The correlation between tuberculosis and diabetes incidence and the impact of mass migration on the development of tuberculosis and drug-resistant tuberculosis on the example of India and England

Abstract

Introduction: Tuberculosis is still a major health concern around the world, especially in developing countries with very large populations. Diabetes may be responsible for the progression of Mycobacterium tuberculosis infection. According to the research of some authors, the development of an active form of tuberculosis is associated with the earlier development of diabetes, which is called the epidemic of the 21st century due to the very large number of patients around the world and worrying predictions of the incidence of diabetes for the upcoming years. Diabetes May also predispose to drug-resistant tuberculosis as well as worse and slower anti-tuberculosis treatment effects. In European countries where the prevalence of drug-resistant and TB is Lower than in developing countries, most cases of tuberculosis have been reported among immigrants. The aim of the study is to analyze the current epidemiological situation of tuberculosis, multi-drug resistant tuberculosis and diabetes in Great Britain (with particular attention directed to England) and in India in correlation with the influx of migrants from India to Great Britain. Materials and method: The data used in this analysis come from the Global Tuberculosis Reports published by The World Health Organization and National Diabetes Audit Reports published by The Health and Social Care Information Center, as well as from Rother publications made available in 2001-2019. Results: There has been a significant increase in the incidence of diabetes in England and India in recent years, the incidence of tuberculosis in England Has been decreasing, while in India it Has remained more or less stable. An increase in the incidence of drug-resistant tuberculosis was observed in the population of India and in the population of migrants of Hindu origin in England, while the Total number of MDR cases in England Romains more or less stable with a downward trend in 2011-2014 and slightly rising in 2015-2017. Conclusions: Due to the strong association between diabetes and tuberculosis, the probable association of diabetes and multi-drug resistant tuberculosis, and the increasing incidence of diabetes, the control of TB incidence may be disturbed, and there is a risk of an increase in the incidence of MDR tuberculosis. This phenomenon can threaten not only developing countries, where tuberculosis is more common than in other regions of the world, but also highly developer countries that akcept large numbers of migrants.