Modern Approaches to the Diagnosis and Treatment of Lower Urinary Tract Disorders
DOI:
https://doi.org/10.12775/JEHS.2025.82.60280Keywords
overactive bladder (OAB), stress urinary incontinence (SUI), nocturia, lower urinary tract symptoms (LUTS), β3-adrenergic receptor agonistsAbstract
Lower urinary tract disorders, including conditions such as overactive bladder (OAB), stress urinary incontinence (SUI), neurogenic voiding dysfunction, and nocturia, represent a significant health concern that greatly affects patients’ quality of life worldwide. These disorders not only diminish life comfort but can also lead to physical and psychological complications, including chronic pain, urinary tract infections, sleep disturbances, depression, and social isolation. It is estimated that these conditions affect both adults and children, with prevalence rates ranging from 1% to 20% in pediatric populations and up to 67% among older adults.
Modern medicine offers a variety of treatment options for lower urinary tract disorders, including pharmacotherapy, behavioral therapies, surgical interventions, and advanced technological approaches such as neuromodulation. Advances in the understanding of the pathophysiology of these conditions, along with the development of medical technologies, have significantly improved diagnostic and therapeutic capabilities. Nonetheless, managing patients with lower urinary tract disorders remains a clinical challenge, particularly for those with treatment-resistant symptoms who do not respond to conventional therapies.
References
1. Carter, E., Hall, R., Ajoku, K., & Kearney, R. (2023). Is caesarean section protective against anal incontinence in women after obstetric anal sphincter injury (OASI)? A systematic review and meta-analysis. ICS 2023 Toronto Abstracts, 2023, 100719.
2. Laude, M., Bailly, L., Fabre, R., et al. (2023). Long-term midurethral mesh sling survival for women with stress urinary incontinence. ICS 2023 Toronto Abstracts, 2023, 100735.
3. Sobh, A., Elkashef, A., Hussiny, M., Anas, M., & Helmy, T. (2023). Concomitant anterior and posterior urethral valves: An uncommon association. ICS 2023 Toronto Abstracts, 2023, 100786.
4. Kitta, T., Mitsui, T., & Izumi, N. (2023). Importance of regular examination and follow-up for long-term prognosis in pediatric neurogenic bladder patients: 24 months follow-up data. ICS 2023 Toronto Abstracts, 2023, 100784.
5. Hadir, S., Idam, H., Madjidanem, P., Kyal, N., Lmidmani, F., & El Fatimi, A. (2023). Nocturnal enuresis in children: Caregiver’s burden and psychological health. ICS 2023 Toronto Abstracts, 2023, 100783.
6. Santoso, A., Sunaert, S., & De Ridder, D. (2023). The dynamic of brain activation during urge perception: Robust findings from sensation-driven functional MRI study. ICS 2023 Toronto Abstracts, 2023, 100740.
7. Malallah, M., AlAbbad, A., Almousa, R., Cameron, A., Metcalfe, P., & AlSannan, B. (2023). Percutaneous tibial nerve stimulation in children with lower urinary tract dysfunctions: A literature review. ICS 2023 Toronto Abstracts, 2023, 100783.
8. Wilks, S., Rahimi, N., Carugo, D., Somani, B., Smith, D., & Mosayyebi, A. (2023). A multi-technique approach to understanding the impact of biofilms on ureteric/ureteral stents. ICS 2023 Toronto Abstracts, 2023, 100732.
9. Siafarikas, F., Halle, T., Stær-Jensen, J., Bø, K., & Ellström-Engh, M. (2023). Levator muscle avulsion from six weeks to 8 years after first delivery: A longitudinal ultrasound study. ICS 2023 Toronto Abstracts, 2023, 100720.
10. Padmanabhan, P., Zwaans, B., Boldt, R., & Wu, C. (2023). Percutaneous tibial nerve stimulation initial therapy compliance and subsequent third-line treatment patterns. ICS 2023 Toronto Abstracts, 2023, 100744.
11. Brooks, T., & Keevil, C. W. (1997). A simple artificial urine for the growth of urinary pathogens. Letters in Applied Microbiology, 24(3), 203–206.
12. Lo, E., Nicolle, L. E., Coffin, S. E., et al. (2014). Strategies to prevent catheter-associated urinary tract infections in acute care hospitals: 2014 update. Infection Control and Hospital Epidemiology, 35(Suppl 2), S32–S47.
13. Teodorescu, M., & Bercea, M. (2015). Poly(vinylpyrrolidone) – A versatile polymer for biomedical and beyond medical applications. Polymer-Plastics Technology and Engineering, 54(9), 923–943.
14. Wilson, M. L., & Gaido, L. (2004). Laboratory diagnosis of urinary tract infections in adult patients. Clinical Infectious Diseases, 38(8), 1150–1158.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Jakub Buczkowski, Weronika Biaduń, Mateusz Dobosz, Aleksandra Romanowska, Aleksandra Padkowska, Kinga Rogowska, Michał Borawski, Aleksandra Ciuła, Klaudia Arciszewska, Jakub Maciej Pieniążek

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 171
Number of citations: 0