Characteristic of individual indicators of phagocytic activity of leukocytes under conditions of formation of experimental contact dermatitis and experimental pneumonia and the effect of the drug thiotriazoline
Keywordscontact dermatitis, pneumonia, polymorho-nuclear leucocytes, nonspecific resistance, thiotriazoline
AbstractThe work demonstrated, that polymorho-nuclear leucocytes take an active part in formation of experimental contact dermatitis and experimental pneumonia before and after administration of the antioxidant thiotriazoline and also testify to metabolic processes stimulation in leucocytes.
The immune-modulating thiotriazoline preparation application, beginning from 8 th day of the experiment, and during 10 days, showed the renewal of indexes of phagocytar leucocytes' activity, the test of nitroblue tetrasolium, what testifies to its corregating action – on nonspecific resistance condition.
Volkova V.A., Kuchynska I.V., Tiupka T.I. Study of the therapeutic efficacy of a new ointment with a lipophilic complex of the Tremulin aspen bark under conditions of non-allergic contact dermatitis in rats. Pharmacology and drug toxicology. 2010;7–12.
Shlyapnykov V.N., Solodova T.L. et al. Eksperimentalnye modeli ostrykh pnevmoniy, vyzvanykh uslovno-patolohicheskimi bakteriyami I ikh assotsiatsiey: metod. ukazaniya sost. Saratov, 1998. 30 p.
Gembitsky EV. Assessment of the immune status of the organism in medical establishments of the Soviet army and navy: Methodical manual. - Central Military Medical Directorate of the USSR Defense Ministry.1987. 114.
Menshikov VV. Laboratory research methods in the clinic. M. Medicine.1987. p. 310-311.
Beeckman D., Campbell J., Chimentгo D. et al. Proceedings of the Global IAD Expert Panel. Incontinence associated dermatitis: moving prevention forward. Wounds International. 2015. 21 p
Tramper-Stranders G.A. Childhood community-acquired pneumonia: a review of etiology and antimicrobial treatment studies. Paediatr Respir Rev, 26 (2018), pp. 41-48
How to Cite
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Number of views and downloads: 67
Number of citations: 0