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Journal of Education, Health and Sport

Clinical and morphological features actinic keratosis
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  3. Vol. 79 (2025) /
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Clinical and morphological features actinic keratosis

Authors

  • O. Bondar Odesa National Medical University

DOI:

https://doi.org/10.12775/JEHS.2025.79.60772

Keywords

actinic keratosis, clinic, morphology, inflammation, diagnosis, treatment

Abstract

The article presents the clinical and morphological characteristics of different variants of actinic keratosis in 20 patients. It was found that in 18 (90.0%) patients, lesions were localized exclusively to exposed skin areas (face, neck, and back of the hands), while in 2 (10.0%) cases, the rash also appeared on the upper and lower extremities and back. The average patient age was 66.5±3.4 years. Morphologically, 7 cases of hypertrophic, 9 cases of atrophic, and 4 cases of Bowenoid actinic keratosis were diagnosed. The Bowenoid type showed no histological differences from Bowen’s disease. Regardless of the histological variant, the dermis exhibited basophilic collagen degeneration and a dense inflammatory infiltrate, predominantly consisting of lymphocytes.

References

1. Gutzmer R, Wiegand S, Kölbl O, Wermker K, Heppt M, Berking C. Actinic Keratosis and Cutaneous Squamous Cell Carcinoma. Dtsch Arztebl Int. 2019; 116(37): 616-626. doi: 10.3238/arztebl.2019.0616.

2. Phansuk K, Vachiramon V, Jurairattanaporn N, Chanprapaph K, Rattananukrom T. Dermal Pathology in Melasma: An Update Review. Clin Cosmet Investig Dermatol. 2022; 15: 11-19. doi: 10.2147/CCID.S343332.

3. Arcuri D, Ramchatesingh B, Lagacé F, Iannattone L, Netchiporouk E, Lefrançois P, Litvinov IV. Pharmacological Agents Used in the Prevention and Treatment of Actinic Keratosis: A Review. Int J Mol Sci. 2023; 24(5): 4989. doi: 10.3390/ijms24054989.

4. Selezneva EA, Khlebnikova AN. Modern approaches to the prevention of actinic keratosis. Aesthetic medicine. 2010; 3: 267-273. [In Russian]

5. Lever’s histopathology of the skin. – 8th ed. /Ed. In chief, D.Elder; associated eds, R.Elenitsas, Ch.Jaworsky, B.Johnson, Jr. – Philadelphia-New York: Lippincott-Raven Publishers. 1997: 1073.

6. Hurwitz RM, Monger .E. Solar keratosis: an envolving squamous cell carcinoma [letter]. Dermatol Surg. 1995; 21: 183.

7. Akimov VG, Bratseva EV. Modern methods of treatment of actinic keratosis. Bull Dermatol Venereol. 2008; 2: 43-48. [In Russian]

8. Sinclair R, Baker C, Spelman L, Supranowicz M, MacMahon B. A review of actinic keratosis, skin field cancerisation and the efficacy of topical therapies. Australas J Dermatol. 2021; 62(2): 119-123. doi: 10.1111/ajd.13447

9. Sgouros D, Milia-Argyti A, Arvanitis DK, Polychronaki E, Kousta F, Panagiotopoulos A. et al. Actinic Keratoses (AK): An Exploratory Questionnaire-Based Study of Patients' Illness Perceptions. Curr Oncol. 2022; 29(7): 5150-5163. doi: 10.3390/curroncol29070408.

10. Kovneristy AE, Kolyadenko VG, Kolyadenko EV, Ruzicka T, Stege H. Actinic keratosis as a preinvasive carcinoma. Ukr J Dermatol Venereol Cosmetol. 2005; 1: 27-32. [In Russian]

11. Dumanskyi YV, Chehun VF. Oncology in Ukraine: the state of the problem and ways of development. Oncology. 2022; 24(3): 1-6. [In Ukrainian]

12. Nikogosyan LR, Matyashchuk NM, Rybin AI. Implementation of the modern WHO cancer prevention strategy in Odessa: a new platform and ways of implementation. Clinical Oncology. 2024; 14(1): 79-83

13. Zapolsky ME, Lebedyuk MM, Prokofieva NB, Teplyuk YV, Zapolskaya DM. A modern view on the problem of erythematous facial conditions in rosacea. Odessa Medical Journal. 2022; 1–2(179–180): 60-63. [In Ukrainian]

14. Moroz VM, Shandra OA, Vastyanov RS, Yoltukhivsky MV, Omelchenko OD. Physiology. Vinnytsia: Nova Knyha. 2016. 722.

15. Lund A.W., Medler T.R., Leachman S.A., Coussens L.M. Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer. Cancer Discov. 2016; 6(1): 22-35.

16. Munn L.L. Cancer and inflammation. Wiley Interdiscip Rev Syst Biol Med. 2017; 9(2):10.1002/wsbm.1370. doi: 10.1002/wsbm.1370.

17. Vastyanov RS, Stoyanov OM, Babienko VV, Hruzevskiy OA, Talalayev KO, Kirchev VV. et al. Plasma rich platelets anti-inflammatory effect in conditions of carrageenan-induced paw edema in rats. World of Medicine and Biology. 2024; 4(90): 170-175. doi: 10.26724/2079-8334-2024-4-90-170-175

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Published

2025-03-28

How to Cite

1.
BONDAR, O. Clinical and morphological features actinic keratosis. Journal of Education, Health and Sport. Online. 28 March 2025. Vol. 79, p. 60772. [Accessed 28 June 2025]. DOI 10.12775/JEHS.2025.79.60772.
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Issue

Vol. 79 (2025)

Section

Medical Sciences

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Copyright (c) 2025 O. Bondar

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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