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Journal of Education, Health and Sport

ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age
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ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age

Authors

  • Anna Marciniak Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Sylwester Kłoska Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Marcin Woźniak Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Radosław Perkowski Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Marta Podhorecka Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Dominika Gębka Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Joanna Androsiuk-Perkowska Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Henryk Kozłowski Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Kornelia Kędziora-Kornatowska Faculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University Toruń
  • Walery Zukow Department of Spatial Management and Tourism, Faculty of Earth Sciences, Nicolaus Copernicus University in Torun, Torun

Keywords

ACE, older adults, physical performance tests, sport genetics

Abstract

Among older people, a big problem is the decrease in both muscle strength and general physical fitness. This often prevents the proper functioning of a person, which makes him or her dependent on their guardians or family. It is believed that the ACE gene is associated with better results achieved in strength sports. It may also be related to the health condition of older people. For this purpose, a study was conducted on a group of 60 people over 60 years of age. The study was conducted with the consent of the bioethical commission and under the supervision of physiotherapists. The relationship between overall fitness and muscle strength of older people with ACE genotypic variants was checked. For this purpose, a questionnaire on physical activity of IPAQ was used. On its basis, the values ​​of MET and BMI coefficients were determined. Fitness tests were also carried out, i.e. SPPB, DGI and Up & Go. The ACE gene was tested by PCR. The insertion-deletion polymorphism of the Alu sequence in this gene was examined. It was found that: DD gene genotype ACE is associated with higher values ​​of BMI and shorter standing time on the left leg (p<0.05), genotype II is associated with lower overall physical activity determined on the basis of MET (p<0.05), genotype ID is associated with better results in the left leg test (p<0.05). Based on obtained results it is impossible to determine if ACE gene has clear impact on muscle strength and health of the older adults.

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Published

2018-08-14

How to Cite

1.
MARCINIAK, Anna, KŁOSKA, Sylwester, WOŹNIAK, Marcin, PERKOWSKI, Radosław, PODHORECKA, Marta, GĘBKA, Dominika, ANDROSIUK-PERKOWSKA, Joanna, KOZŁOWSKI, Henryk, KĘDZIORA-KORNATOWSKA, Kornelia and ZUKOW, Walery. ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age. Journal of Education, Health and Sport. Online. 14 August 2018. Vol. 8, no. 9, pp. 146-154. [Accessed 12 May 2025].
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Issue

Vol. 8 No. 9 (2018)

Section

Research Articles

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The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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