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Journal of Education, Health and Sport

The Influence of The Anabolic Steroid Usage on The Physical Health: A Review
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The Influence of The Anabolic Steroid Usage on The Physical Health: A Review

Authors

  • Jakub Chodkowski Specialist Regional Hospital in Ciechanów https://orcid.org/0009-0006-7097-4435
  • Filip Grabowski Specialist Regional Hospital in Ciechanów https://orcid.org/0009-0007-0466-2764
  • Natalia Rulewska Specialist Regional Hospital in Ciechanów https://orcid.org/0009-0008-4515-7403
  • Aleksandra Feruś Warsaw Southern Hospital https://orcid.org/0009-0000-3455-5096

DOI:

https://doi.org/10.12775/JEHS.2024.75.56384

Keywords

anabolic steroids, health effects, cardiovascular risk, endocrine diruption

Abstract

Introduction: Anabolic steroids are synthetic derivatives of testosterone commonly used to enhance athletic performance and physical appearance. Despite their popularity, their non-medical use is associated with significant health risks. This review aims to synthesize current knowledge on the impact of anabolic steroid use on physical health, emphasizing cardiovascular, hepatic, endocrine, and musculoskeletal systems, as well as broader systemic effects.

Materials and Methods: A systematic literature review was conducted using peer-reviewed articles from databases such as PubMed, Scopus, and Google Scholar published between 2000 and 2023. Studies were selected based on relevance, with particular focus on human clinical trials, observational studies, and meta-analyses. Keywords included "anabolic steroids," "health effects," "cardiovascular risk," and "endocrine disruption." 

Results: Anabolic steroid use is linked to increased cardiovascular risks, liver dysfunction, endocrine disturbances, and musculoskeletal injuries. Key effects include hypertension, hepatotoxicity, testosterone suppression, infertility, and tendon injuries. Psychological impacts such as aggression and mood changes were also observed.

Conclusions: Anabolic steroid use poses significant risks to multiple organ systems and overall health. Despite widespread awareness of these dangers, misuse persists, often driven by societal pressures and misinformation. Healthcare providers should prioritize prevention through education, early intervention, and support for individuals at risk. Future research should focus on long-term effects and effective strategies for harm reduction.

References

Sagoe D, Molde H, Andreassen CS, Torsheim T, Pallesen S. The global epidemiology of anabolic-androgenic steroid use: a meta-analysis and meta-regression analysis. Ann Epidemiol. 2014;24(5):383-398. doi:10.1016/j.annepidem.2014.01.009

Kanayama G, Hudson JI, Pope HG Jr. Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: a looming public health concern?. Drug Alcohol Depend. 2008;98(1-2):1-12. doi:10.1016/j.drugalcdep.2008.05.004

van de Ven K, Koenraadt R. Exploring the relationship between online buyers and sellers of image and performance enhancing drugs (IPEDs): Quality issues, trust and self-regulation. Int J Drug Policy. 2017;50:48-55. doi:10.1016/j.drugpo.2017.09.004

Baggish AL, Weiner RB, Kanayama G, et al. Cardiovascular Toxicity of Illicit Anabolic-Androgenic Steroid Use. Circulation. 2017;135(21):1991-2002. doi:10.1161/CIRCULATIONAHA.116.026945

Andrade RJ, Lucena MI, Fernández MC, et al. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period [published correction appears in Gastroenterology. 2005 Nov;129(5):1808]. Gastroenterology. 2005;129(2):512-521. doi:10.1016/j.gastro.2005.05.006

de Souza GL, Hallak J. Anabolic steroids and male infertility: a comprehensive review. BJU Int. 2011;108(11):1860-1865. doi:10.1111/j.1464-410X.2011.10131.x

Hartgens F, Kuipers H. Effects of androgenic-anabolic steroids in athletes. Sports Med. 2004;34(8):513-554. doi:10.2165/00007256-200434080-00003

Payne JR, Kotwinski PJ, Montgomery HE. Cardiac effects of anabolic steroids. Heart. 2004;90(5):473-475. doi:10.1136/hrt.2003.025783

Thiblin I, Petersson A. Pharmacoepidemiology of anabolic androgenic steroids: a review. Fundam Clin Pharmacol. 2005;19(1):27-44. doi:10.1111/j.1472-8206.2004.00298.x

Kicman AT. Pharmacology of anabolic steroids. Br J Pharmacol. 2008;154(3):502-521. doi:10.1038/bjp.2008.165

Vanberg P, Atar D. Androgenic anabolic steroid abuse and the cardiovascular system. Handb Exp Pharmacol. 2010;(195):411-457. doi:10.1007/978-3-540-79088-4_18

Kafrouni MI, Anders RA, Verma S. Hepatotoxicity associated with dietary supplements containing anabolic steroids. Clin Gastroenterol Hepatol. 2007;5(7):809-812. doi:10.1016/j.cgh.2007.02.036

Dukewich M, Stolz AA. Anabolic steroid-associated liver injury. Clin Liver Dis (Hoboken). 2024;23(1):e0196. Published 2024 Jun 12. doi:10.1097/CLD.0000000000000196

Martin NM, Abu Dayyeh BK, Chung RT. Anabolic steroid abuse causing recurrent hepatic adenomas and hemorrhage. World J Gastroenterol. 2008;14(28):4573-4575. doi:10.3748/wjg.14.4573

Rahnema CD, Lipshultz LI, Crosnoe LE, Kovac JR, Kim ED. Anabolic steroid-induced hypogonadism: diagnosis and treatment. Fertil Steril. 2014;101(5):1271-1279. doi:10.1016/j.fertnstert.2014.02.002

Tanner SM, Miller DW, Alongi C. Anabolic steroid use by adolescents: prevalence, motives, and knowledge of risks. Clin J Sport Med. 1995;5(2):108-115. doi:10.1097/00042752-199504000-00007

Alèn M, Rahkila P, Reinilä M, Vihko R. Androgenic-anabolic steroid effects on serum thyroid, pituitary and steroid hormones in athletes. Am J Sports Med. 1987;15(4):357-361. doi:10.1177/036354658701500411

Kanayama G, DeLuca J, Meehan WP 3rd, et al. Ruptured Tendons in Anabolic-Androgenic Steroid Users: A Cross-Sectional Cohort Study. Am J Sports Med. 2015;43(11):2638-2644. doi:10.1177/0363546515602010

Rogol AD, Clark PA, Roemmich JN. Growth and pubertal development in children and adolescents: effects of diet and physical activity. Am J Clin Nutr. 2000;72(2 Suppl):521S-8S. doi:10.1093/ajcn/72.2.521S

Sibai T, Morgan EF, Einhorn TA. Anabolic agents and bone quality. Clin Orthop Relat Res. 2011;469(8):2215-2224. doi:10.1007/s11999-010-1722-9

Kanayama G, Brower KJ, Wood RI, Hudson JI, Pope HG Jr. Treatment of anabolic-androgenic steroid dependence: Emerging evidence and its implications. Drug Alcohol Depend. 2010;109(1-3):6-13. doi:10.1016/j.drugalcdep.2010.01.011

Piacentino D, Kotzalidis GD, Del Casale A, et al. Anabolic-androgenic steroid use and psychopathology in athletes. A systematic review. Curr Neuropharmacol. 2015;13(1):101-121. doi:10.2174/1570159X13666141210222725

Ip EJ, Lu DH, Barnett MJ, Tenerowicz MJ, Vo JC, Perry PJ. Psychological and physical impact of anabolic-androgenic steroid dependence. Pharmacotherapy. 2012;32(10):910-919. doi:10.1002/j.1875-9114.2012.01123

Sagoe D, McVeigh J, Bjørnebekk A, Essilfie MS, Andreassen CS, Pallesen S. Polypharmacy among anabolic-androgenic steroid users: a descriptive metasynthesis. Subst Abuse Treat Prev Policy. 2015;10:12. Published 2015 Mar 15. doi:10.1186/s13011-015-0006-5

Calabrese LH, Kleiner SM, Barna BP, et al. The effects of anabolic steroids and strength training on the human immune response. Med Sci Sports Exerc. 1989;21(4):386-392.

Hughes TK, Fulep E, Juelich T, Smith EM, Stanton GJ. Modulation of immune responses by anabolic androgenic steroids. Int J Immunopharmacol. 1995;17(11):857-863. doi:10.1016/0192-0561(95)00078-x

Davani-Davari D, Karimzadeh I, Khalili H. The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: a systematic review. BMC Nephrol. 2019;20(1):198. Published 2019 May 31. doi:10.1186/s12882-019-1384-0

Parente Filho SLA, Gomes PEAC, Forte GA, et al. Kidney disease associated with androgenic-anabolic steroids and vitamin supplements abuse: Be aware!. Nefrologia (Engl Ed). 2020;40(1):26-31. doi:10.1016/j.nefro.2019.06.003

Wenbo Z, Yan Z. The Uses of Anabolic Androgenic Steroids Among Athletes; Its Positive and Negative Aspects- A Literature Review. J Multidiscip Healthc. 2023;16:4293-4305. Published 2023 Dec 29. doi:10.2147/JMDH.S439384

Furth G, Marroquin NA, Kirk J, et al. Cutaneous Manifestations of Anabolic-Androgenic Steroid Use in Bodybuilders and the Dermatologist's Role in Patient Care. JMIR Dermatol. 2023;6:e43020. Published 2023 Aug 3. doi:10.2196/43020

Strauss RH, Yesalis CE. Anabolic steroids in the athlete. Annu Rev Med. 1991;42:449-457. doi:10.1146/annurev.me.42.020191.002313

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Published

2024-12-07

How to Cite

1.
CHODKOWSKI, Jakub, GRABOWSKI, Filip, RULEWSKA, Natalia and FERUŚ, Aleksandra. The Influence of The Anabolic Steroid Usage on The Physical Health: A Review. Journal of Education, Health and Sport. Online. 7 December 2024. Vol. 75, p. 56384. [Accessed 7 July 2025]. DOI 10.12775/JEHS.2024.75.56384.
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Vol. 75 (2024)

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Medical Sciences

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Copyright (c) 2024 Jakub Chodkowski, Filip Grabowski, Natalia Rulewska, Aleksandra Feruś

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