Dental status changes in patients with ischemic heart disease and the ways of its normalization
DOI:
https://doi.org/10.12775/JEHS.2020.10.02.022Keywords
inflammation, periodontitis, coronary heart disease, oral liquidAbstract
Aim: increasing the effectiveness of treatment of periodontal disease in patients with ischemic heart disease
Materials and methods. The oral cavity was examined and the clinical course features of chronic periodontitis were studied in patients with ischemic heart disease Determing dental, hygienic index and biochemical indices in oral liquid (elastase, MDA, urease, lysozyme, catalase). The “Apifil” and “Asepta” were used by oral rinsing.
Results. The patients with ischemic heart disease have a worse state of oral cavity, compared to those who do not suffer from ischemic heart disease. The determined periodontal indexs provided evidence of a significantly higher activity of the dystrophic and inflammatory changes of periodontal tissues in the patients with ischemic heart disease. The oral cavity liquid levels of elastase, urease were raised, but levels of catalase and lusozyme were reduced in patients with ischemic heart disease Oral rinsing of “Apifil” and “Asepta” were reduced the levels of elastase, urease and dental indices but were raised the levels of lysozyme and catalase.
Conclusions. The rinse “Apifil” render the stomatoprotective action on patients with ischemic heart disease.
References
Sokhova I.A. Osobennosti stomatologicheskogo statusa paczientov s ishemicheskoj bolezn`yu serdcza [Features of the dental status of patients with coronary heart disease]. Sb. Klinicheskaya mediczina. 2015;4:41-46.
Karimov B.M. Rol` obshhesomaticheskogo statusa v razvitii vospalitel`no-destruktivny`kh porazhenij parodonta [The role of somatic status in the development of inflammatory and destructive lesions of periodontal]. Vestnik Aviczenny, 2015;1(58):115-119.
Van der Bil` P. Vzaimosvyaz` zabolevanij parodonta i serdechno-sosudistoj sistemy` [The relationship of periodontal disease and the cardiovascular system]. Problemy` stomatologii. 2014; 6: 4-8.
Skochko O.V. Vzaimosvyaz` zabolevanij parodonta s faktorami riska razvitiya ishemicheskoj bolezni serdcza / [The relationship of periodontal disease with risk factors for coronary heart disease]. Ukrainskij kardiologicheskij zhurnal. 2015;2:87-94.
Mishhenko I.S. Bolezni parodonta [Periodontal Disease]. Dnepropetrovsk: Kolo. 2003: 272.
Patent na korisnu model` 129913 Ukrayina MPK (2018.01) A61K31/19, A61K897 Opoli`skuvach rotovoyi porozhnini dlya mi`sczevoyi profi`laktiki ta li`kuvannya zapal`nikh zakhvoryuvan` tkanin slizovoyi obolonki [Oral rinse for local prevention and treatment of inflammatory diseases of the mucous membranes]. Kravchenko L.S., Fi`zor N.S.; zayavnik i` patentovlasnik ONMedU – zayav. u201801440 vi`d 14.02.2018, opub. 26.11.2018, Byul. 22.
Leviczkij A.P. Salivacziya u zdorovy`kh licz raznogo vozrasta i stomatologicheskikh bol`ny`kh [Salivation in healthy individuals of different ages and dental patients]. Vi`snik stomatologi`yi. 2005;2:7-8.
Lowry O.H. Protein measurement with Folin phenol reagent. Biol. Chem. 1951;193:265-275.
Stal`naya I. D. Metod opredeleniya malonovogo dial`degida s pomoshh`yu tiobarbiturovoj kisloty [Method for determination of malondialdehyde using thiobarbituric acid]. Sovremenny`e metody` v biokhimii. M. Mediczina. 1977:66-68.
Leviczkij A.P. Metody` opredeleniya aktivnosti e`lastazy` i eyo ingibitorov [Methods for determining the activity of elastase and its inhibitors]. Kiev: GFCz, 2002: 15.
Gavrikova L.M. Ureaznaya aktivnost` rotovoj zhidkosti u bol`ny`kh s ostroj i odontogennoj infekcziej chelyustno-liczevoj oblasti /L.M. Gavrikova, I.T. Sechen` [Urea activity of oral fluid in patients with acute and odontogenic infection of the maxillofacial region]. Stomatologiya (Speczvy`pusk). 1996:.49-50.
Girin S.V. Modifikacziya metoda opredeleniya aktivnosti katalazy` v biologicheskikh substratakh [Modification of the method for determining the activity of catalase in biological substrates]. Laboratornaya diagnostika. 1999;4:45-46.
Leviczkij A.P. Lizoczim vmesto antibiotikov [Lysozyme instead of antibiotics]. Odessa: KP OGT, 2005: 74.
Visnovok derzhavnoyi sani`tarno-epi`demi`ologi`chnoyi ekspertizi derzhavnoyi sluzhbi Ukrayini z pitan` bezpechnosti` kharchovikh produkti`v ta zakhistu spozhivachi`v «Opoli`skuvach dlya porozhnini rota «Api`fi`l» [Opinion of the State Sanitary and Epidemiological Expertise of the Civil Service of Ukraine on Food Safety and Consumer Protection "Apifil Oral Rinse] № 602-123-20-1/36502 vi`d 28.08.2018.
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