Impact of climate change on the spread of infectious diseases - review
DOI:
https://doi.org/10.12775/JEHS.2025.82.60532Keywords
emerging infectious diseases, climate change, transmission, outbreak, early diagnosisAbstract
Advances in sanitation, broader access to healthcare, and developments in preventive and clinical medicine have contributed to reducing mortality and morbidity from many infectious diseases. Nevertheless, recent outbreaks of emerging infectious diseases (EIDs) have caused significant health losses, and their frequency is likely to increase due to the impact of climate change on pathogens, the environment, and populations. Extreme or prolonged changes in temperature, precipitation, humidity, and air pollution resulting from climate change can, for example, expand the range of EID reservoirs, increase host–pathogen and cross-species interactions, and degrade the health of susceptible populations, thereby promoting new EID outbreaks.
It is therefore crucial to establish global strategies for tracking and modeling potential EID responses to predict their future behavior and guide research on early detection, diagnostics, and vaccine development. Multi-disciplinary, intercontinental collaborations are essential to develop effective surveillance and modeling platforms that leverage artificial intelligence to mitigate the effects of climate change on EID outbreaks. In this article I discuss how climate change elevates the risk of EIDs, present novel approaches to enhancing the surveillance of emerging pathogens that pose epidemic threats, analyze both existing and new measures to contain or reduce the risk of future EID outbreaks, and describe advanced methods for tracking EIDs during outbreaks to limit their transmission.
References
1. Jones KE, Patel NG, Levy MA, et al. Global trends in emerging infectious diseases. Nature. 2008;451(7181):990.
2. WHO. 2023. Available from: https://covid19.who.int/.
3. Zhang XX, Jin YZ, Lu YH, et al. Infectious disease control: from health security strengthening to health systems improvement at global level. Glob Health Res Policy. 2023;8(1):38.
4. Neira M, Erguler K, Ahmady-Birgani H, Al-Hmoud ND, Fears R, Gogos C, Hobbhahn N, Koliou M, Kostrikis LG, Lelieveld J, Majeed A, Paz S, Rudich Y, Saad-Hussein A, Shaheen M, Tobias A, Christophides G. Climate change and human health in the Eastern Mediterranean and Middle East: Literature review, research priorities and policy suggestions. Environ Res. 2023 Jan 1;216(Pt 2):114537.
5. Semenza JC, Paz S.. Climate change and infectious disease in Europe: impact, projection and adaptation. Lancet Reg Health Eur. 2021;9:100230.
6. Seidel D, Wurster S, Jenks JD, Sati H, Gangneux JP, Egger M, Alastruey-Izquierdo A, Ford NP, Chowdhary A, Sprute R, Cornely O, Thompson GR 3rd, Hoenigl M, Kontoyiannis DP. Impact of climate change and natural disasters on fungal infections. Lancet Microbe. 2024 Jun;5(6):e594-e605.
7. Morens DM, Folkers GK, Fauci AS.. The challenge of emerging and re-emerging infectious diseases. Nature. 2004;430(6996):242–249.
8. Tidman R, Abela-Ridder B, de Castaneda RR.. The impact of climate change on neglected tropical diseases: a systematic review. Trans R Soc Trop Med Hyg. 2021;115(2):147–168.
9. Li Y, Reeves RM, Wang X, et al. Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis. Lancet Glob Health. 2019;7(8):e1031–e1045.
10. Mordecai EA, Caldwell JM, Grossman MK, et al. Thermal biology of mosquito-borne disease. Ecol Lett. 2019;22(10):1690–1708.
11. Lian X, Huang J, Li H, et al. Heat waves accelerate the spread of infectious diseases. Environ Res. 2023;231(Pt 2):116090.
12. Wenzel RP. A new hantavirus infection in North America. N Engl J Med. 1994;330(14):1004–1005.
13. Lau CL, Smythe LD, Craig SB, et al. Climate change, flooding, urbanisation and leptospirosis: fuelling the fire? Trans R Soc Trop Med Hyg. 2010;104(10):631–638.
14. Moore SM, Azman AS, Zaitchik BF, et al. El Nino and the shifting geography of cholera in Africa. Proc Natl Acad Sci U S A. 2017;114(17):4436–4441.
15. Guernier V, Hochberg ME, Guegan JF.. Ecology drives the worldwide distribution of human diseases. PLoS Biol. 2004;2(6):e141.
16. Becker DJ, Albery GF, Sjodin AR, et al. Optimising predictive models to prioritise viral discovery in zoonotic reservoirs. Lancet Microb. 2022;3(8):e625–e637.
17. Rocklöv J, Dubrow R.. Climate change: an enduring challenge for vector-borne disease prevention and control. Nat Immunol 2020;21(5):479–483.
18. Franklinos LHV, Jones KE, Redding DW, et al. The effect of global change on mosquito-borne disease. Lancet Infect Dis. 2019;19(9):e302–e312.
19. Levy K, Smith SM, Carlton EJ. Climate Change Impacts on Waterborne Diseases: Moving Toward Designing Interventions. Curr Environ Health Rep. 2018 Jun;5(2):272-282.
20. Tran HM, Tsai F-J, Lee Y-L, et al. The impact of air pollution on respiratory diseases in an era of climate change: a review of the current evidence. Sci Total Environ. 2023;898:166340.
21. Sun S, Chang Q, He J, et al. The association between air pollutants, meteorological factors and tuberculosis cases in Beijing, China: a seven-year time series study. Environ Res 2023;216:114581.
22. Zhu N, Zhang DY, Wang WL, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–733.
23. Novel 2019 coronavirus genome. 2023. Available from: https://virological.org/t/novel-2019-coronavirus-genome/319.
24. Rambaut A, Holmes EC, O'Toole A, et al. A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology. Nat Microbiol. 2020;5(11):1403–1407.
25. Gangavarapu K, Latif AA, Mullen JL, et al. Outbreak.info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations. Nat Methods. 2023;20(4):512–522.
26. Grubaugh ND, Ladner JT, Kraemer MUG, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. Nature. 2017;546(7658):401.
27. Daniloski Z, Jordan TX, Wessels HH, et al. Identification of required host factors for SARS-CoV-2 infection in human cells. Cell. 2021;184(1):92–105.
28. Li M, Guo MC, Peng Y, et al. High proportion of tuberculosis transmission among social contacts in rural China: a 12-year prospective population-based genomic epidemiological study. Emerg Microbes Infect. 2022;11(1):2102–2111.
29. Boulos MN, Roudsari AV, Carson ER.. Health geomatics: an enabling suite of technologies in health and healthcare. J Biomed Inform. 2001;34(3):195–219.
30. Lyseen AK, Nohr C, Sorensen EM, et al. A review and framework for categorizing current research and development in health related geographical information systems (gis) studies. Yearb Med Inform. 2014;9(1):110–124.
31. Boulos MN. Location-based health information services: a new paradigm in personalised information delivery. Int J Health Geogr. 2003;2:2.
32. De Souza MLM, Lopes GA, Branco AC, et al. Leprosy screening based on artificial Intelligence: development of a cross-platform app. JMIR Mhealth Uhealth. 2021;9(4):e23718.
33. Keutzer L, Wicha SG, Simonsson US.. Mobile health apps for improvement of tuberculosis treatment: descriptive review. JMIR Mhealth Uhealth. 2020;8(4):e17246.
34. Sharpe JD, Kamara MT.. A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis. Sex Health. 2018;15(6):587–594.
35. Pascucci M, Royer G, Adamek J, et al. AI-based mobile application to fight antibiotic resistance. Nat Commun. 2021;12(1):1173.
36. Patel SK, Surve J, Parmar J, et al. Recent advances in biosensors for detection of COVID-19 and other viruses. IEEE Rev Biomed Eng. 2023;16:22–37.
37. Tran NK, Albahra S, Rashidi H, et al. Innovations in infectious disease testing: leveraging COVID-19 pandemic technologies for the future. Clin Biochem 2023;117:10–15.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Martyna Lecka, Małgorzata Omyła, Edyta Pietryszak, Marcel Paruzel

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 12
Number of citations: 0