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Journal of Education, Health and Sport

Association between ACTN3 gene polymorphism and muscle strength in older adults
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Association between ACTN3 gene polymorphism and muscle strength in older adults

Authors

  • Sylwester Kłoska Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Anna Marciniak Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Marcin Woźniak Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Radosław Perkowski Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Marta Podhorecka Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Dominika Gębka Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Joanna Androsiuk-Perkowska Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Sławomir  Kujawski Faculty of Health Sciences, Department of Hygiene, Epidemiology and Ergonomics, Division of Ergonomics and Exercise Physiology, Nicolaus Copernicus University in Toruń
  • Marcin Kożuchowski Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Henryk Kozłowski Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Kornelia Kędziora-Kornatowska Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Walery Zukow Department of Spatial Management and Tourism, Faculty of Earth Sciences, Nicolaus Copernicus University in Torun, Torun

Keywords

sport geneticsł ACTN3ł older adultsł geriatric patient

Abstract

The decrease of muscle strength and general physical fitness is a big problem in the elderly group. It often prevents the proper functioning of a person, which makes him/her dependent on caretakers. It is believed that the some polymorphisms in ACTN3 geneare associated with better results in strength sports. If those polymorphisms affect muscle strength, they may also be related to the health condition of older people. Our study was conducted on a group of 60 people over 60 years of age. The relationship between overall fitness and muscular strength of elderly patients with ACTN R577X gene polymorphism was checked. The ACTN3 gene was tested by PCR-RFLP. Overall fitness was tested using the IPAQ questionnaire and fitness tests: Tinetti, DGI, Up&Go, SPPB, standing on one leg (both right and left). Based on the results of the survey, the MET and BMI coefficients were determined. It was found that the RX genotype is associated with better results achieved in the SPPB test. Genotype XX was associated with worse results in the right leg standing test (p<0.05). The R-allele of the ACTN3 gene wasassociated with better results obtained during the standing test on the right leg (p<0.05).Based on obtained results it was impossible to determine a clear impact of the ACTN3 gene on muscle strength and health of the older adults.

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Published

2018-08-14

How to Cite

1.
KŁOSKA, Sylwester, MARCINIAK, Anna, WOŹNIAK, Marcin, PERKOWSKI, Radosław, PODHORECKA, Marta, GĘBKA, Dominika, ANDROSIUK-PERKOWSKA, Joanna, KUJAWSKI, Sławomir , KOŻUCHOWSKI, Marcin, KOZŁOWSKI, Henryk, KĘDZIORA-KORNATOWSKA, Kornelia and ZUKOW, Walery. Association between ACTN3 gene polymorphism and muscle strength in older adults. Journal of Education, Health and Sport. Online. 14 August 2018. Vol. 8, no. 9, pp. 155-165. [Accessed 12 May 2025].
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Issue

Vol. 8 No. 9 (2018)

Section

Research Articles

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The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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