Breastfeeding and postpartum depression mechanisms and care
DOI:
https://doi.org/10.12775/JEHS.2026.88.68043Keywords
Breastfeeding, postpartum depressionAbstract
Objective: To synthesize evidence on the association between breastfeeding and postpartum depression, emphasizing bidirectionality, proposed mechanisms, key modifiers (self-efficacy, stress and social support), and integrated intervention strategies.
Methods: Narrative review of the peer-reviewed literature provided by the author, prioritizing meta-analyses, systematic reviews, randomized trials, and large observational or qualitative studies.
Results: Across settings, postpartum depressive symptoms are associated with reduced breastfeeding initiation, exclusivity, and duration. Early cessation and negative breastfeeding experiences are also associated with higher depressive symptom burden in some populations. Self-efficacy and social support consistently correlate with both mood and feeding outcomes, and stress appears to amplify risk. Interventions spanning pregnancy through the postpartum period and combining lactation support with psychosocial care show the most consistent promise.
Conclusions: Because breastfeeding and postpartum depression influence one another and share modifiable determinants, clinical pathways should integrate screening, individualized feeding support, and stepped mental health care.
References
1. Henshaw EJ. Breastfeeding and Postpartum Depression: A Review of Relationships and Potential Mechanisms. Curr Psychiatry Rep. 2023 Dec;25(12):803-808. doi: 10.1007/s11920-023-01471-3. Epub 2023 Oct 31. PMID: 37906349. DOI: 10.1007/s11920-023-01471-3
2. Xia M, Luo J, Wang J, Liang Y. Association between breastfeeding and postpartum depression: A meta-analysis. J Affect Disord. 2022 Jul 1;308:512-519. doi: 10.1016/j.jad.2022.04.091. Epub 2022 Apr 20. PMID: 35460745. DOI: 10.1016/j.jad.2022.04.091
3. Ahmadinezhad GS, Karimi FZ, Abdollahi M, NaviPour E. Association between postpartum depression and breastfeeding self-efficacy in mothers: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2024 Apr 12;24(1):273. doi: 10.1186/s12884-024-06465-4. Erratum in: BMC Pregnancy Childbirth. 2024 May 17;24(1):377. doi: 10.1186/s12884-024-06576-y. PMID: 38609849; PMCID: PMC11015580. DOI: 10.1186/s12884-024-06465-4
4. Mercan Y, Tari Selcuk K. Association between postpartum depression level, social support level and breastfeeding attitude and breastfeeding self-efficacy in early postpartum women. PLoS One. 2021 Apr 2;16(4):e0249538. doi: 10.1371/journal.pone.0249538. PMID: 33798229; PMCID: PMC8018654. DOI: 10.1371/journal.pone.0249538
5. Dennis CL, Singla DR, Brown HK, Savel K, Clark CT, Grigoriadis S, Vigod SN. Postpartum Depression: A Clinical Review of Impact and Current Treatment Solutions. Drugs. 2024 Jun;84(6):645-659. doi: 10.1007/s40265-024-02038-z. Epub 2024 May 30. PMID: 38811474. DOI: 10.1007/s40265-024-02038-z
6. Dessì A, Pianese G, Mureddu P, Fanos V, Bosco A. From Breastfeeding to Support in Mothers' Feeding Choices: A Key Role in the Prevention of Postpartum Depression? Nutrients. 2024 Jul 16;16(14):2285. doi: 10.3390/nu16142285. PMID: 39064728; PMCID: PMC11279849. DOI: 10.3390/nu16142285
7. Rodríguez-Gallego I, Vila-Candel R, Corrales-Gutierrez I, Gomez-Baya D, Leon-Larios F. Evaluation of the Impact of a Midwife-Led Breastfeeding Group Intervention on Prevention of Postpartum Depression: A Multicentre Randomised Clinical Trial. Nutrients. 2024 Jan 10;16(2):227. doi: 10.3390/nu16020227. PMID: 38257120; PMCID: PMC10821517. DOI: 10.3390/nu16020227
8. Van der Zee-van den Berg AI, Boere-Boonekamp MM, Groothuis-Oudshoorn CGM, Reijneveld SA. Postpartum depression and anxiety: a community-based study on risk factors before, during and after pregnancy. J Affect Disord. 2021 May 1;286:158-165. doi: 10.1016/j.jad.2021.02.062. Epub 2021 Mar 4. PMID: 33725615. DOI: 10.1016/j.jad.2021.02.062
9. Masi AC, Stewart CJ. Role of breastfeeding in disease prevention. Microb Biotechnol. 2024 Jul;17(7):e14520. doi: 10.1111/1751-7915.14520. PMID: 38946112; PMCID: PMC11214977. DOI: 10.1111/1751-7915.14520
10. Treatment and Management of Mental Health Conditions During Pregnancy and Postpartum: ACOG Clinical Practice Guideline No. 5. Obstet Gynecol. 2023 Jun 1;141(6):1262-1288. doi: 10.1097/AOG.0000000000005202. PMID: 37486661. DOI: 10.1097/AOG.0000000000005202
11. Rupanagunta GP, Nandave M, Rawat D, Upadhyay J, Rashid S, Ansari MN. Postpartum depression: aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management. Saudi Pharm J. 2023 Jul;31(7):1274-1293. doi: 10.1016/j.jsps.2023.05.008. Epub 2023 May 15. PMID: 37304359; PMCID: PMC10250836. DOI: 10.1016/j.jsps.2023.05.008
12. Kim S, Park M, Ahn S. The Impact of Antepartum Depression and Postpartum Depression on Exclusive Breastfeeding: A Systematic Review and Meta-Analysis. Clin Nurs Res. 2022 Jun;31(5):866-880. doi: 10.1177/10547738211053507. Epub 2021 Oct 31. PMID: 34719979. DOI: 10.1177/10547738211053507
13. Eleftheriou G, Zandonella Callegher R, Butera R, De Santis M, Cavaliere AF, Vecchio S, Lanzi C, Davanzo R, Mangili G, Bondi E, Somaini L, Gallo M, Balestrieri M, Mannaioni G, Salvatori G, Albert U. Consensus Panel Recommendations for the Pharmacological Management of Breastfeeding Women with Postpartum Depression. Int J Environ Res Public Health. 2024 Apr 26;21(5):551. doi: 10.3390/ijerph21050551. PMID: 38791766; PMCID: PMC11121006. DOI: 10.3390/ijerph21050551
14. Toledo C, Cianelli R, Villegas Rodriguez N, De Oliveira G, Gattamorta K, Wojnar D, Ojukwu E. The significance of breastfeeding practices on postpartum depression risk. Public Health Nurs. 2022 Jan;39(1):15-23. doi: 10.1111/phn.12969. Epub 2021 Sep 12. PMID: 34510526. DOI: 10.1111/phn.12969
15. Lubis PN, Saputra M, Rabbani MW. A systematic review of the benefits of breastfeeding against postpartum depression in low-middle-income countries. J Ment Health. 2025 Jun;34(3):305-317. doi: 10.1080/09638237.2024.2361232. Epub 2024 Jun 13. PMID: 38869015. DOI: 10.1080/09638237.2024.2361232
16. Onat G, Karakoç H. Three spirals: Breastfeeding problems, growth spurts, and postpartum depression. Perspect Psychiatr Care. 2021 Apr;57(2):770-776. doi: 10.1111/ppc.12612. Epub 2020 Aug 27. PMID: 32853416. DOI: 10.1111/ppc.12612
17. Yahya NFS, Teng NIMF, Shafiee N, Juliana N. Association between Breastfeeding Attitudes and Postpartum Depression among Mothers with Premature Infants during COVID-19 Pandemic. Int J Environ Res Public Health. 2021 Oct 17;18(20):10915. doi: 10.3390/ijerph182010915. PMID: 34682652; PMCID: PMC8535779. DOI: 10.3390/ijerph182010915
18. Baeisa RS, Aldardeir NF, Alsulami MT, Alsulami AH, Al-Sharif JH, Alshahrany TA, Alghamdi WA. Breastfeeding Self-efficacy is Inversely Associated with Postpartum Depression: Findings from a Tertiary Hospital in Saudi Arabia. Saudi J Med Med Sci. 2023 Oct-Dec;11(4):292-298. doi: 10.4103/sjmms.sjmms_601_22. Epub 2023 Oct 6. PMID: 37970459; PMCID: PMC10634464. DOI: 10.4103/sjmms.sjmms_601_22
19. Figueiredo B, Pinto TM, Costa R. Exclusive Breastfeeding Moderates the Association Between Prenatal and Postpartum Depression. J Hum Lact. 2021 Nov;37(4):784-794. doi: 10.1177/0890334421991051. Epub 2021 Feb 11. PMID: 33571030. DOI: 10.1177/0890334421991051
20. Bruce KE, Wouk K, Grewen KM, Pearson B, Meltzer-Brody S, Stuebe AM, Bauer AE. HPA axis dysregulation and postpartum depression and anxiety symptoms in breastfeeding vs bottle-feeding parents. Psychoneuroendocrinology. 2025 Feb;172:107253. doi: 10.1016/j.psyneuen.2024.107253. Epub 2024 Nov 27. PMID: 39675161; PMCID: PMC11830542. DOI: 10.1016/j.psyneuen.2024.107253
21. Neupane S, Vuong AM, Haboush-Deloye A, Mancha K, Buccini G. Association between postpartum anxiety and depression and exclusive and continued breastfeeding practices: a cross-sectional study in Nevada, USA. Int Breastfeed J. 2025 May 19;20(1):39. doi: 10.1186/s13006-025-00734-4. PMID: 40390039; PMCID: PMC12090565. DOI: 10.1186/s13006-025-00734-4
22. Pezley L, Cares K, Duffecy J, Koenig MD, Maki P, Odoms-Young A, Clark Withington MH, Lima Oliveira M, Loiacono B, Prough J, Tussing-Humphreys L, Buscemi J. Efficacy of behavioral interventions to improve maternal mental health and breastfeeding outcomes: a systematic review. Int Breastfeed J. 2022 Sep 5;17(1):67. doi: 10.1186/s13006-022-00501-9. PMID: 36064573; PMCID: PMC9446548. DOI: 10.1186/s13006-022-00501-9
23. Öztekin-Ateş N, Arguvanli-Çoban S, Dinçer Y. The Relationship of Postpartum Depression With Breastfeeding Self-Efficacy and Perceived Social Support in the Postpartum Period: A Sample From an Obstetrics-Gynaecology and Paediatrics Hospital. Scand J Caring Sci. 2025 Sep;39(3):e70050. doi: 10.1111/scs.70050. PMID: 40605407. DOI: 10.1111/scs.70050
24. Sanni SO, Adeoye IA, Bella-Awusah TT, Bello OO. Influence of postpartum depression on maternal-infant bonding and breastfeeding practices among mothers in Abeokuta, Ogun state. Discov Ment Health. 2024 Oct 25;4(1):46. doi: 10.1007/s44192-024-00104-2. PMID: 39453530; PMCID: PMC11511802. DOI: 10.1007/s44192-024-00104-2
25. Gavine A, Shinwell SC, Buchanan P, Farre A, Wade A, Lynn F, Marshall J, Cumming SE, Dare S, McFadden A. Support for healthy breastfeeding mothers with healthy term babies. Cochrane Database Syst Rev. 2022 Oct 25;10(10):CD001141. doi: 10.1002/14651858.CD001141.pub6. PMID: 36282618; PMCID: PMC9595242. DOI: 10.1002/14651858.CD001141.pub6
26. Modak A, Ronghe V, Gomase KP. The Psychological Benefits of Breastfeeding: Fostering Maternal Well-Being and Child Development. Cureus. 2023 Oct 9;15(10):e46730. doi: 10.7759/cureus.46730. PMID: 38021634; PMCID: PMC10631302. DOI: 10.7759/cureus.46730
27. Palancı Ay Ö, Aktaş S. The effect of maternal functional and postpartum depression status on breastfeeding self-efficacy of the mothers: A cross-sectional study. Health Care Women Int. 2024;45(2):236-250. doi: 10.1080/07399332.2021.1973008. Epub 2021 Sep 23. PMID: 34554055. DOI: 10.1080/07399332.2021.1973008
28. Mohd Shukri NH, Senjaya O, Zainudin Z, Mohamed M, Syed Abdullah FI. The Associations of Breastfeeding and Postnatal Experiences With Postpartum Depression Among Mothers of Hospitalized Infants in Tertiary Hospitals. Cureus. 2022 Sep 21;14(9):e29425. doi: 10.7759/cureus.29425. PMID: 36299949; PMCID: PMC9586844. DOI: 10.7759/cureus.29425
29. Özhüner Y, Özerdoğan N. The effect of psychoeducational ıntervention on postpartum care on postpartum depression and breastfeeding: a randomized controlled trial. BMC Nurs. 2025 Nov 26;24(1):1449. doi: 10.1186/s12912-025-04079-5. PMID: 41299439; PMCID: PMC12659235. DOI: 10.1186/s12912-025-04079-5
30. Islam MJ, Broidy L, Baird K, Rahman M, Zobair KM. Early exclusive breastfeeding cessation and postpartum depression: Assessing the mediating and moderating role of maternal stress and social support. PLoS One. 2021 May 17;16(5):e0251419. doi: 10.1371/journal.pone.0251419. PMID: 33999929; PMCID: PMC8128229. DOI: 10.1371/journal.pone.0251419
31. Stelson EA, Kulkacek L, Frasso R, Hall M, Guevara JP. Perspectives on Breastfeeding from Mothers with Postpartum Depression Symptoms: A Qualitative Assessment of Antecedents, Barriers, Facilitators, and Intervention Suggestions. Breastfeed Med. 2021 Oct;16(10):790-798. doi: 10.1089/bfm.2020.0251. Epub 2021 May 19. PMID: 34010030; PMCID: PMC8817733. DOI: 10.1089/bfm.2020.0251
32. Sim CSM, Chen H, Chong SL, Xia OJ, Chew E, Guo X, Ng LP, Ch'ng YC, Ong JLH, Tan J, Ng DCC, Tan NC, Chan YH. Primary health level screening for postpartum depression during well-child visits: Prevalence, associated risk factors, and breastfeeding. Asian J Psychiatr. 2023 Sep;87:103701. doi: 10.1016/j.ajp.2023.103701. Epub 2023 Jul 18. Erratum in: Asian J Psychiatr. 2023 Dec;90:103829. doi: 10.1016/j.ajp.2023.103829. PMID: 37517174. DOI: 10.1016/j.ajp.2023.103701
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Michalina Janiszewska, Maciej Sobkowiak, Paulina Sobkowiak, Justyna Jusiak, Janusz Łuczak, Justyna Dżumaga, Jeremi Łuczak, Maria Łazik, Roksana Dybowska, Marta Walaszek

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 2
Number of citations: 0