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Journal of Education, Health and Sport

Amyotrophic lateral sclerosis – aetiology, diagnostics and multidirectional, team, long-term care
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Amyotrophic lateral sclerosis – aetiology, diagnostics and multidirectional, team, long-term care

Authors

  • Kamila Tuzim Chair and Department of Clinical Pathomorphology of the Medical University of Lublin
  • Tomasz Tuzim Sanus Specialist Hospital, ul. Wojska Polskiego 4, Stalowa Wola, Poland;
  • Magdalena Urbańczuk Chair and Department of Clinical Pathomorphology of the Medical University of Lublin, ul. Jaczewskiego 8b, Lublin 20-090, Poland;
  • Marcin Urbańczuk Chair and Department of Family Medicine of the Medical University of Lublin, ul. Langiewicza 6 a, Lublin 20-032, Poland;
  • Katarzyna Schab Chair and Department of Clinical Immunology of the Medical University of Lublin, ul. Chodźki 4 a, Lublin 20-093, Poland;

Keywords

amyotrophic lateral sclerosis, ALS, electrophysiological examination, riluzole, edaravone, replacement ventilation.

Abstract

Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease of brain motoneurons and spinal cord. The incidence rate of this completely incurable condition amounts to 3 to 5 patients per 100,000 inhabitants and its characteristic feature is progressing muscle weakening that leads to respiratory muscle paralysis and death within 3-4 years. Up to now, etiopathogenesis of ALS is unknown, however, more and more often the role of genotype interaction with environmental factors is suggested. Diagnosing ALS is still based on a correlation of interview and clinical picture with the results of diagnostic imaging, electrophysiological examinations and some serological tests. Despite an enormous progress that occurred in neurobiology and molecular genetics, an effective pharmacotherapy inhibiting the development of the disease has not been developed yet, and the treatment is exclusively based on a systematic symptomatic management. Due to the above, ALS treatment is still a great challenge both for the scientists and clinicians.

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Published

2018-08-11

How to Cite

1.
TUZIM, Kamila, TUZIM, Tomasz, URBAŃCZUK, Magdalena, URBAŃCZUK, Marcin & SCHAB, Katarzyna. Amyotrophic lateral sclerosis – aetiology, diagnostics and multidirectional, team, long-term care. Journal of Education, Health and Sport [online]. 11 August 2018, T. 8, nr 8, s. 650–657. [accessed 31.3.2023].
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Issue

Vol. 8 No. 8 (2018)

Section

Review Articles

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The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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