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Journal of Education, Health and Sport

The influence of diet and oral supplementation on female infertility
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  3. Vol. 88 (2026) /
  4. Medical Sciences

The influence of diet and oral supplementation on female infertility

Authors

  • Maciej Krężel Wrocław University of Science and Technology Wybrzeże Stanisława Wyspiańskiego 27, 50-370 Wrocław https://orcid.org/0009-0007-2670-6625
  • Olga Krężel 4. Military Clinical Hospital and Polyclinic IPHC Weigla 5, 53-114 Wrocław https://orcid.org/0009-0007-5687-3440
  • Marcelina Rybińska 4. Military Clinical Hospital and Polyclinic IPHC Weigla 5, 53-114 Wrocław https://orcid.org/0009-0000-1580-8705
  • Artur Szafraniec Lower Silesian Centre for Oncology, Pulmonology and Haematology plac Hirszfelda 12, 53-413 Wrocław https://orcid.org/0000-0002-9991-2039
  • Zuzanna Kalinowska Lower Silesian Centre for Oncology, Pulmonology and Haematology plac Hirszfelda 12, 53-413 Wrocław https://orcid.org/0009-0005-3940-3987

DOI:

https://doi.org/10.12775/JEHS.2026.88.68040

Keywords

infertility, pregnancy, female infertility, diet, lifestyle

Abstract

Infertility is an increasing concern among young couples attempting to conceive. Despite advances in medical treatments, including ovarian stimulation, intrauterine insemination, and in vitro fertilization, the prevalence of infertility remains high, suggesting that multiple factors may interfere with reproductive success. Recent research has highlighted the important role of dietary patterns and oral supplementation in fertility, influencing metabolic health, inflammation, ovulation, and oocyte quality. Modifiable risk factors such as stress, obesity, and unhealthy diet have been associated with reduced pregnancy success. Given their potential impact, further investigation into diet and lifestyle interventions is essential to improve reproductive outcomes.

References

Abadia, L., Gaskins, A. J., Chiu, Y. H., Williams, P. L., Keller, M., Wright, D. L., … Chavarro, J. E. (2017). Female caffeine and alcohol intake in relation to in vitro fertilization outcomes. Fertility and Sterility, 108(6), 1026–1033. https://doi.org/10.1016/j.fertnstert.2017.09.007

Alesi, S., Villani, A., Mantzioris, E., Takele, W. W., Cowan, S., Moran, L. J., & Mousa, A. (2022). Anti-inflammatory diets in fertility: An evidence review. Nutrients, 14(19), 3914. https://doi.org/10.3390/nu14193914

Anagnostis, P., Karras, S., & Goulis, D. G. (2013). Vitamin D in human reproduction: A narrative review. International Journal of Clinical Practice, 67(3), 225–235. https://doi.org/10.1111/ijcp.12031

Anastasi, E., Fuggetta, E., De Vito, C., Migliara, G., Viggiani, V., Manganaro, L., … Porpora, M. G. (2017). Low levels of 25-OH vitamin D in women with endometriosis and associated pelvic pain. Clinical Chemistry and Laboratory Medicine, 55(12), e282–e284. https://doi.org/10.1515/cclm-2017-0016

Augood, C., Duckitt, K., & Templeton, A. A. (1998). Smoking and female infertility: A systematic review and meta-analysis. Human Reproduction, 13(6), 1532–1539. https://doi.org/10.1093/humrep/13.6.1532

Axmon, A., Rylander, L., Strömberg, U., & Hagmar, L. (2002). Female fertility in relation to the consumption of fish contaminated with persistent organochlorine compounds. Scandinavian Journal of Work, Environment & Health, 28(2), 124–132. https://doi.org/10.5271/sjweh.656

Badawy, A., State, O., & Abdelgawad, S. (2007). N-acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary syndrome: A cross-over trial. Acta Obstetricia et Gynecologica Scandinavica, 86(2), 218–222. https://doi.org/10.1080/00016340601090337

Bolúmar, F., Olsen, J., Rebagliato, M., & Bisanti, L. (1997). Caffeine intake and delayed conception: A European multicenter study. American Journal of Epidemiology, 145(4), 324–334. https://doi.org/10.1093/oxfordjournals.aje.a009109

Bosdou, J. K., Konstantinidou, E., Anagnostis, P., Kolibianakis, E. M., & Goulis, D. G. (2019). Vitamin D and obesity: Two interacting players in infertility. Nutrients, 11(7), 1455. https://doi.org/10.3390/nu11071455

Chavarro, J. E., Rich-Edwards, J. W., Rosner, B. A., & Willett, W. C. (2007). Dietary fatty acid intakes and the risk of ovulatory infertility. American Journal of Clinical Nutrition, 85(1), 231–237. https://doi.org/10.1093/ajcn/85.1.231

Chavarro, J. E., Rich-Edwards, J. W., Rosner, B. A., & Willett, W. C. (2008). Use of multivitamins, intake of B vitamins, and risk of ovulatory infertility. Fertility and Sterility, 89(3), 668–676. https://doi.org/10.1016/j.fertnstert.2007.03.089

Chavarro, J. E., Rich-Edwards, J. W., Rosner, B. A., & Willett, W. C. (2009). Dietary carbohydrate quantity and quality and risk of ovulatory infertility. European Journal of Clinical Nutrition, 63(1), 78–86. https://doi.org/10.1038/sj.ejcn.1602904

Chu, J., Gallos, I., Tobias, A., Tan, B., Eapen, A., & Coomarasamy, A. (2018). Vitamin D and assisted reproductive treatment outcome: A systematic review and meta-analysis. Human Reproduction, 33(1), 65–80. https://doi.org/10.1093/humrep/dex326

Ciavattini, A., Serri, M., Delli Carpini, G., Morini, S., & Clemente, N. (2017). Ovarian endometriosis and vitamin D serum levels. Gynecological Endocrinology, 33(2), 164–167. https://doi.org/10.1080/09513590.2016.1239254

Czeizel, A. E., Métneki, J., & Dudás, I. (1996). The effect of preconceptional multivitamin supplementation on fertility. International Journal for Vitamin and Nutrition Research, 66(1), 55–58.

Espino, J., Macedo, M., Lozano, G., Ortiz, Á., Rodríguez, C., Rodríguez, A. B., & Bejarano, I. (2019). Impact of melatonin supplementation in women with unexplained infertility. Antioxidants, 8(9), 338. https://doi.org/10.3390/antiox8090338

Florack, E. I., Zielhuis, G. A., & Rolland, R. (1994). Cigarette smoking, alcohol consumption, and caffeine intake and fecundability. Preventive Medicine, 23(2), 175–180. https://doi.org/10.1006/pmed.1994.1024

Fontana, R., & Della Torre, S. (2016). The deep correlation between energy metabolism and reproduction. Nutrients, 8(2), 87. https://doi.org/10.3390/nu8020087

Gaskins, A. J., Afeiche, M. C., Wright, D. L., Toth, T. L., Williams, P. L., Hauser, R., & Chavarro, J. E. (2014). Dietary folate and reproductive success among women undergoing assisted reproduction. Obstetrics & Gynecology, 124(4), 801–809. https://doi.org/10.1097/AOG.0000000000000477

Gaskins, A. J., Chiu, Y. H., Williams, P. L., Ford, J. B., Toth, T. L., Hauser, R., & Chavarro, J. E. (2015). Association between serum folate and vitamin B-12 and ART outcomes. American Journal of Clinical Nutrition, 102(4), 943–950. https://doi.org/10.3945/ajcn.115.112185

Izquierdo-Condoy, J. S., et al. (2024). Direct health implications of e-cigarette use: A scoping review. Frontiers in Public Health, 12, 1427752. https://doi.org/10.3389/fpubh.2024.1427752

Łakoma, K., Kukharuk, O., & Śliż, D. (2023). Influence of metabolic factors and diet on fertility. Nutrients, 15(5), 1180. https://doi.org/10.3390/nu15051180

Machtinger, R., Gaskins, A. J., Mansur, A., et al. (2017). Preconception beverage intake and IVF outcomes. Fertility and Sterility, 108(6), 1026–1033. https://doi.org/10.1016/j.fertnstert.2017.09.007

Mumford, S. L., et al. (2016). Dietary fat intake and reproductive hormones. American Journal of Clinical Nutrition, 103(3), 868–877. https://doi.org/10.3945/ajcn.115.119321

Pacchiarotti, A., Carlomagno, G., Antonini, G., & Pacchiarotti, A. (2016). Myo-inositol and melatonin in IVF. Gynecological Endocrinology, 32(1), 69–73. https://doi.org/10.3109/09513590.2015.1101444

Schliep, K. C., et al. (2013). Energy-containing beverages and ovarian function. American Journal of Clinical Nutrition, 97(3), 621–630. https://doi.org/10.3945/ajcn.111.024752

Showell, M. G., Brown, J., Clarke, J., & Hart, R. J. (2013). Antioxidants for female subfertility. Cochrane Database of Systematic Reviews, CD007807. https://doi.org/10.1002/14651858.CD007807.pub2

Silvestris, E., Lovero, D., & Palmirotta, R. (2019). Nutrition and female fertility. Frontiers in Endocrinology, 10, 346. https://doi.org/10.3389/fendo.2019.00346

Skoracka, K., Ratajczak, A. E., Rychter, A. M., Dobrowolska, A., & Krela-Kaźmierczak, I. (2021). Female fertility and the nutritional approach. Advances in Nutrition, 12(6), 2372–2386. https://doi.org/10.1093/advances/nmab068

Sturmey, R. G., Reis, A., Leese, H. J., & McEvoy, T. G. (2009). Role of fatty acids in oocyte maturation. Reproduction in Domestic Animals, 44(Suppl 3), 50–58. https://doi.org/10.1111/j.1439-0531.2009.01402.x

Szymański, W., & Kazdepka-Ziemińska, A. (2003). Effect of homocysteine on oocyte maturity. Ginekologia Polska, 74(10), 1392–1396.

Vanegas, J. C., et al. (2015). Soy food intake and ART outcomes. Fertility and Sterility, 103(3), 749–755.e2. https://doi.org/10.1016/j.fertnstert.2014.12.104

Wathes, D. C., Abayasekara, D. R., & Aitken, R. J. (2007). Polyunsaturated fatty acids in reproduction. Biology of Reproduction, 77(2), 190–201. https://doi.org/10.1095/biolreprod.107.060558

Weiss, G., Goldsmith, L. T., Taylor, R. N., Bellet, D., & Taylor, H. S. (2009). Inflammation in reproductive disorders. Reproductive Sciences, 16(2), 216–229. https://doi.org/10.1177/1933719108330087

Westphal, L. M., Polan, M. L., & Trant, A. S. (2006). FertilityBlend supplementation and fertility. Clinical and Experimental Obstetrics & Gynecology, 33(4), 205–208.

Wilcox, A., Weinberg, C., & Baird, D. (1988). Caffeinated beverages and decreased fertility. The Lancet, 2(8626–8627), 1453–1456. https://doi.org/10.1016/S0140-6736(88)90933-6

Willis, S. K., Wise, L. A., Wesselink, A. K., et al. (2020). Glycemic load and fecundability. American Journal of Clinical Nutrition, 112(1), 27–38. https://doi.org/10.1093/ajcn/nqz312

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Published

2026-02-14

How to Cite

1.
KRĘŻEL, Maciej, KRĘŻEL, Olga, RYBIŃSKA, Marcelina, SZAFRANIEC, Artur and KALINOWSKA, Zuzanna. The influence of diet and oral supplementation on female infertility. Journal of Education, Health and Sport. Online. 14 February 2026. Vol. 88, p. 68040. [Accessed 15 February 2026]. DOI 10.12775/JEHS.2026.88.68040.
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Vol. 88 (2026)

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Medical Sciences

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Copyright (c) 2026 Maciej Krężel, Olga Krężel, Marcelina Rybińska, Artur Szafraniec, Zuzanna Kalinowska

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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