Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss

Authors

  • O. P. Matviychuk National University of Pharmacy
  • A. V. Matviychuk National University of Pharmacy
  • A. V. Taran National University of Pharmacy

Keywords

benofilin, acute kidney damage, diuretic, nephroprotective activity, rats

Abstract

Effect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damage resulting in acute renal failure (ARF). As a result of the application of benofilin its ability is established to prevent the death of animals in the first day of the experiment. By the ability to prevent impaired kidney function in rats benofilin exceeds the effect of the hofitol.

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Published

2019-02-28

How to Cite

1.
MATVIYCHUK, O. P., MATVIYCHUK, A. V. and TARAN, A. V. Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss. Journal of Education, Health and Sport. Online. 28 February 2019. Vol. 9, no. 2, pp. 493-499. [Accessed 28 June 2025].

Issue

Vol. 9 No. 2 (2019)

Section

Research Articles

License

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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