksson F., Christofferson R.H., Lilja H.E. Adhesive small bowel obstruction after laparotomy during infancy. // Br J Surg. – 2016. – Vol.103(3). – P. 284-9. doi: 10.1002/bjs.10072.
Okabayashi K., Ashrafian H., Zacharakis E., et al. Adhesions after abdominal surgery: a systematic review of the incidence, distribution and severity. // Surg Today. –2014. – Vol.44(3). – P. 405-420. doi:10.1007/s00595-013-0591-8
Fortin C.N., Saed Gh.M., Diamond M.P. Predisposing factors to post-operative adhesion development. // Human Reproduction Update. – 2015. – Vol.21, No 4. – P. 536–551. https://doi.org/10.1093/humupd/dmv021.
Кондратович Л.М. Основы понимания формирования спаечного процесса в брюшной полости. Интраоперационная профилактика противоспаечными барьерными препаратами (обзор литературы). // Вестник новых медицинских технологий. – 2014. – T. 21, No 3. – C. 169-172. DOI: 10.12737/5929. / Kondratovych L.M. Osnovy ponymanyia formyrovanyia spaechnoho protsessa v briushnoi polosty. Yntraoperatsyonnaia profylaktyka protyvospaechnymy barernymy preparatamy (Russian). // Vestnyk novykh medytsynskykh tekhnolohyi. – 2014. – Vol. 21, No 3. – P. 169-172.
Catena F., Di Saverio S., Coccolini F. et al. Adhesive small bowel adhesions obstruction: Evolutions in diagnosis, management and prevention. // World journal of gastrointestinal surgery. – 201. – Vol. 8. – P. 222–231. DOI: 10.4240/wjgs.v8.i3.222.
Broek R., Krielen P., Di Saverio S. et al. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group // World Journal of Emergency Surgery. – 2018. – Vol. 13. doi: 10.1186/s13017-018-0185-2.
Fredriksson, F., Engstrand, T., Christofferson, R.H., Bowden, T., Lilja, H.E. Sutures impregnated with an aldehyde-carbonyl scavenger reduce peritoneal adhesions. J Pediatr Surg. – 2017. – Vol. 52, No 11. – P. 1853-1858. doi: 10.1016/j.jpedsurg.2017.01.058.
Gomel V., Koninckx P.R. Microsurgical principles and postoperative adhesions: lessons from the past. // Fertil Steril. – 2016. – Vol. 106, No 5. – P. 1025-1031. doi: 10.1016/j.fertnstert.2016.08.040. PMID: 27692286.
Binda M. M. Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery // Archives Gynecology Obstetrics. – 2015. – Vol. 29. – P. 955–971. doi: 10.1007/s00404-015-3717-y.
Bamigboye A.A., Hofmeyr G. Closure versus non-closure of the peritoneum at caesarean section: short- and long-term outcomes. // Cochrane Database of Systematic Reviews. – 2014. – Issue 8. Art. No.: CD000163. DOI: 10.1002/14651858.CD000163.pub2
Cassidy M.R., Sheldon H.K., Gainsbury M.L., et al. The neurokinin 1 receptor regulates peritoneal fibrinolytic activity and postoperative adhesion formation. //J Surg Res. – 2014. – Vol. 191, No 1. – P. 12-18. doi: 10.1016/j.jss.2014.04.030
Cwaliński J., Bręborowicz A., Połubińska A. The Impact of 0.9% NaCl on Mesothelial Cells After Intraperitoneal Lavage During Surgical Procedures. // Advances in Clinical and Experimental Medicine. – 2016. – Vol. 25. – P. 1193–1198. doi: 10.17219/acem/44381.
Wu Y., Wei G., Yu J., et al. Danhong Injection Alleviates Postoperative Intra-abdominal Adhesion in a Rat Model. // Med Cell Longev. – 2019. – Vol. 19; 2019:4591384. doi: 10.1155/2019/4591384.
Lee M.T., Lee C.C., Wang H.M., Chou T.H., Wu M.C., Hsueh K.L., Chen S.C. Hypothermia increases tissue plasminogen activator expression and decreases post-operative intra-abdominal adhesion. // PLoS One. – 2016. – Vol. 11, No 9. e0160627. doi: 10.1371/journal.pone.0160627.
Wei G., Chen X., Wang G., Jia P., Xu Q., Ping G. Li X. Inhibition of cyclooxygenase-2 prevents intra-abdominal adhesions by decreasing activity of peritoneal fibroblasts. // Drug design, development and therapy. – 2015. – Vol. 9. – P. 3083–3098. doi:10.2147/DDDT.S80221
Ahmad G., Thompson M., Kim K., et al. Fluid and pharmacological agents for adhesion prevention after gynaecological surgery. // Cochrane Database Syst Rev. –2020. – Vol.7, No 7. CD001298. Published 2020 Jul 17. doi: 10.1002/14651858.CD001298.pub5
Lim R., Morrill J.M., Prushik S.G., et al. An FDA approved neurokinin-1 receptor antagonist is effective in reducing intraabdominal adhesions when administered intraperitoneally, but not orally. // J Gastrointest Surg. 2008. – Vol.12, No 10. – P. 1754-1761. doi:10.1007/s11605-008-0634-4
Jafari-Sabet M., Shishegar A., Saeedi A.R., Ghahari S. Pentoxifylline Increases Antiadhesion Effect of Streptokinase on Postoperative Adhesion Formation: Involvement of Fibrinolytic Pathway. // Indian J Surg. – 2015. – Vol.77, Suppl 3. – P. 837-842. doi:10.1007/s12262-013-1025-y
Wu W., Cheng R., das Neves J., et al. Advances in biomaterials for preventing tissue adhesion. // J Control Release. – 2017. – Vol. 261. – P. 318-336. doi: 10.1016/j.jconrel.2017.06.020
Chiorescu S., Andercou O., Grad N. O., Mironiuc I. A. Intraperitoneal administration of rosuvastatin prevents postoperative peritoneal adhesions by decreasing the release of tumor necrosis factor. // Clujul Medical. – 2018. – Vol.91. – P. 79–84. doi: 10.15386/cjmed-859.
Dinarvand P., Hassanian S. M., Weiler H., Rezaie A. R. Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation // Blood. – 2015. – Vol.125. – P. 1339–1348. doi: 10.1182/blood-2014-10-609339.
Atta H.M., Al-Hendy A., El-Rehany M.A., et al. Adenovirus-mediated over expression of human tissue plasminogen activator prevents peritoneal adhesion formation / reformation in rats. // Surgery. – 2009. – Vol. 146, No 1. – P. 12-17. doi: 10.1016/j.surg.2009.02.018
Weiss A., Sood D., Greenway S.E., Tomassi M. Value of gastrografin in adhesive small bowel obstruction // Langenbecks Arch Surg. – 2017. – Vol. 402(8). – P. 1233-1239. doi: 10.1007/s00423-017-1605-6.
Ahmad G., Kim K., Thompson M., et al. Barrier agents for adhesion prevention after gynaecological surgery. // Cochrane Database Syst Rev. – 2020. – Vol.3, No 3: CD000475. Published 2020 Mar 22. doi: 10.1002/14651858.CD000475.pub4
Cheong Y., Bailey S., Forbes J. Randomized Controlled Trial of Hyalobarrier® Versus No Hyalobarrier® on the Ovulatory Status of Women with Periovarian Adhesions: A Pilot Study. // Adv Ther. – 2017. – Vol.34, No 1. – P. 199-206. doi:10.1007/s12325-016-0453-z
Naito M., Ogura N., Yamanashi T., et al. Prospective randomized controlled study on the validity and safety of an absorbable adhesion barrier (Interceed®) made of oxidized regenerated cellulose for laparoscopic colorectal surgery. // Asian J Endosc Surg. – 2017. – Vol.10, No 1. – P. 7-11. doi:10.1111/ases.12334
Ten Broek R.P.G., Stommel M.W.J., Strik C., van Laarhoven C.J.H.M., Keus F., van Goor H. Benefits and harms of adhesion barriers for abdominal surgery: a systematic review and meta-analysis. // Lancet. – 2014. – Vol.383, No 9911. – P. 48-59. doi:10.1016/S0140-6736(13)61687-6
Downloads
Published
How to Cite
Issue
Section
License
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 493
Number of citations: 0
