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Journal of Education, Health and Sport

Health Complications Associated with Anabolic-Androgenic Steroid Use in Physically Active Men: A Literature Review
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  • Health Complications Associated with Anabolic-Androgenic Steroid Use in Physically Active Men: A Literature Review
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  4. Medical Sciences

Health Complications Associated with Anabolic-Androgenic Steroid Use in Physically Active Men: A Literature Review

Authors

  • Urszula Kacprzak Clinical Hospital of Poznań University of Medical Sciences, Poznan, Poland https://orcid.org/0009-0008-2380-3187
  • Zofia Biernacka Clinical Hospital of Poznań University of Medical Sciences, Poznan, Poland https://orcid.org/0009-0004-3924-1757
  • Mikołaj Celmer Clinical Hospital of Poznań University of Medical Sciences, Poznan, Poland https://orcid.org/0009-0008-2379-8787
  • Julia Kossakowska Karol Marcinkowski University Hospital in Zielona Gora, Zielona Gora, Poland https://orcid.org/0009-0003-2682-4796
  • Mateusz Majchrzak Clinical Hospital of Poznań University of Medical Sciences, Poznan, Poland https://orcid.org/0009-0008-4775-7525
  • Marcin Ruszkowski Karol Marcinkowski University Hospital in Zielona Gora, Zielona Gora, Poland https://orcid.org/0009-0007-2699-8496

DOI:

https://doi.org/10.12775/JEHS.2026.90.70582

Keywords

anabolic-androgenic steroids, adverse effects, cardiovascular complications, Endocrine disorder, hormonal doping

Abstract

Aim. The aim of this study was to review the current scientific literature on the adverse effects of anabolic-androgenic steroids (AAS) use in physically active men and to highlight the need for further research in this field.

Introduction. The use of anabolic-androgenic steroids among physically active individuals is an increasing public health concern and is associated with significant health risks. In recent years, the use of these substances has expanded beyond professional athletes to include recreationally active individuals.

Methods. A literature review was conducted using the PubMed and Google Scholar databases. The search included studies published between 2017 and 2025 focusing on the health effects of AAS use in physically active men.

Results. Analysis of the available literature indicates that supraphysiological doses of AAS are associated with numerous adverse effects. The most significant complications involve the cardiovascular system (including hypertension and atherosclerosis), the endocrine system (particularly suppression of endogenous testosterone production and infertility), and psychiatric health (including mood disorders and increased aggression). Additional complications affecting the liver, kidneys, and skin have also been reported.

Discussion. The findings suggest that AAS use poses a serious health risk, particularly due to its multi-system effects and the potential for long-term complications. The increasing prevalence of AAS use among recreational athletes further emphasizes the need for greater clinical awareness and early identification of affected individuals.

Conclusion. Increasing awareness of the health risks associated with AAS use among both patients and healthcare professionals is essential for effective prevention and management. Further research is needed to better understand the long-term consequences of AAS use.

References

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3. Bond P, Smit DL, de Ronde W. Anabolic–androgenic steroids: How do they work and what are the risks? Front Endocrinol (Lausanne). 2022;13:1059473. https://doi.org/10.3389/fendo.2022.1059473

4. Borowiec A, et al. Impact of anabolic–androgenic steroid abuse on the cardiovascular system: Molecular mechanisms and clinical implications. Int J Mol Sci. 2025;26(22):11037. https://doi.org/10.3390/ijms262211037

5. Smit DL, et al. Disruption and recovery of testicular function during and after androgen abuse: The HAARLEM study. Hum Reprod. 2021;36(4):880–890. https://doi.org/10.1093/humrep/deaa366

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7. Baggish AL, et al. Cardiovascular toxicity of illicit anabolic-androgenic steroid use. Circulation.2017;135(21):1991–2002. https://doi.org/10.1161/CIRCULATIONAHA.116.026945

8. Torrisi M, et al. Sudden cardiac death in anabolic-androgenic steroid users: A literature review.Medicina(Kaunas).2020;56(11):587. https://doi.org/10.3390/medicina56110587

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Journal of Education, Health and Sport

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Published

2026-04-22

How to Cite

1.
KACPRZAK, Urszula, BIERNACKA, Zofia, CELMER, Mikołaj, KOSSAKOWSKA, Julia, MAJCHRZAK, Mateusz and RUSZKOWSKI, Marcin. Health Complications Associated with Anabolic-Androgenic Steroid Use in Physically Active Men: A Literature Review. Journal of Education, Health and Sport. Online. 22 April 2026. Vol. 90, p. 70582. [Accessed 22 April 2026]. DOI 10.12775/JEHS.2026.90.70582.
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Vol. 90 (2026)

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Medical Sciences

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Copyright (c) 2026 Urszula Kacprzak, Zofia Biernacka, Mikołaj Celmer, Julia Kossakowska, Mateusz Majchrzak, Marcin Ruszkowski

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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