Humanities
Skip to main content Skip to main navigation menu Skip to site footer
  • Register
  • Login
  • Menu
  • Home
  • Current
  • Archives
  • Announcements
  • About
    • About the Journal
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Register
  • Login

Journal of Education, Health and Sport

Analysis of poisoning with OTC drugs for suicidal purposes among children and adolescents in Poland in the period 2012 - 2023: Paracetamol as the most frequently used substance in intentional poisonings
  • Home
  • /
  • Analysis of poisoning with OTC drugs for suicidal purposes among children and adolescents in Poland in the period 2012 - 2023: Paracetamol as the most frequently used substance in intentional poisonings
  1. Home /
  2. Archives /
  3. Vol. 78 (2025) /
  4. Medical Sciences

Analysis of poisoning with OTC drugs for suicidal purposes among children and adolescents in Poland in the period 2012 - 2023

Paracetamol as the most frequently used substance in intentional poisonings

Authors

  • Maria Kubicka Faculty of Medicine, Wroclaw Medical University, Wybrzeże L. Pasteura 1, 50-367 Wroclaw, Poland https://orcid.org/0000-0001-6913-9914
  • Paulina Polańska https://orcid.org/0009-0004-2365-7977
  • Marta Gruszka Military Clinical Hospital in Wrocław, Weigla 5, 53-114 Wrocław, Poland https://orcid.org/0009-0003-0775-3451
  • Martyna Zakrocka Lower Silesian Oncology, Pulmonology and Hematology Center, pl. Ludwika Hirszfelda 12, 53-413 Wroclaw, Poland https://orcid.org/0009-0004-5091-5919

DOI:

https://doi.org/10.12775/JEHS.2025.78.57622

Keywords

suicide attempt, paracetamol, poisoning

Abstract

Introduction and Purpose: Drug poisoning among children and adolescents is an increasing public health issue worldwide and in Poland. Intentional poisonings, especially suicide attempts, are on the rise, often involving over-the-counter (OTC) medications, with paracetamol being the most commonly used substance. This paper aims to analyze the prevalence, characteristics, and implications of drug poisonings in youth, focusing on social and mental health factors, particularly during the COVID-19 pandemic.

Materials and Methods: The study is based on retrospective data collected from Polish cities published between 2014 and 2023, examining hospital admissions, demographic trends, and poisoning agents.

Results: The study reveals a significant increase in suicide attempts, especially during the COVID-19 pandemic. Paracetamol poisoning remains the leading cause of intentional overdoses, with severe cases potentially resulting in acute liver failure or death if untreated. Girls account for a disproportionate number of cases, and many adolescents who attempt suicide lack prior psychiatric diagnoses. Seasonal trends and shifts in age demographics suggest changing patterns in poisoning incidents.

Conclusions: The findings emphasize the need for improved mental health education, early intervention, and caregiver awareness. Strengthening psychological support and implementing stricter regulation of OTC drugs are crucial to addressing the root causes of youth suicide attempts. Proactive measures, such as teaching problem-solving skills and expanding access to mental health services, are essential to mitigating this growing public health challenge.

References

[1] Gumprecht K. Zatrucia. Wybrane zagadnienia z intensywnej terapii dziecięcej. 2nd ed. Śląski Uniwersytet Medyczny w Katowicach. 2011;105

[2] Suchecka D, Kucharska-Mazur J, Groszewska K, Mak M, Samochowiec J, Samochowiec A. Analysis of the phenomenon of over-the-counter drug abuse and not controlled herbs trade by polish adolescents: Part I. Med Pr. 2017;68(3):413-422. https://doi.org/10.13075/mp.5893.00245

[3] Meszaros-Tutak A. Leki stosowane w przeziębieniu. Przewodnik Lekarza/Guide for GPs. 2001;18-21.

[4] Tomaszek L, Soń M. Przyczyny występowania zatruć u pacjentów leczonych na oddziale toksykologii. State and Society XXII: 2022, 1. https://doi.org/10.48269/2451-0858-pis-2022-1-006

[5] Tomaszek L, Kurleto P, Turkanik E, Bielec E, Milaniak I, Dąbrowska-Mędrzycka W. Demographic and clinical profile of adolescents suicide attempters admitted to an emergency department during the COVID-19 pandemic - a retrospective cohort study using hospital information system. Front Psychiatry. 2024;15:1422008. Published 2024 Jun 17. https://doi.org/10.3389/fpsyt.2024.1422008

[6] Jackowska T, Grzelczyk-Wielgórska M. Acute poisoning as a cause of hospitalization of children and adolescents in the pediatric ward – 9-year analysis. Borgis - Advances in Medical Sciences 92014; 628-632

[7] Portal gov.pl. Suicidal behaviour among children and young people. Report for 2012-2021 based on data from the National Police Headquarters. 2022. https://www.gov.pl/attachment/82261ed5-8c47-4ab7-9241-18fca8ea75ab (Access: 03.01.2025)

[8] Milewska E. Epidemiological situation of acute poisonings of children aged 9-18 years hospitalized in the Suwałki Regional Hospital in 2013-2018. Retrospective analysis. Repository of Medical University of Bialystok. 2019

[9] Sosnowska W. Brzozowska A. Analysis of poisonings in patients up to 18 years old hospitalized in the Clinical Department of Toxicology and Cardiology in Stefan Wyszyński Regional Specialist Hospital in Lublin in 2022. Journal of Education Health and Sport 14(1):79-89 https://doi.org/10.12775/JEHS.2023.14.01.009

[10] Farah R, Rege SV, Cole RJ, Holstege CP. Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10–19 Years During the COVID-19 Pandemic — United States, 2020–2022. MMWR Morb Mortal Wkly Rep 2023;72:426–430. http://dx.doi.org/10.15585/mmwr.mm7216a3

[11] Mayo Clinic. COVID-19 and your mental health. 2024. https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/mental-health-covid-19/art-20482731?utm_source=chatgpt.com (Access: 02.01.2025)

[12] Penna A, Buchanan N. Paracetamol poisoning in children and hepatotoxicity. Br J Clin Pharmacol. 1991;32(2):143-149. https://doi.org/10.1111/j.1365-2125.1991.tb03873.x

[13] Verbić A. Paracetamol poisoning in children. Medicina Fluminensis. 2016. 52(4). https://doi.org/10.21860/medflum2016_4ver

[14] Uwumiro F, Okpujie V, Olaomi OA, et al. Profile of Childhood Poisoning and Its Outcomes in the United States: A One-Year Nationwide Study of Emergency and Inpatient Admissions. Cureus. 2023;15(4):e37452. Published 2023 Apr 11. https://doi.org/10.7759/cureus.37452

[15] Pilarska I, Grabska K, Stachurski J. Suicide attempts among children and adolescents admitted to a Polish Emergency Department: Analysis of epidemiology, circumstances and methods of 154 cases. Adv Clin Exp Med. 2023;32(12):1377-1384. https://doi.org/10.17219/acem/162245

[16] Błaszczak, Jan. 2011. „Farmakokinetyka, metabolizm i hepatotoksyczność paracetamolu po narażeniu pojedynczym i łączonym z trichloroetylenem i N-acetylocysteiną”. http://www.wbc.poznan.pl/Content/220045/PDF/index.pdf. (Access: 3.01.2025)

[17] Dart RC, Mullins ME, Matoushek T, et al. Management of Acetaminophen Poisoning in the US and Canada: A Consensus Statement [published correction appears in JAMA Netw Open. 2023 Sep 5;6(9):e2337926. doi: 10.1001/jamanetworkopen.2023.37926]. JAMA Netw Open. 2023;6(8):e2327739. Published 2023 Aug 1. https://doi.org/10.1001/jamanetworkopen.2023.27739

[18] Chiew AL, Reith D, Pomerleau A, et al. Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand. Med J Aust. 2020;212(4):175-183. https://doi.org/10.5694/mja2.50428

[19] Kostowski W, Herman Z(red.). Pharmacology. PZWL 2010;1(2);225-228

[20] Panasiuk L, Król M, Szponar E, Szponar J. Acute poisoning. General Practice. 1st ed. PZWL. 2010;59-61

[21] Burchell B, Soars M, Monaghan G, Cassidy A, Smith D, Ethell B. Drug-mediated toxicity caused by genetic deficiency of UDP-glucuronosyltransferases. Toxicol Lett. 2000;112-113:333-340. https://doi.org/10.1016/s0378-4274(99)00209-x

[22] Prescott LF. Paracetamol: past, present, and future. Am J Ther. 2000;7:143-147.

[23] Zhou S, Chan E, Duan W, Huang M, Chen YZ. Drug bioactivation, covalent binding to target proteins and toxicity relevance. Drug Metab Rev. 2005;37(1):41-213. https://doi.org/10.1081/dmr-200028812

[24] Craig DG, Ford AC, Hayes PC, Simpson KJ. Systematic review: prognostic tests of paracetamol-induced acute liver failure. Aliment Pharmacol Ther. 2010;31(10):1064-1076. https://doi.org/10.1111/j.1365-2036.2010.04279.x

[25] Forrest JA, Clements JA, Prescott LF. Clinical pharmacokinetics of paracetamol. Clin Pharmacokinet. 1982;7(2):93-107. https://doi.org/10.2165/00003088-198207020-00001

[26] Hinz-Brylew N, Rajewski P. Acute paracetamol poisoning — three cases description Acute paracetamol poisoning— three cases description. Forum Medycyny Rodzinnej 2011;5(5):429–433

[27] Medscape - Drugs&Diseases / Emergency Medicine / Acetaminophen Toxicity Clinical Presentation https://emedicine.medscape.com/article/820200-clinical?form=fpf (Access: 3.01.2025)

[28] Prescott LF. Kinetics and metabolism of paracetamol and phenacetin. Br J Clin Pharmacol. 1980 Oct;10 Suppl 2(Suppl 2):291S-298S. doi: 10.1111/j.1365-2125.1980.tb01812.x. PMID: 7002186; PMCID: PMC1430174.

[29] Szczeklik A. Choroby wewnętrzne. 2010. Medycyna Praktyczna. 2010; 1017–1020, 2295–2296.

[30] Sen S, Mookerjee RP, Davies NA, Williams R, Jalan R. Review article: the molecular adsorbents recirculating system (MARS) in liver failure. Aliment Pharmacol Ther. 2002;16 Suppl 5:32-38. https://doi.org/10.1046/j.1365-2036.16.s5.5.x

[31] Prescott LF. Paracetamol, alcohol and the liver. Br J Clin Pharmacol. 2000;49(4):291-301. https://doi.org/10.1046/j.1365-2125.2000.00167.x

[32] Goldman-Mellor S, Allen K, Kaplan MS. Rural/Urban Disparities in Adolescent Nonfatal Suicidal Ideation and Suicide Attempt: A Population-Based Study. Suicide Life Threat Behav. 2018;48(6):709-719. https://doi.org/10.1111/sltb.12390

[33] Rosen ML, Rodman AM, Kasparek SW, et al. Promoting youth mental health during the COVID-19 pandemic: A longitudinal study. PLoS One. 2021;16(8):e0255294. Published 2021 Aug 11. https://doi.org/10.1371/journal.pone.0255294

[34] Kang S, Jeong Y, Park EH, Hwang SS. The Impact of Household Economic Deterioration Caused by the COVID-19 Pandemic and Socioeconomic Status on Suicidal Behaviors in Adolescents: A Cross-sectional Study Using 2020 Korea Youth Risk Behavior Web-based Survey Data. J Prev Med Public Health. 2022 Sep;55(5):455-463. https://doi.org/10.3961/jpmph.22.241

[35] Agostino H, Burstein B, Moubayed D, et al. Trends in the Incidence of New-Onset Anorexia Nervosa and Atypical Anorexia Nervosa Among Youth During the COVID-19 Pandemic in Canada. JAMA Netw Open. 2021;4(12):e2137395. Published 2021 Dec 1. https://doi.org/10.1001/jamanetworkopen.2021.37395

Downloads

  • PDF

Published

2025-02-10

How to Cite

1.
KUBICKA, Maria, POLAŃSKA, Paulina, GRUSZKA, Marta and ZAKROCKA, Martyna. Analysis of poisoning with OTC drugs for suicidal purposes among children and adolescents in Poland in the period 2012 - 2023: Paracetamol as the most frequently used substance in intentional poisonings. Journal of Education, Health and Sport. Online. 10 February 2025. Vol. 78, p. 57622. [Accessed 18 November 2025]. DOI 10.12775/JEHS.2025.78.57622.
  • ISO 690
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
Download Citation
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

Issue

Vol. 78 (2025)

Section

Medical Sciences

License

Copyright (c) 2025 Maria Kubicka, Paulina Polańska, Marta Gruszka, Martyna Zakrocka

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

Stats

Number of views and downloads: 596
Number of citations: 0

Search

Search

Browse

  • Browse Author Index
  • Issue archive

User

User

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians

Newsletter

Subscribe Unsubscribe

Tags

Search using one of provided tags:

suicide attempt, paracetamol, poisoning
Up

Akademicka Platforma Czasopism

Najlepsze czasopisma naukowe i akademickie w jednym miejscu

apcz.umk.pl

Partners

  • Akademia Ignatianum w Krakowie
  • Akademickie Towarzystwo Andragogiczne
  • Fundacja Copernicus na rzecz Rozwoju Badań Naukowych
  • Instytut Historii im. Tadeusza Manteuffla Polskiej Akademii Nauk
  • Instytut Kultur Śródziemnomorskich i Orientalnych PAN
  • Instytut Tomistyczny
  • Karmelitański Instytut Duchowości w Krakowie
  • Ministerstwo Kultury i Dziedzictwa Narodowego
  • Państwowa Akademia Nauk Stosowanych w Krośnie
  • Państwowa Akademia Nauk Stosowanych we Włocławku
  • Państwowa Wyższa Szkoła Zawodowa im. Stanisława Pigonia w Krośnie
  • Polska Fundacja Przemysłu Kosmicznego
  • Polskie Towarzystwo Ekonomiczne
  • Polskie Towarzystwo Ludoznawcze
  • Towarzystwo Miłośników Torunia
  • Towarzystwo Naukowe w Toruniu
  • Uniwersytet im. Adama Mickiewicza w Poznaniu
  • Uniwersytet Komisji Edukacji Narodowej w Krakowie
  • Uniwersytet Mikołaja Kopernika
  • Uniwersytet w Białymstoku
  • Uniwersytet Warszawski
  • Wojewódzka Biblioteka Publiczna - Książnica Kopernikańska
  • Wyższe Seminarium Duchowne w Pelplinie / Wydawnictwo Diecezjalne „Bernardinum" w Pelplinie

© 2021- Nicolaus Copernicus University Accessibility statement Shop