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Journal of Education, Health and Sport

ROTEM and Standard Coagulation Tests in Patients with Polytrauma and Traumatic Brain Injury: Potential for Early Diagnosis of Trauma-Induced Coagulopathy
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  • ROTEM and Standard Coagulation Tests in Patients with Polytrauma and Traumatic Brain Injury: Potential for Early Diagnosis of Trauma-Induced Coagulopathy
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  3. Vol. 94 (2026) /
  4. Medical Sciences

ROTEM and Standard Coagulation Tests in Patients with Polytrauma and Traumatic Brain Injury: Potential for Early Diagnosis of Trauma-Induced Coagulopathy

Authors

  • O. Tarabrin International University

DOI:

https://doi.org/10.12775/JEHS.2026.94.75594

Keywords

polytrauma, traumatic brain injury, trauma-induced coagulopathy, ROTEM, standard coagulation tests, hemostasis, hemorrhagic shock, viscoelastic testing

Abstract

Background. Trauma-induced coagulopathy is a common complication of severe polytrauma and may adversely affect the clinical course of traumatic brain injury. Early identification of the underlying hemostatic abnormalities is essential for selecting patient-oriented hemostatic and transfusion strategies.

Objective. To compare the diagnostic capabilities of standard coagulation tests and rotational thromboelastometry in patients with polytrauma complicated by traumatic brain injury.

Results. Standard coagulation tests assess individual components of plasma-based hemostasis, whereas ROTEM provides a dynamic a

 

ssessment of clot formation, clot strength, and fibrinolysis. The main ROTEM parameters include CT, CFT, MCF, FIBTEM, and LI30. Viscoelastic testing may be useful for the rapid functional assessment of hemostasis and for guiding targeted transfusion strategies.

Conclusions. ROTEM and standard coagulation tests are not fully interchangeable. In patients with polytrauma, these methods should be used in combination, taking into account the clinical presentation, severity of bleeding, and hemodynamic status.

References

Shevchenko M. A., Stelmakh R. P. The use of ROTEM in clinical diagnostics of coagulopathy: analysis of possibilities and limitations. Current issues of modern medicine.2021;15(3):103–108.

2. Brohi K, Cohen MJ, Davenport RA. Acute coagulopathy of trauma: Mechanism, identification and effect. Current Opinion in Critical Care. 2013;19(6):551–557. DOI: 10.1097/MCC.0000000000000021.

3. Gomez-Builes C, Nardi M, Cohen MJ. Viscoelastic testing in trauma: An update. Current Opinion in Critical Care. 2020;26(6):613–619. DOI: 10.1097/MCC.0000000000000765.

4. Schöchl H, Solomon C, Schlimp CJ. Trauma bleeding management: The concept of goal-directed primary care using viscoelastic point-of-care testing. Frontiers in Medicine. 2014;1:15. DOI: 10.3389/fmed.2014.00015.

5. Davenport RA, Brohi K. Coagulopathy in trauma patients: Importance of early recognition and management. British Journal of Anaesthesia. 2013;111(1):3–12. DOI: 10.1093/bja/aet089.

6. Chen Y, Zhao Y, Wang H. Coagulation and fibrinolysis disorders in trauma patients: From mechanisms to management. International Journal of Molecular Sciences. 2023;24(8):7132. DOI: 10.3390/ijms24087132.

7. Filyk OV, Vyshynska MB. Hemostasis and inflammation in patients with polytrauma. EMERGENCY MEDICINE. 2021;17(8).

8. Alam HB, Rhee P. New developments in hemorrhagic shock. Current Opinion in Critical Care. 2021;27(6):600–606. DOI: 10.1097/MCC.0000000000000871.

9. White NJ, Martin EJ, Brophy DF, Ward KR. Coagulopathy and traumatic shock: Hemostatic function during the critical period before resuscitation. Resuscitation. 2010;81(1):111–116. DOI: 10.1016/j.resuscitation.2009.09.017.

10. White NJ, Ward KR, Pati S, Strandenes G, Cap AP. Hemorrhagic blood failure: Oxygen debt, coagulopathy, and endothelial damage. Journal of Trauma and Acute Care Surgery. 2014;77(6):S147–S155. DOI: 10.1097/TA.0000000000000348.

11. Zlenko AM, Leshchenko IS. Neuroprotection in anesthesiology for severe TBI. Ukrainian Medical Almanac. 2023;26(1):73–78.

12. Doroshenko S. Yu., Tkachenko O. M. The choice of anesthetics in patients with traumatic brain injury. Surgery and Anesthesiology. 2022;12(3):29–34.

Journal of Education, Health and Sport

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Published

2026-07-27

How to Cite

1.
TARABRIN, O. ROTEM and Standard Coagulation Tests in Patients with Polytrauma and Traumatic Brain Injury: Potential for Early Diagnosis of Trauma-Induced Coagulopathy. Journal of Education, Health and Sport. Online. 27 July 2026. Vol. 94, p. 75594. [Accessed 17 September 2026]. DOI 10.12775/JEHS.2026.94.75594.
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Issue

Vol. 94 (2026)

Section

Medical Sciences

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Copyright (c) 2026 O. Tarabrin

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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