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Journal of Education, Health and Sport

The role of procedures used in the treatment of androgenetic alopecia - a literature review
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The role of procedures used in the treatment of androgenetic alopecia - a literature review

Authors

  • Jagienka Perzyńska Norbert Barlicki Memorial Teaching Hospital No. 1 of the Medical University of Lodz https://orcid.org/0009-0006-3723-7708
  • Weronika Bagińska Norbert Barlicki Memorial Teaching Hospital No. 1 of the Medical University of Lodz https://orcid.org/0009-0002-6325-0915
  • Urszula Załuska Masovian Specialist Hospital in Radom https://orcid.org/0009-0008-4666-8790
  • Kinga Krzyżowska Norbert Barlicki Memorial Teaching Hospital No. 1 of the Medical University of Lodz https://orcid.org/0009-0004-7385-9497
  • Jaśmina Podkościelna Marszałek Józef Piłsudski Independent Public Healthcare Facility in Płońsk https://orcid.org/0009-0004-6102-6762
  • Kamila Ryszkowska Norbert Barlicki Memorial Teaching Hospital No. 1 of the Medical University of Lodz https://orcid.org/0009-0000-1458-0657
  • Natalia Pawelec National Medical Institute of the Ministry of the Interior and Administration https://orcid.org/0009-0003-1234-8450

DOI:

https://doi.org/10.12775/JEHS.2026.90.70145

Keywords

androgenetic alopecia, platelet rich plasma, hair transplantation, hair loss, AGA treatment, microneedling

Abstract

The aim of the thesis is a review and critical analysis of invasive methods for treating androgenetic alopecia (AGA), including platelet- rich plasma therapy (PRP), low-level laser therapy (LLLT), microneedling (MN), hair transplantation and mesotherapy. The paper analyzed the results of randomized clinical trials, observational studies, and meta-analyses published over the past twelve years, with particular emphasis on safety indicators and the durability of effects. The results of available studies indicate that invasive treatment methods can lead to a significant improvement in hair density and quality, especially when an appropriate selected combination therapy is used. However, the effectiveness of individual technique varies, and their application requires appropriate patient qualification and consideration of the risk of complications. In conclusion, invasive methods for the treatment of androgenetic alopecia represent a promising therapeutic approach; nevertheless, further high-quality clinical studies are necessary to optimize treatment protocols and evaluate long-term outcomes. 

References

1. Qiu, Yueqi, et al. Systematic Review and Meta-Analysis of the Association between Metabolic Syndrome and Androgenetic Alopecia. Acta Dermato-Venereologica, vol. 102, 8 Feb. 2022, p. adv00645, https://doi.org/10.2340/actadv.v101.1012.

2. Pawlik, Wiktoria, et al. Hair Loss Therapies: A Review and Comparison of Traditional and Modern Treatment Methods. Journal of Education Health and Sport, vol. 75, 25 Nov. 2024, p. 56191, www.researchgate.net/publication/386161456_Hair_loss_therapies_a_review_and_comparison_of_traditional_and_modern_treatment_methods, https://doi.org/10.12775/JEHS.2024.75.56191.

3. Aukerman, Erica L., and Mohammad Jafferany. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review. Journal of Cosmetic Dermatology, vol. 22, no. 1, 25 Apr. 2022, https://doi.org/10.1111/jocd.14983.

4. Piraccini, B. M., and A. Alessandrini. Androgenetic Alopecia. Giornale Italiano Di Dermatologia E Venereologia: Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia, vol. 149, no. 1, 1 Feb. 2014, pp. 15–24, pubmed.ncbi.nlm.nih.gov/24566563/.

5. Müller Ramos, Paulo, et al. Female Pattern Hair Loss: Therapeutic Update. Anais Brasileiros de Dermatologia, vol. 98, no. 4, Mar. 2023, https://doi.org/10.1016/j.abd.2022.09.006.

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10. View of Non-Pharmacological Therapies in the Treatment of Chemotherapy-Induced Alopecia – a Literature Review. Apcz.umk.pl, 2026, apcz.umk.pl/JEHS/article/view/56966/41068. Accessed 20 Mar. 2026.

11. STL Volume 24 Number 5. Platelet-Rich Plasma (PRP): Current Applications in Dermatology. Skin Therapy Letter. Published October 2019. Accessed March 18, 2026. https://www.skintherapyletter.com/acne/platelet-rich-plasma-prp/

12. Pillai J, Mysore V. Role of low-level light therapy (LLLT) in androgenetic alopecia. Journal of Cutaneous and Aesthetic Surgery. 2021;14(4):385. doi:https://doi.org/10.4103/jcas.jcas_218_20.

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14. Ahmed KMA, Kozaa YA, Abuawwad MT, et al. Evaluating the efficacy and safety of combined microneedling therapy versus topical Minoxidil in androgenetic alopecia: a systematic review and meta-analysis. Archives of Dermatological Research. 2025;317(1). doi:https://doi.org/10.1007/s00403-025-04032-1.

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17. Reguero del Cura L, De Quintana Sancho A, Rubio Lombraña M, López Sundh AE, González López MA. Two Cases of Paradoxical Nonscarring Alopecia after Mesotherapy with Dutasteride. Skin Appendage Disorders. Published online August 18, 2021:1-3. doi:https://doi.org/10.1159/000518043.

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Journal of Education, Health and Sport

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Published

2026-04-10

How to Cite

1.
PERZYŃSKA, Jagienka, BAGIŃSKA, Weronika, ZAŁUSKA, Urszula, KRZYŻOWSKA, Kinga, PODKOŚCIELNA, Jaśmina, RYSZKOWSKA, Kamila and PAWELEC, Natalia. The role of procedures used in the treatment of androgenetic alopecia - a literature review. Journal of Education, Health and Sport. Online. 10 April 2026. Vol. 90, p. 70145. [Accessed 11 April 2026]. DOI 10.12775/JEHS.2026.90.70145.
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Vol. 90 (2026)

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Medical Sciences

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Copyright (c) 2026 Jagienka Perzyńska, Weronika Bagińska, Urszula Załuska, Kinga Krzyżowska, Jaśmina Podkościelna, Kamila Ryszkowska, Natalia Pawelec

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