Humanities
Skip to main content Skip to main navigation menu Skip to site footer
  • Register
  • Login
  • Menu
  • Home
  • Current
  • Archives
  • Announcements
  • About
    • About the Journal
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Register
  • Login

Journal of Education, Health and Sport

The effect of thiotriazoline on impaired immune system in experimental pneumonia and contact dermatitis
  • Home
  • /
  • The effect of thiotriazoline on impaired immune system in experimental pneumonia and contact dermatitis
  1. Home /
  2. Archives /
  3. Vol. 9 No. 12 (2019) /
  4. Research Articles

The effect of thiotriazoline on impaired immune system in experimental pneumonia and contact dermatitis

Authors

  • M. M. Regeda-Furdychko Lviv Medical Institute

DOI:

https://doi.org/10.12775/JEHS.2019.09.12.032

Keywords

contact dermatitis, pneumonia, immune system, thiotriazoline

Abstract

Literary sources indicate that various pathological processes are accompanied by the development of a violation of the immune system.

The aim of the study was to determine the pathogenetic justification for the use of thiotriazoline on the basis of immune system disorders in experimental pneumonia (EP) and contact dermatitis (CD).The researches were carried out on 55 guinea-pigs. The study material was collected on the 4th, 8th, 10th and 18th days of EP and ECD under ether anesthesia. EP was called by the method of VN Shlyapnikov, TL Solodov. ECD was simulated by method of VA Volkovoj. The content of T and B lymphocytes in the blood was determined by the method of Chernushenko KF, Kogosova LS, and the level of the circulating immune complexes (CIC) by the method of V. Haskova, J. Kaslik. We have established a gradual increase in the level of B-lymphocytes and CIC against the background of a decrease in T-lymphocytes in the blood on the 4th, 8th, 10th and 18th days of the development of EP and CD, with a predominance on the 18th day of the experiment before treatment. The use of thiotriazoline caused an immunocorrective effect in CD and EP.

References

Bondarchuk VI Changes in endogenous intoxication and humoral immunity under the influence of different types of inflammatory reaction of animals with gastroduodenitis. Bulletin of Scientific Research, 2015. №3. Pp. 107-109.

Volkova VA Study of the therapeutic efficacy of a new ointment with a lipophilic complex of aspen bark "Tremulin" under conditions of non-allergic contact dermatitis in rats. Pharmacology and drug toxicology. 2010. P.7-12.

Ferenc NM, Yurevich VR The role of lipid peroxidation processes and antioxidant defense system in the liver in the pathogenesis of experimental pneumonia and immobilization stress and correction of their disorders by corvitin. Medical chemistry. 2015. T.17. № 4 (62). Pp. 10 –103.

Shlyapnikov VN, Solodova TL Experimental models of acute pneumonia caused by opportunistic bacteria and their associations: Method. recommendations .: Saratov Medical Institute, 1988. 33 p.

Chernushenko E.F., Immunological Studies in Clinic/ EF Chernushenko, L.S. // Kohosova Kiev - Health. - 1978. - p.20.

Haskova V., Kaslik J., Matejckava M. Novy zpusob stanoveni circulujicich imunokomplexy w lidskych serech. Cas. Lek. Ces. 1977. T. 116, № 14. P. 436–437.

Tramper – Stranders G.A. Childhood community – acquired pneumonia: a review of etiology and antimicrobial treatment studies. Paediatr Respir. Rev. 26 (2018). P. 41-48.

Downloads

  • PDF

Published

2019-12-28

How to Cite

1.
REGEDA-FURDYCHKO, M. M. The effect of thiotriazoline on impaired immune system in experimental pneumonia and contact dermatitis. Journal of Education, Health and Sport. Online. 28 December 2019. Vol. 9, no. 12, pp. 320-324. [Accessed 6 July 2025]. DOI 10.12775/JEHS.2019.09.12.032.
  • ISO 690
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

Issue

Vol. 9 No. 12 (2019)

Section

Research Articles

License

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

Stats

Number of views and downloads: 462
Number of citations: 0

Search

Search

Browse

  • Browse Author Index
  • Issue archive

User

User

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians

Newsletter

Subscribe Unsubscribe

Tags

Search using one of provided tags:

contact dermatitis, pneumonia, immune system, thiotriazoline
Up

Akademicka Platforma Czasopism

Najlepsze czasopisma naukowe i akademickie w jednym miejscu

apcz.umk.pl

Partners

  • Akademia Ignatianum w Krakowie
  • Akademickie Towarzystwo Andragogiczne
  • Fundacja Copernicus na rzecz Rozwoju Badań Naukowych
  • Instytut Historii im. Tadeusza Manteuffla Polskiej Akademii Nauk
  • Instytut Kultur Śródziemnomorskich i Orientalnych PAN
  • Instytut Tomistyczny
  • Karmelitański Instytut Duchowości w Krakowie
  • Ministerstwo Kultury i Dziedzictwa Narodowego
  • Państwowa Akademia Nauk Stosowanych w Krośnie
  • Państwowa Akademia Nauk Stosowanych we Włocławku
  • Państwowa Wyższa Szkoła Zawodowa im. Stanisława Pigonia w Krośnie
  • Polska Fundacja Przemysłu Kosmicznego
  • Polskie Towarzystwo Ekonomiczne
  • Polskie Towarzystwo Ludoznawcze
  • Towarzystwo Miłośników Torunia
  • Towarzystwo Naukowe w Toruniu
  • Uniwersytet im. Adama Mickiewicza w Poznaniu
  • Uniwersytet Komisji Edukacji Narodowej w Krakowie
  • Uniwersytet Mikołaja Kopernika
  • Uniwersytet w Białymstoku
  • Uniwersytet Warszawski
  • Wojewódzka Biblioteka Publiczna - Książnica Kopernikańska
  • Wyższe Seminarium Duchowne w Pelplinie / Wydawnictwo Diecezjalne „Bernardinum" w Pelplinie

© 2021- Nicolaus Copernicus University Accessibility statement Shop