FIBTEM Parameters as Surrogate Markers of Hypofibrinogenemia in Acute Polytrauma
DOI:
https://doi.org/10.12775/JEHS.2026.87.74875Keywords
Polytrauma, bleeding, thromboelastography, hemostasis, acute trauma, hemorrhageAbstract
Introduction. According to the World Health Organization (WHO), injuries and violence cause approximately 4.4 million deaths worldwide each year and account for nearly 8% of all deaths; among people aged 5–29 years, injuries are among the leading causes of mortality. Hypofibrinogenemia is one of the key components of early trauma-induced coagulopathy and is associated with impaired hemostasis and an increased risk of massive bleeding. This review was based on an analysis of international guidelines, original clinical studies, and recent review publications addressing viscoelastic monitoring, FIBTEM, and fibrinogen-targeted therapy in trauma. Results. FIBTEM enables rapid assessment of fibrin-dependent clot strength, while its A5, A10, and MCF parameters demonstrate an acceptable correlation with fibrinogen levels measured by the Clauss method in trauma patients. Conclusions. FIBTEM is a clinically important tool for the early dete ction of hypofibrinogenemia and can be integrated into goal-directed algorithms for hemostatic resuscitation.References
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