Experimental rationale and clinical use of radiowave energy, anti-adhesion drugs, placenta cryoextract, range of physiotherapy measures and assisted reproductive technology in the restoration of reproductive function of patients who underwent operative in
Keywordstubal pregnancy, reproductive function, radiowave energy, adhesion process, anti-adhesion barrier, physiotherapy treatment
The aim: to increase the effectiveness of reproductive health restoration in women with progressive tubal pregnancy and develop new approaches to improving methods of restoring reproductive function in patients using endoscopy, anti-adhesive drugs, placental cryoextract, physiotherapy and ART. To substantiate the use of radio wave energy, anti-adhesive drugs, placental cryoextract, an experiment was performed on 196 mature female Wistar rats and 90 BALB / s mice. An analysis of clinical observations of 518 women. The control group included 60 healthy women, 458 patients with tubal pregnancy were divided into 2nd (152 patients), 3rd (154 patients) and 4th (152 patients) clinical groups in which different methods of treatment and rehabilitation of reproductive function were used.
It was proved that the use in the 2 clinical group patients PEO with CMC, streptodornase with streptokinase reduced the occurrence of adhesion at 1.6 times, use in patients 3 of the clinical group PEO with CMC, streptodornase with streptokinase and placenta cryoextract led to decrease occurrence of adhesions 2.2 times (p <0.05), use in the 4th clinical group patients sodium hyaluronate, streptodornase with streptokinase and placenta cryoextract helped to reduce the occurence of adhesions by 2.6 times (p < 0.05) compared with the detected intraoperativly adhesion process. The inclusion of ART methods in the treatment of patients who did not become pregnant contributed to the onset of uterine pregnancy in 64.9 - 75.7% of the patients under examination.
Nicole Yoder, Reshef Tal, J Ryan Martin. Abdominal Ectopic Pregnancy After in Vitro Fertilization and Single Embryo Transfer: A Case Report and Systematic Review. Reprod Biol Endocrinol, 14 (1), 69. 2016 Oct 19. DOI: 10.1186/s12958-016-0201-x
Sun F, Yang S, Yang Y, Liu X, Xu H. Laparoscopic Management of 42 Cases of Tubal Stump Pregnancy and Postoperative Reproductive Outcomes.J Minim Invasive Gynecol. 2019 Nov 12. pii: S1553-4650(19)31289-0. doi: 10.1016/j.jmig.2019.04.030. [Epub ahead of print]
ACOG Practice Bulletin No. 193: Tubal Ectopic Pregnancy: CorrectionObstet Gynecol. 2019 May;133(5):1059. doi: 10.1097/AOG.0000000000003269
Санов ИА, Чунихина НА. Оптимизация лечения трубной беременности с применением селективной лазеротерапии //Мать и дитя. – 2014.- C. 321-322 [Sanov IA, Chunikhina NA. Optimization of treatment of tubal pregnancy using selective laser therapy // Mother and Child. - 2014.- C. 321-322]
Матвеев АМ, Новикова ВА, Федорович ОК. Возможности сохранения и восстановления фертильности после хирургического лечения трубной беременности гинекология. –Москва: Медицинское маркетинговое агентство "МедиаМедика", 2016 [Matveev AM, Novikova VA, Fedorovich OK. Possibilities of preserving and restoring fertility after surgical treatment of tubal pregnancy gynecology. –Moscow: Medical Marketing Agency "MediaMedica", 2016]
Jourdain O, Hopirtean V, Saint-Amand H. Fertility after laparoscopic treatment of ectopic pregnancy in a series of 138 patients. J Gynecol Obstet Biol Reprod. 2010; 30(3): 265-271.
How to Cite
LicenseThe periodical offers access to content in the Open Access system under the Creative Commons non-exclusive license (CC BY-ND 4.0).
Number of views and downloads: 6
Number of citations: 0