The Effects of Yoga on Physical Activity and Respiratory Health in Duchenne Muscular Dystrophy: A Literature Review
DOI:
https://doi.org/10.12775/JEHS.2026.91.70723Keywords
Duchenne muscular dystrophy, yoga, respiratory function, Physical activity, rehabilitationAbstract
Purpose: Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder characterized by declining motor performance and respiratory function. The aim of this study was to evaluate current scientific evidence on the effects of yoga-based interventions on physical activity and pulmonary function in individuals with DMD.
Materials and Methods: A narrative literature review was conducted using PubMed and Google Scholar databases. The search included studies published between 2000 and 2026 focusing on Duchenne muscular dystrophy, rehabilitation, respiratory function, physical activity, and yoga-based interventions. Articles were screened according to their relevance to yoga-based rehabilitation approaches in patients with DMD.
Results: The reviewed studies indicate that yoga interventions may improve functional capacity, balance, and tolerance for daily activities in children with DMD. Programs combining adapted postural exercises (asanas), breathing techniques (pranayama), and relaxation practices were associated with improved pulmonary function parameters and autonomic regulation, including increased heart rate variability. Yoga programs were generally safe and well tolerated.
Conclusions: Yoga may be a supportive component of multidisciplinary rehabilitation in DMD. It may contribute to improved respiratory function, functional performance, and overall well-being. Further large-scale studies with standardized protocols are needed to confirm long-term clinical benefits.
References
1. Hoffman EP, Brown RH Jr, Kunkel LM. Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell. 1987 Dec 24;51(6):919-28.
https://doi.org/10.1016/0092-8674(87)90579-4
2. Emery AE. The muscular dystrophies. Lancet. 2002 Feb 23;359(9307):687-95. https://doi.org/10.1016/s0140-6736(02)07815-7
3. Bushby K, Finkel R, Birnkrant DJ, Case LE, Clemens PR, Cripe L, Kaul A, Kinnett K, McDonald C, Pandya S, Poysky J, Shapiro F, Tomezsko J, Constantin C; DMD Care Considerations Working Group. Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management. Lancet Neurol. 2010 Jan;9(1):77-93.
https://doi.org/10.1016/s1474-4422(09)70271-6
4. Pane M, Mazzone ES, Sivo S, Sormani MP, Messina S, D'Amico A, Carlesi A, Vita G, Fanelli L, Berardinelli A, Torrente Y, Lanzillotta V, Viggiano E, D Ambrosio P, Cavallaro F, Frosini S, Barp A, Bonfiglio S, Scalise R, De Sanctis R, Rolle E, Graziano A, Magri F, Palermo C, Rossi F, Donati MA, Sacchini M, Arnoldi MT, Baranello G, Mongini T, Pini A, Battini R, Pegoraro E, Previtali S, Bruno C, Politano L, Comi GP, Bertini E, Mercuri E. Long term natural history data in ambulant boys with Duchenne muscular dystrophy: 36-month changes. PLoS One. 2014 Oct 1;9(10):e108205.
https://doi.org/10.1371/journal.pone.0108205
5. McDonald CM, Henricson EK, Abresch RT, Florence J, Eagle M, Gappmaier E, Glanzman AM; PTC124-GD-007-DMD Study Group; Spiegel R, Barth J, Elfring G, Reha A, Peltz SW. The 6-minute walk test and other clinical endpoints in duchenne muscular dystrophy: reliability, concurrent validity, and minimal clinically important differences from a multicenter study. Muscle Nerve. 2013 Sep;48(3):357-68. https://doi.org/10.1002/mus.23905
6. Voet NB, van der Kooi EL, van Engelen BG, Geurts AC. Strength training and aerobic exercise training for muscle disease. Cochrane Database Syst Rev. 2019 Dec 6;12(12):CD003907.
doi:10.1002/14651858.CD003907.pub5
7. Güneş Gencer GY, Yilmaz Ö. The effect of trunk training on trunk control, upper extremity, and pulmonary function in children with Duchenne muscular dystrophy: A randomized clinical trial. Clin Rehabil. 2022 Mar;36(3):369-378.
doi:10.3233/BMR-181390
8. Topin N, Matecki S, Le Bris S, Rivier F, Echenne B, Prefaut C, Ramonatxo M. Dose-dependent effect of individualized respiratory muscle training in children with Duchenne muscular dystrophy. Neuromuscul Disord. 2002 Aug;12(6):576-83. https://doi.org/10.1016/S0960-8966(02)00005-6
9. Mayer OH, Finkel RS, Rummey C, Benton MJ, Glanzman AM, Flickinger J, Lindström BM, Meier T. Characterization of pulmonary function in Duchenne Muscular Dystrophy. Pediatr Pulmonol. 2015 May;50(5):487-94.
https://doi.org/10.1002/ppul.23172
10. Silva IS, Pedrosa R, Azevedo IG, Forbes AM, Fregonezi GA, Dourado Junior ME, Lima SR, Ferreira GM. Respiratory muscle training in children and adults with neuromuscular disease. Cochrane Database Syst Rev. 2019 Sep 5;9(9):CD011711. https://doi.org/10.1002/14651858.CD011711.pub2
11. Mahdy MAA. Skeletal muscle fibrosis: an overview. Cell Tissue Res. 2019 Mar;375(3):575-588.
https://doi.org/10.1007/s00441-018-2955-2
12. Birnkrant DJ, Bushby K, Bann CM, Alman BA, Apkon SD, Blackwell A, Case LE, Cripe L, Hadjiyannakis S, Olson AK, Sheehan DW, Bolen J, Weber DR, Ward LM; DMD Care Considerations Working Group. Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management. Lancet Neurol. 2018 Apr;17(4):347-361.
https://doi.org/10.1016/s1474-4422(18)30025-5
13. Finder JD, Birnkrant D, Carl J, Farber HJ, Gozal D, Iannaccone ST, Kovesi T, Kravitz RM, Panitch H, Schramm C, Schroth M, Sharma G, Sievers L, Silvestri JM, Sterni L; American Thoracic Society. Respiratory care of the patient with Duchenne muscular dystrophy: ATS consensus statement. Am J Respir Crit Care Med. 2004 Aug 15;170(4):456-65.
https://doi.org/10.1164/rccm.200307-885st
14. Eagle M. Report on the muscular dystrophy campaign workshop: exercise in neuromuscular diseases Newcastle, January 2002. Neuromuscul Disord. 2002 Dec;12(10):975-83.
https://doi.org/10.1016/s0960-8966(02)00136-0
15. Finder JD. A 2009 perspective on the 2004 American Thoracic Society statement, "respiratory care of the patient with Duchenne muscular dystrophy". Pediatrics. 2009 May;123 Suppl 4:S239-41.
https://doi.org/10.1542/peds.2008-2952i
16. LoMauro A, Romei M, Gandossini S, Pascuzzo R, Vantini S, D'Angelo MG, Aliverti A. Evolution of respiratory function in Duchenne muscular dystrophy from childhood to adulthood. Eur Respir J. 2018 Feb 7;51(2):1701418. https://doi.org/10.1183/13993003.01418-2017
17. Yotsukura M, Sasaki K, Kachi E, Sasaki A, Ishihara T, Ishikawa K. Circadian rhythm and variability of heart rate in Duchenne-type progressive muscular dystrophy. Am J Cardiol. 1995 Nov 1;76(12):947-51.
https://doi.org/10.1016/s0002-9149(99)80267-7
18. MICHALSKA, Anna Teresa, ŚWIDA, Michał, KUBUJ, Cezary, ADAŚKO, Grzegorz, MAZUR, Urszula, BAZAREWICZ, Jakub, SIWIK, Marcin, DMOWSKI, Daniel, OGONOWSKA, Paulina and WASZAK, Julia. Duchenne muscular dystrophy - disease characterization and emergent genetic therapy - literature review. Quality in Sport. Online. 10 July 2025. Vol. 43, p. 62338.
https://doi.org/10.12775/QS.2025.43.62338
19. Saud A, Abbasi M, Merris H, Parth P, Jones XM, Aggarwal R, Gupta L. Harnessing the benefits of yoga for myositis, muscle dystrophies, and other musculoskeletal disorders. Clin Rheumatol. 2022 Nov;41(11):3285-3297. https://doi.org/10.1007/s10067-022-06280-2
20. Woodyard C. Exploring the therapeutic effects of yoga and its ability to increase quality of life. Int J Yoga. 2011 Jul;4(2):49-54.
https://doi.org/10.4103/0973-6131.85485
21. Ross A, Thomas S. The health benefits of yoga and exercise: a review of comparison studies. J Altern Complement Med. 2010 Jan;16(1):3-12. https://doi.org/10.1089/acm.2009.0044
22. Field T. Yoga clinical research review. Complement Ther Clin Pract. 2011 Feb;17(1):1-8.
https://doi.org/10.1016/j.ctcp.2010.09.007
23. Brown RP, Gerbarg PL. Sudarshan Kriya Yogic breathing in the treatment of stress, anxiety, and depression. Part II--clinical applications and guidelines. J Altern Complement Med. 2005 Aug;11(4):711-7.
https://doi.org/10.1089/acm.2005.11.711
24. Tyagi A, Cohen M. Yoga and heart rate variability: a comprehensive review of the literature. Int J Yoga. 2016;9(2):97-113.
https://doi.org/10.4103/0973-6131.183712
25. Sengupta P. Health Impacts of Yoga and Pranayama: A State-of-the-Art Review. Int J Prev Med. 2012 Jul;3(7):444-58. PMID: 22891145; PMCID: PMC3415184.
26. Rodrigues MR, Carvalho CR, Santaella DF, Lorenzi-Filho G, Marie SK. Effects of yoga breathing exercises on pulmonary function in patients with Duchenne muscular dystrophy: an exploratory analysis. J Bras Pneumol. 2014 Mar-Apr;40(2):128-33. https://doi.org/10.1590/s1806-37132014000200005
27. Dhargave P, Nalini A, Nagarathna R, Sendhilkumar R, James TT, Raju TR, Sathyaprabha TN. Effect of Yoga and Physiotherapy on Pulmonary Functions in Children with Duchenne Muscular Dystrophy - A Comparative Study. Int J Yoga. 2021 May-Aug;14(2):133-140.
https://doi.org/10.4103/ijoy.ijoy_49_20
28. Pradnya D, Nalini A, Nagarathna R, Raju TR, Sendhilkumar R, Meghana A, Sathyaprabha TN. Effect of Yoga as an Add-on Therapy in the Modulation of Heart Rate Variability in Children with Duchenne Muscular Dystrophy. Int J Yoga. 2019 Jan-Apr;12(1):55-61.
https://doi.org/10.4103/ijoy.IJOY_12_18
29. Puja MS, Jyothy KB, Kulkarni V, Srihari S. Potential benefits of Ayurveda in Duchenne muscular Dystrophy: A case based analysis. J Ayurveda Integr Med. 2026 Jan-Feb;17(1):101272.
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Copyright (c) 2026 Karolina Frączek, Agnieszka Janaszek, Aleksandra Strzępek, Kinga Kałuża, Agnieszka Chmurska, Aleksandra Majchrzyk, Julia Łyżwa, Michał Pater, Natalia Kałwa, Mateusz Smerdzyński
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