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Journal of Education, Health and Sport

Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions
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  4. Medical Sciences

Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions

Authors

  • Magdalena Rosa-Bończak Fryderyk Chopin University Clinical Hospital in Rzeszow, Fryderyk Chopin Street 2, 35-055 Rzeszow https://orcid.org/0009-0005-7266-6930
  • Patrycja Marta Fryderyk Chopin University Clinical Hospital in Rzeszow, Fryderyk Chopin Street 2, 35-055 Rzeszow https://orcid.org/0009-0009-6972-8140
  • Filip Maciej Huzarski https://orcid.org/0009-0002-3773-5388
  • Klaudia Anna Pawełek https://orcid.org/0009-0005-6166-6396
  • Gabriela Monika Ferfecka https://orcid.org/0009-0001-2908-9171
  • Agata Ossolińska Fryderyk Chopin University Clinical Hospital in Rzeszow, Fryderyk Chopin Street 2, 35-055 Rzeszow https://orcid.org/0009-0005-4941-7039
  • Natalia Morawiecka https://orcid.org/0009-0006-6043-8188
  • Lucyna Stolarska https://orcid.org/0009-0009-0480-304X
  • Oliver Carlton https://orcid.org/0009-0001-1506-626X
  • Weronika Kłosowicz Fryderyk Chopin University Clinical Hospital in Rzeszow, Fryderyk Chopin Street 2, 35-055 Rzeszow https://orcid.org/0009-0006-1452-7411

DOI:

https://doi.org/10.12775/JEHS.2025.78.57458

Keywords

insomia, reproductive health, hormonal disorders, sleep hygiene, shift work

Abstract

Introduction

The role of sleep in maintaining the body's homeostasis has been the subject of an increasing number of scientific studies, with reproductive health also being dependent on it. Reduced fertility, resulting from the deterioration of reproductive cell quality due to hormonal imbalances, may be a consequence of sleep deprivation. Chronic stress, obesity, and other factors accompanying sleep disturbances can impair the functioning of hormonal axes, ultimately leading to oxidative stress—a metabolic basis for fertility issues. The aim of this study is to analyze the impact of sleep disorders on reproductive health, focusing on the mechanisms, clinical consequences, and potential therapeutic interventions.

 

 

Materials and Methods

This article is based on an analysis of scientific literature concerning the impact of sleep disturbances on reproductive health, utilizing data from databases such as PubMed, Frontiers, and Google Scholar. Studies in fields such as endocrinology, sleep medicine, gynecology, andrology, and psychology were included. Both primary research and systematic reviews, as well as meta-analyses with high methodological quality and statistical significance, were analyzed. This approach provides a comprehensive overview of the relationship between sleep and fertility, considering both biological and psychological mechanisms.

Conclusions

In both sexes, sleep disturbances can lead to reproductive health problems due to hormonal imbalances, resulting in the deterioration of reproductive cell quality. Factors such as obesity, stress, or shift work further increase the risk of infertility. Recent findings emphasize that mindfulness techniques, cognitive-behavioral therapy, improved sleep hygiene, and even melatonin supplementation may contribute to the success of infertility treatments, including assisted reproductive techniques. It is crucial to raise public awareness about the role of sleep and stress in fertility issues. However, further research is needed to better understand these relationships and develop personalized therapies.

References

1. Zhong O, Liao B, Wang J, Liu K, Lei X and Hu L. Effects of Sleep Disorders and Circadian Rhythm Changes on Male Reproductive Health: A Systematic Review and Meta-analysis. Front. Physiol. 2022; 13:913369; doi: 10.3389/fphys.2022.913369

2. Lateef OM, Akintubosun MO. Sleep and Reproductive Health. Journal of Circadian Rhythms. 2022; 18(1): 1, pp. 1–11; doi: 10.5334/jcr.190

3. Reschini M, Buoli M, Facchin F. et al. Women’s quality of sleep and in vitro fertilization success. Sci Rep. 2022; t.12, 17477; https://doi.org/10.1038/s41598-022-22534-0

4. Du, C. Q., Zhang, D. X., Chen, J., He, Q. F., & Lin, W. Q. Men’s Sleep Quality and Assisted Reproductive Technology Outcomes in Couples Referred to a Fertility Clinic: A Chinese Cohort Study. Nature and Science of Sleep. 2022, t.14, p. 557–566; https://doi.org/10.2147/NSS.S353131

5. Krajewska O, Skrypnik K, Kręgielska-Narożna M, Suliburska J, Bogdański P. Effect of length and quality of sleep on anthropometric and metabolic parameters, general physical and mental health. Via Medica Journals. 2017, t. 8, nr 2, p. 47–54; https://journals.viamedica.pl/forum_zaburzen_metabolicznych/article/view/54254 (09.12.2024r).

6. Dağ ZÖ, Dilbaz B. Impact of obesity on infertility in women. J Turk Ger Gynecol Assoc. 2015;16(2):111-117. Published 2015 Jun 1; doi:10.5152/jtgga.2015.15232

7. Gambineri A, Laudisio D, Marocco C, et al. Female infertility: which role for obesity? Int J Obes Suppl. 2019;9(1):65-72; doi:10.1038/s41367-019-0009-1

8. Katib A. Mechanisms linking obesity to male infertility. Cent European J Urol. 2015;68(1):79-85; doi:10.5173/ceju.2015.01.435

9. Kang W, Jang KH, Lim HM., et al. The menstrual cycle associated with insomnia in newly employed nurses performing shift work: a 12-month follow-up study. Int Arch Occup Environ Health. 2019, p. 227–235; https://doi.org/10.1007/s00420-018-1371-y

10. Caetano G, Bozinovic I, Dupont C, Léger D, Lévy R, Sermondade N. Impact of sleep on female and male reproductive functions: a systematic review. Fertil Steril. 2021;115(3):715-731; doi:10.1016/j.fertnstert.2020.08.1429

11. Nitsche K, Ehrmann D. A., Obstructive sleep apnea and metabolic dysfunction in polycystic ovary syndrome, Best Practice & Research Clinical Endocrinology & Metabolism. 2010, Volume 24, Issue 5, p. 717-730, ISSN 1521-690X; https://doi.org/10.1016/j.beem.2010.08.001.

12. Baumgartner A, Dietzel M, Saletu B, Wolf R, Campos-Barros A, Gräf K-J, Kürten I, Mannsmann U, Influence of partial sleep deprivation on the secretion of thyrotropin, thyroid hormones, growth hormone, prolactin, luteinizing hormone, follicle stimulating hormone, and estradiol in healthy young women, Psychiatry Research. 1993, Volume 48, Issue 2, p. 153-178,, https://doi.org/10.1016/0165-1781(93)90039-J.

13. Alvarenga T. A, Hirotsu C, Mazaro-Costa R, Tufik S, Andersen M.L, Impairment of male reproductive function after sleep deprivation, Fertility and Sterility. 2015, Volume 103, Issue 5, p. 1355-1362.el; https://doi.org/10.1016/j.fertnstert.2015.02.002.

14. Pajėdienė E, Urbonavičiūtė V, Ramanauskaitė V ,Strazdauskas L Stefani A, Sex Differences in Insomnia and Circadian Rhythm Disorders: A Systematic Review, Medicina 2024, 60, 474; https://doi.org/10.3390/medicina60030474

15. Suchecki D, Lobo L, Hipólide D, Tufik S, Increased ACTH and corticosterone secretion induced by different methods of paradoxical sleep deprivation, Journal of sleep research, 21 July 2004; https://doi.org/10.1046/j.1365-2869.1998.00122.x

16. Leproult R, Van Cauter E. Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men. JAMA. 2011; 305(21):2173–2174; doi:10.1001/jama.2011.710

17. Corona, G., Maggi, M. The role of testosterone in male sexual function. Rev Endocr Metab Disord 23. 2022, 1159–1172; https://doi.org/10.1007/s11154-022-09748-3

18. Li C, Zhou X, Melatonin and male reproduction, Clinica Chimica Acta. 2015, Volume 446, p. 175-180; https://doi.org/10.1016/j.cca.2015.04.029.

19. Morssinkhof M.W.L, van Wylick D.W, Priester-Vink S, van der Werf Y.D, den Heijer M, van den Heuvel O.A, Broekman B.F.P. Associations between sex hormones, sleep problems and depression: A systematic review, Neuroscience & Biobehavioral Reviews. 2020, Volume 118, p. 669-680, https://doi.org/10.1016/j.neubiorev.2020.08.006.

20. Wójcik A, The impact of sleep on metabolic health, Practical Medicine, https://praktycznamedycyna.pl/leczenie/wplyw-snu-na-zdrowie-metaboliczne/ (09.12.2024)

21. Yuan An, Zhuoran Wang, Hongping Ji, Yajuan Zhang, Kun Wu, Pituitary-adrenal and sympathetic nervous system responses to psychiatric disorders in women undergoing in vitro fertilization treatment, Fertility and Sterility. 2011, Volume 96, Issue 2, p. 404-408; https://doi.org/10.1016/j.fertnstert.2011.05.092.

22. Smeenk J.M.J, Verhaak C.M, Vingerhoets A.J.J.M, Sweep C.G.J,.Merkus J.M.W.M, Willemsen S.J, van Minnen A, Straatman H, Braat D.D.M, Stress and outcome success in IVF: the role of self-reports and endocrine variables, Human Reproduction. 2005, Volume 20, Issue 4, p. 991–996; https://doi.org/10.1093/humrep/deh739

23. Cho J. W, Duffy J.F, Sleep, Sleep Disorders, and Sexual Dysfunction, he World Journal of Men's Health. 2019; 37(3): 261-275; https://doi.org/10.5534/wjmh.180045

24. Chau Y.M, West S, Mapedzahama V, Night Work and the Reproductive Health of Women: An Integrated Literature Review, Journal of Midwifery & Women's Health, 17 October 2013, p. 113-126; https://doi.org/10.1111/jmwh.12052

25. McDowall K, Murphy E, Anderson K, The impact of shift work on sleep quality among nurses, Occupational Medicine. 2017, Volume 67, Issue 8, p. 621–625; https://doi.org/10.1093/occmed/kqx152

26. https://www.nhshealthatwork.co.uk/, Access 12/12/2024.

27. Palmer KT, Bonzini M, Harris EC, et al. Occup Environ Med. 2013; 70:213–222; http://dx.doi.org/10.1136/oemed-2012-101032

28. Demirkol M.K,, Yıldırım A, Gıca S, Doğan N.T, Resim S, Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic. 12 May 2021; https://doi.org/10.1111/and.14116

29. Pastuszak A.W, Moonc Y.M, Scovella J, Badalc J, Lamba D.J, Linka R, Lipshultz L.I, Poor Sleep Quality Predicts Hypogonadal Symptoms and Sexual Dysfunction in Male Nonstandard Shift Workers, Urology. April 2017, Volume 102, p. 121-125; https://www.goldjournal.net/action/showCitFormats?doi=10.1016%2Fj.urology.2016.11.033&pii=S0090-4295%2816%2930906-2

30. Kohn TP, Pastuszak AW, Pickett SM, Kohn JR, Lipshultz LI. PD13-08 Shift work is associated with altered semen parameters in infertile men. Journal of Urology. April 2017; https://doi.org/10.1016/j.juro.2017.02.696

31. Rodriguez KM, Kohn TP, Kohn JR, et al. Shift Work Sleep Disorder and Night Shift Work Significantly Impair Erectile Function. J Sex Med. 2020; 17(9):1687-1693; doi:10.1016/j.jsxm.2020.06.009

32. Castleman MA, To the Many Health Hazards of Shift Work, Add Sex Problems. Shift-working men face risk of erection problems, women loss of erotic pleasure, Updated October 15, 2023; https://www.psychologytoday.com/; access 12.12.2024

33. Bahman, Maryam; Hajimehdipoor, Homa1; Afrakhteh, Maryam; Bioos, Soodabeh; Hashem-Dabaghian, Fataneh; Tansaz, Mojgan. The Importance of Sleep Hygiene in Polycystic Ovary Syndrome from the View of Iranian Traditional Medicine and Modern Medicine. International Journal of Preventive Medicine 9(1); p. 87; doi: 10.4103/ijpvm.IJPVM_352_16

34. Eryilmaz OG, Devran A, Sarikaya E, Aksakal FN, Mollamahmutoğlu L, Cicek N. Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems. J Assist Reprod Genet. 2011; 28(9):815-820; doi:10.1007/s10815-011-9604-y

35. Auld F, Maschauer E.L, Morrison I, Skene D.J, Riha R.L, Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders, Sleep Medicine Reviews, 2017, Volume 34, p. 10-22, ISSN 1087-0792; https://doi.org/10.1016/j.smrv.2016.06.005.

36. Koffel, E, Bramoweth, A.D. & Ulmer, C.S, Increasing access to and utilization of cognitive behavioral therapy for insomnia (CBT-I): a narrative review. J GEN INTERN MED 33. 2018, p. 955–962; https://doi.org/10.1007/s11606-018-4390-1

37. Galhardo A, Cunha M, Pinto-Gouveia J, Mindfulness-Based Program for Infertility: efficacy study, Fertility and Sterility. 2013, Volume 100, Issue 4, p. 1059-1067, ISSN 0015-0282; https://doi.org/10.1016/j.fertnstert.2013.05.036

38. Lie JD, Tu KN, Shen DD, Wong BM. Pharmacological Treatment of Insomnia. P T. 2015; 40(11):759-771.

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Published

2025-02-10

How to Cite

1.
ROSA-BOŃCZAK, Magdalena, MARTA, Patrycja, HUZARSKI, Filip Maciej, PAWEŁEK, Klaudia Anna, FERFECKA, Gabriela Monika, OSSOLIŃSKA, Agata, MORAWIECKA, Natalia, STOLARSKA, Lucyna, CARLTON, Oliver and KŁOSOWICZ, Weronika. Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions. Journal of Education, Health and Sport. Online. 10 February 2025. Vol. 78, p. 57458. [Accessed 23 December 2025]. DOI 10.12775/JEHS.2025.78.57458.
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Vol. 78 (2025)

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Copyright (c) 2025 Magdalena Rosa-Bończak, Patrycja Marta, Filip Maciej Huzarski, Klaudia Anna Pawełek, Gabriela Monika Ferfecka, Agata Ossolińska, Natalia Morawiecka, Lucyna Stolarska, Oliver Carlton, Weronika Kłosowicz

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