Humanities
Skip to main content Skip to main navigation menu Skip to site footer
  • Register
  • Login
  • Menu
  • Home
  • Current
  • Archives
  • Announcements
  • About
    • About the Journal
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Register
  • Login

Journal of Education, Health and Sport

The Tattoos and the risk of health complications: a narrative review: Narrative review
  • Home
  • /
  • The Tattoos and the risk of health complications: a narrative review: Narrative review
  1. Home /
  2. Archives /
  3. Vol. 95 (2026) /
  4. Medical Sciences

The Tattoos and the risk of health complications: a narrative review

Narrative review

Authors

  • Alicja Nierychlewska Nicolaus Copernicus Hospital, Copernicus PL Sp. z o.o., Gdańsk, Poland https://orcid.org/0009-0009-6783-4601
  • Michał Falis University Clinical Center of Gdańsk, Gdańsk, Poland https://orcid.org/0009-0002-1074-6036
  • Alicja Solecka University Clinical Center of Gdańsk, Gdańsk, Poland https://orcid.org/0009-0001-0688-309X
  • Agata Bronisławska Nicolaus Copernicus Hospital, Copernicus PL Sp. z o.o., Gdańsk, Poland https://orcid.org/0009-0003-3833-0638
  • Robert Bronisławski Nicolaus Copernicus Hospital, Copernicus PL Sp. z o.o., Gdańsk, Poland https://orcid.org/0009-0004-6494-4307
  • Damian Stencelewski University Clinical Center of Gdańsk, Gdańsk, Poland https://orcid.org/0009-0002-7359-5562
  • Laura Magdalena Sikorska St. Vincent de Paul Municipal Hospital in Gdynia, Gdynia, Poland https://orcid.org/0009-0009-5326-779X
  • Magdalena Aleksandra Boniecka St. Vincent de Paul Municipal Hospital in Gdynia, Gdynia, Poland https://orcid.org/0009-0008-6941-1859
  • Michalina Grudzińska Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland https://orcid.org/0009-0000-0687-3089

DOI:

https://doi.org/10.12775/JEHS.2026.95.73995

Keywords

tattoo, health complications, tattoo ink, allergic reactions, pigment migration

Abstract

Introduction: As tattooing has become a widespread form of body modification, concerns about its health safety have grown. Tattoo inks are mixtures of organic pigments and metal compounds whose toxicological profile after intradermal application remains incompletely understood.

Aim: The aim of this review was to summarise the current knowledge on the health complications of tattooing, spanning dermatological, infectious, pigment-migration and oncological aspects. A second objective was to assess the quality of the available evidence.

Material and method: A narrative review of English-language literature indexed in PubMed and Google Scholar up to December 2025 was performed, including original studies, reviews, case reports and regulatory documents.

Results: Cutaneous complications are best documented - early inflammatory, infectious and allergic reactions, chronic allergy (mainly to red pigment), granulomatous and sarcoidal changes, photo-induced reactions and adverse effects of laser removal. Blood-borne transmission (HBV, HCV, HIV) is linked mainly to non-professional settings; HPV, HSV and rare infective endocarditis also occur. Pigment particles, metals and titanium dioxide may migrate to regional lymph nodes, with scarce data on systemic distribution. Lymphoma findings are divergent and skin cancers within tattoos appear incidental.

Conclusions: Most complications are cutaneous and mild; serious systemic and oncological consequences are rare and not confirmed as direct effects. The main gaps concern ink toxicology and long-term pigment migration, justifying further research, improved regulation and high hygienic and diagnostic standards.

References

1. Kluger N. Epidemiology of Tattoos in Industrialized Countries. In: Serup J, Kluger N, Bäumler W, eds. Current Problems in Dermatology. Vol 48. S. Karger AG; 2015:6-20. doi:10.1159/000369175

2. Interactive H. One in Five U.S. Adults Now Has a Tattoo. Accessed July 1, 2026. https://www.prnewswire.com/news-releases/one-in-five-us-adults-now-has-a-tattoo-140123523.html

3. More Americans Have Tattoos Today than Seven Years Ago | Ipsos. August 29, 2019. Accessed July 1, 2026. https://www.ipsos.com/en-us/news-polls/more-americans-have-tattoos-today

4. Jaworska K, Fijałkowska M, Antoszewski B. Tattoos yesterday and today in the Polish population in the decade 2004–2014. Health Psychology Report. 2018;6(4):321-329. doi:10.5114/hpr.2019.77175

5. Klügl I, Hiller KA, Landthaler M, Bäumler W. Incidence of Health Problems Associated with Tattooed Skin: A Nation-Wide Survey in German-Speaking Countries. Dermatology. 2010;221(1):43-50. doi:10.1159/000292627

6. Grant CA, Twigg PC, Baker R, Tobin DJ. Tattoo ink nanoparticles in skin tissue and fibroblasts. Beilstein J Nanotechnol. 2015;6:1183-1191. doi:10.3762/bjnano.6.120

7. Schreiver I. Tattoo Pigments: Biodistribution and Toxicity of Corresponding Laser Induced Decomposition Products. Freie Universität Berlin. Preprint posted online 2018:151 Seiten. doi:10.17169/REFUBIUM-14359

8. Giulbudagian M, Schreiver I, Singh AV, Laux P, Luch A. Safety of tattoos and permanent make-up: a regulatory view. Arch Toxicol. 2020;94(2):357-369. doi:10.1007/s00204-020-02655-z

9. Laux P, Tralau T, Tentschert J, et al. A medical-toxicological view of tattooing. The Lancet. 2016;387(10016):395-402. doi:10.1016/S0140-6736(15)60215-X

10. Serup J, Hutton Carlsen K, Sepehri M. Tattoo Complaints and Complications: Diagnosis and Clinical Spectrum. In: Serup J, Kluger N, Bäumler W, eds. Current Problems in Dermatology. Vol 48. S. Karger AG; 2015:48-60. doi:10.1159/000369645

11. Islam PS, Chang C, Selmi C, et al. Medical Complications of Tattoos: A Comprehensive Review. Clinic Rev Allerg Immunol. 2016;50(2):273-286. doi:10.1007/s12016-016-8532-0

12. Weiß KT, Schreiver I, Siewert K, et al. Tattoos – more than just colored skin? Searching for tattoo allergens. J Deutsche Derma Gesell. 2021;19(5):657-669. doi:10.1111/ddg.14436

13. Shao CG, Casterline BW, Martin KL. Tattoo-induced allergic contact dermatitis presents diagnostic challenge as a cellulitis mimic. The American Journal of Emergency Medicine. 2024;77:234.e1-234.e3. doi:10.1016/j.ajem.2023.12.016

14. Tramontana M, Hansel K, Bianchi L, Sensini C, Malatesta N, Stingeni L. Advancing the understanding of allergic contact dermatitis: from pathophysiology to novel therapeutic approaches. Front Med. 2023;10:1184289. doi:10.3389/fmed.2023.1184289

15. Kaur RR, Kirby W, Maibach H. Cutaneous allergic reactions to tattoo ink. J of Cosmetic Dermatology. 2009;8(4):295-300. doi:10.1111/j.1473-2165.2009.00469.x

16. Aberer W, Snauwaert JE, Render UM. Allergic Reaction to Pigments and Metals. In: Cuyper CD, Pérez-Cotapos S ML, eds. Dermatologic Complications with Body Art. Springer Berlin Heidelberg; 2009:61-89. doi:10.1007/978-3-642-03292-9_6

17. Simunovic C, Shinohara MM. Complications of Decorative Tattoos: Recognition and Management. Am J Clin Dermatol. 2014;15(6):525-536. doi:10.1007/s40257-014-0100-x

18. Pérez-Cotapos S. ML, De Cuyper C, Cossio L. Tattooing and Scarring: Technique and Complications. In: Cuyper CD, Pérez-Cotapos S ML, eds. Dermatologic Complications with Body Art. Springer Berlin Heidelberg; 2009:29-41. doi:10.1007/978-3-642-03292-9_3

19. Bose R, Sibley C, Fahim S. Granulomatous and systemic inflammatory reactions from tattoo ink: Case report and concise review. SAGE Open Medical Case Reports. 2020;8:2050313X20936036. doi:10.1177/2050313X20936036

20. Antonovich DD, Callen JP. Development of Sarcoidosis in Cosmetic Tattoos. Arch Dermatol. 2005;141(7). doi:10.1001/archderm.141.7.869

21. Hutton Carlsen K, Serup J. Photosensitivity and photodynamic events in black, red and blue tattoos are common: A ‘Beach Study.’ Acad Dermatol Venereol. 2014;28(2):231-237. doi:10.1111/jdv.12093

22. Bjornberg A. Reactions to Light in Yellow Tattoos From Cadmium Sulfide. Arch Dermatol. 1963;88(3):267. doi:10.1001/archderm.1963.01590210025003

23. De Cuyper C, D’hollander D. Materials Used in Body Art. In: Cuyper CD, Pérez-Cotapos S ML, eds. Dermatologic Complications with Body Art. Springer Berlin Heidelberg; 2009:13-28. doi:10.1007/978-3-642-03292-9_2

24. Bäumler W, Weiß KT. Laser assisted tattoo removal – state of the art and new developments. Photochem Photobiol Sci. 2019;18(2):349-358. doi:10.1039/c8pp00416a

25. Ferguson JE, Andrew SM, Jones CJ, August PJ. The Q-switched neodymium:YAG laser and tattoos: a microscopic analysis of laser-tattoo interactions. Br J Dermatol. 1997;137(3):405-410.

26. Hauri U, Hohl C. Photostability and Breakdown Products of Pigments Currently Used in Tattoo Inks. In: Serup J, Kluger N, Bäumler W, eds. Current Problems in Dermatology. Vol 48. S. Karger AG; 2015:CLXXIV-CLXXIX. doi:10.1159/000369225

27. Korabiusz K, Wawryków A, Fabian - Danielewska A, et al. Laser removal of tattoo- a case report. Published online June 24, 2019. doi:10.5281/ZENODO.3253463

28. Dieckmann R, Boone I, Brockmann SO, et al. The Risk of Bacterial Infection After Tattooing. Deutsches Ärzteblatt international. Published online October 7, 2016. doi:10.3238/arztebl.2016.0665

29. Falsey RR, Kinzer MH, Hurst S, et al. Cutaneous Inoculation of Nontuberculous Mycobacteria During Professional Tattooing: A Case Series and Epidemiologic Study. Clinical Infectious Diseases. 2013;57(6):e143-e147. doi:10.1093/cid/cit347

30. Lim SH, Lee S, Lee YB, et al. Increased prevalence of transfusion-transmitted diseases among people with tattoos: A systematic review and meta-analysis. Khan MR, ed. PLoS ONE. 2022;17(1):e0262990. doi:10.1371/journal.pone.0262990

31. Tohme RA, Holmberg SD. Transmission of Hepatitis C Virus Infection Through Tattooing and Piercing: A Critical Review. Clinical Infectious Diseases. 2012;54(8):1167-1178. doi:10.1093/cid/cir991

32. Foerster M, Zins M, Goldberg M, et al. Tattoo practices and risk of hepatitis B and hepatitis C infection in the French Constances study. International Journal of Infectious Diseases. 2026;163:108288. doi:10.1016/j.ijid.2025.108288

33. Lavanchy D. Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention. Journal of Clinical Virology. 2005;34:S1-S3. doi:10.1016/S1386-6532(05)00384-7

34. Cohen PR. Tattoo-Associated Viral Infections: A Review. CCID. 2021;Volume 14:1529-1540. doi:10.2147/CCID.S284796

35. Armstrong ML, DeBoer S, Cetta F. Infective Endocarditis After Body Art: A Review of the Literature and Concerns. Journal of Adolescent Health. 2008;43(3):217-225. doi:10.1016/j.jadohealth.2008.02.008

36. Ramey K, Ibrahim J, Brodell RT. Verruca localization predominately in black tattoo ink: a retrospective case series. Acad Dermatol Venereol. 2016;30(10). doi:10.1111/jdv.13283

37. Kirchhof MG, Wong SM. Tattoos and human papilloma virus: A case report of tattoo-associated flat warts (verrucae planae). SAGE Open Medical Case Reports. 2019;7:2050313X19857416. doi:10.1177/2050313X19857416

38. Ruocco V, Brunetti G, Puca R, Ruocco E. The immunocompromised district: a unifying concept for lymphoedematous, herpes‐infected and otherwise damaged sites. Acad Dermatol Venereol. 2009;23(12):1364-1373. doi:10.1111/j.1468-3083.2009.03345.x

39. Begolli Gerqari A, Ferizi M, Kotori M, et al. Activation of Herpes Simplex Infection after Tattoo. Acta Dermatovenerol Croat. 2018;26(1):75-76.

40. Anderson LL, Cardone JS, McCOLLOUGH ML, Grabski WJ. Tattoo Pigment Mimicking Metastatic Malignant Melanoma: Dermatologic Surgery. 1996;22(1):92-94. doi:10.1111/j.1524-4725.1996.tb00578.x

41. Sepehri M, Sejersen T, Qvortrup K, Lerche CM, Serup J. Tattoo Pigments Are Observed in the Kupffer Cells of the Liver Indicating Blood-Borne Distribution of Tattoo Ink. Dermatology. 2017;233(1):86-93. doi:10.1159/000468149

42. Nielsen C, Jerkeman M, Jöud AS. Tattoos as a risk factor for malignant lymphoma: a population-based case–control study. eClinicalMedicine. 2024;72:102649. doi:10.1016/j.eclinm.2024.102649

43. McConnell T, Xu J, Freeman J, Zak I, Frain J. Investigating the potential association between tattoos and lymphoma: an exploratory systematic review and meta-analysis. eClinicalMedicine. 2025;89:103563. doi:10.1016/j.eclinm.2025.103563

44. Clemmensen SB, Mengel-From J, Kaprio J, Frederiksen H, Von Bornemann Hjelmborg J. Tattoo ink exposure is associated with lymphoma and skin cancers – a Danish study of twins. BMC Public Health. 2025;25(1):170. doi:10.1186/s12889-025-21413-3

45. McCarty RD, Trabert B, Kriebel D, et al. Tattoos and Risk of Hematologic Cancer: A Population‐Based Case–Control Study in Utah. Cancer Medicine. 2024;13(20):e70260. doi:10.1002/cam4.70260

46. Kluger N, Koljonen V. Tattoos, inks, and cancer. The Lancet Oncology. 2012;13(4):e161-e168. doi:10.1016/S1470-2045(11)70340-0

47. Brusasco M, Spagnolini S, Mazzoni L, Magi S, Scarcella G, Stanganelli I. Melanoma Arising in Tattoos: A Case Series and Scoping Review of the Literature. Cancers. 2025;17(5):767. doi:10.3390/cancers17050767

48. Benandi K, Sieving D, Martin K, Wolf K. Malignant melanoma arising within tattoos as a risk factor for delayed diagnosis: a case report and systematic review. DOJ. 2025;31(3). doi:10.5070/D331365358

Journal of Education, Health and Sport

Downloads

  • PDF

Published

2026-09-24

How to Cite

1.
NIERYCHLEWSKA, Alicja, FALIS, Michał, SOLECKA, Alicja, BRONISŁAWSKA, Agata, BRONISŁAWSKI, Robert, STENCELEWSKI, Damian, SIKORSKA, Laura Magdalena, BONIECKA, Magdalena Aleksandra and GRUDZIŃSKA, Michalina. The Tattoos and the risk of health complications: a narrative review: Narrative review. Journal of Education, Health and Sport. Online. 24 September 2026. Vol. 95, p. 73995. [Accessed 25 September 2026]. DOI 10.12775/JEHS.2026.95.73995.
  • ISO 690
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

Issue

Vol. 95 (2026)

Section

Medical Sciences

License

Copyright (c) 2026 Alicja Nierychlewska, Michał Falis, Alicja Solecka, Agata Bronisławska, Robert Bronisławski, Damian Stencelewski, Laura Magdalena Sikorska, Magdalena Aleksandra Boniecka, Michalina Grudzińska

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

Stats

Number of views and downloads: 22
Number of citations: 0

Search

Search

Browse

  • Issue archive

User

User

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians

Newsletter

Subscribe Unsubscribe

Tags

Search using one of provided tags:

tattoo, health complications, tattoo ink, allergic reactions, pigment migration
Up

Akademicka Platforma Czasopism

Najlepsze czasopisma naukowe i akademickie w jednym miejscu

apcz.umk.pl

Partners

  • Akademia Ignatianum w Krakowie
  • Akademickie Towarzystwo Andragogiczne
  • Fundacja Copernicus na rzecz Rozwoju Badań Naukowych
  • Instytut Historii im. Tadeusza Manteuffla Polskiej Akademii Nauk
  • Instytut Kultur Śródziemnomorskich i Orientalnych PAN
  • Instytut Tomistyczny
  • Karmelitański Instytut Duchowości w Krakowie
  • Ministerstwo Kultury i Dziedzictwa Narodowego
  • Państwowa Akademia Nauk Stosowanych w Krośnie
  • Państwowa Akademia Nauk Stosowanych we Włocławku
  • Państwowa Wyższa Szkoła Zawodowa im. Stanisława Pigonia w Krośnie
  • Polska Fundacja Przemysłu Kosmicznego
  • Polskie Towarzystwo Ekonomiczne
  • Polskie Towarzystwo Ludoznawcze
  • Towarzystwo Miłośników Torunia
  • Towarzystwo Naukowe w Toruniu
  • Uniwersytet im. Adama Mickiewicza w Poznaniu
  • Uniwersytet Komisji Edukacji Narodowej w Krakowie
  • Uniwersytet Mikołaja Kopernika
  • Uniwersytet w Białymstoku
  • Uniwersytet Warszawski
  • Wojewódzka Biblioteka Publiczna - Książnica Kopernikańska
  • Wyższe Seminarium Duchowne w Pelplinie / Wydawnictwo Diecezjalne „Bernardinum" w Pelplinie

© 2021- Nicolaus Copernicus University Accessibility statement Shop