Dengue virus infection in a course of typhoid fever

Abstract

Dengue is a mosquito-borne viral infection caused by dengue virus (DENV) belonging to a group of Flaviviridae. Disease is widely spread in tropical and subtropical regions of Southeast Asia, Africa and the Americas. DENV infection causes a spectrum of illness including flu-like syndrome and potentially life-threatening dengue hemorrhagic fever. Confirmation of DENV infection requires serological serum tests or detection of viral genetic material in a serum sample. There no specific treatment for dengue but symptomatic therapy should be implemented in all cases. Recently there are two modern DENV vaccines available for the people living in the countries at a risk of infection. Efficiency and safety profile of both vaccines are debatable. Dengue symptoms may imitate clinical picture of other diseases that are typical for endemic DENV regions. We present a case of 22-year-old Indonesian woman treated originally due to typhoid fever who develop the symptoms of DENV infection.