Examining the Effects of Probiotics on Athletes: A Review
DOI:
https://doi.org/10.12775/JEHS.2024.75.56190Keywords
probiotics, gut microflora, probiotics in sport, human microbiome, athletic performance, diet supplementationAbstract
Introduction and Objective. Probiotics, defined as live microorganisms that provide health benefits when consumed in sufficient quantities, have gained attention in the sports community. The surge in popularity of long-distance athletic competitions such as marathons, triathlons, and cycling races has led to heightened rivalry and a rising curiosity in strategies to improve sports performance. Studies have suggested that probiotics could be a valuable aid for athletes looking to improve their well-being and overall progress.
Methods. A literature review was conducted using PubMed and Google Scholar with search terms like "probiotics", "gut microflora", "probiotics in sport", "human microbiome", "athletic performance", "human microbiome", “diet supplementation” and related variations. Articles published within the last five years were prioritized.
Brief description of the state of Knowledge. Probiotic supplementation has been shown to positively impact the health and performance of athletes, primarily through modulation of the microbiota-gut-brain axis. This review examines the influence of probiotic supplements on athletic performance, focusing on their effects on gut microbiota, immune support, mental health, anti-inflammatory properties, and overall performance enhancement.
Conclusions. Probiotics have been found to have numerous health benefits within the microbiota-gut-brain axis, making them an emerging area of research in athletes. The aim of this research is to understand the potential impacts on athletes experiencing health issues such as gastrointestinal symptoms, lowered immune system, mental disorders, excessive inflammation, or those looking to improve endurance and performance.
References
Ogunrinola GA, Oyewale JO, Oshamika OO, Olasehinde GI. The Human Microbiome and Its Impacts on Health. Int J Microbiol. 2020;2020:8045646. Published 2020 Jun 12. doi:10.1155/2020/8045646
Cresci GA, Bawden E. Gut Microbiome: What We Do and Don't Know. Nutr Clin Pract. 2015;30(6):734-746. doi:10.1177/0884533615609899
Hemarajata P, Versalovic J. Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Therap Adv Gastroenterol. 2013;6(1):39-51. doi:10.1177/1756283X12459294
David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559-563. doi:10.1038/nature12820
Hill C, Guarner F, Reid G, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014;11(8):506-514. doi:10.1038/nrgastro.2014.66
Fenster K, Freeburg B, Hollard C, Wong C, Rønhave Laursen R, Ouwehand AC. The Production and Delivery of Probiotics: A Review of a Practical Approach. Microorganisms. 2019;7(3):83. Published 2019 Mar 17. doi:10.3390/microorganisms7030083
You S, Ma Y, Yan B, et al. The promotion mechanism of prebiotics for probiotics: A review. Front Nutr. 2022;9:1000517. Published 2022 Oct 5. doi:10.3389/fnut.2022.1000517
Gibson GR, Hutkins R, Sanders ME, et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol. 2017;14(8):491-502. doi:10.1038/nrgastro.2017.75
Cunningham M, Azcarate-Peril MA, Barnard A, et al. Shaping the Future of Probiotics and Prebiotics. Trends Microbiol. 2021;29(8):667-685. doi:10.1016/j.tim.2021.01.003
Díaz-Jiménez J, Sánchez-Sánchez E, Ordoñez FJ, et al. Impact of Probiotics on the Performance of Endurance Athletes: A Systematic Review. Int J Environ Res Public Health. 2021;18(21):11576. Published 2021 Nov 4. doi:10.3390/ijerph182111576
Nichols, Andrew. (2007). Probiotics and athletic performance: A systematic review. Current sports medicine reports. 6. 269-73. 10.1007/s11932-007-0044-5.
Marttinen M, Ala-Jaakkola R, Laitila A, Lehtinen MJ. Gut Microbiota, Probiotics and Physical Performance in Athletes and Physically Active Individuals. Nutrients. 2020;12(10):2936. Published 2020 Sep 25. doi:10.3390/nu12102936
Miranda-Comas G, Petering RC, Zaman N, Chang R. Implications of the Gut Microbiome in Sports. Sports Health. 2022;14(6):894-898. doi:10.1177/19417381211060006
Simons SM, Kennedy RG. Gastrointestinal problems in runners. Curr Sports Med Rep. 2004;3(2):112-116. doi:10.1249/00149619-200404000-00011
Peters HP, Bos M, Seebregts L, et al. Gastrointestinal symptoms in long-distance runners, cyclists, and triathletes: prevalence, medication, and etiology. Am J Gastroenterol. 1999;94(6):1570-1581. doi:10.1111/j.1572-0241.1999.01147.x
Plaza-Diaz J, Ruiz-Ojeda FJ, Gil-Campos M, Gil A. Mechanisms of Action of Probiotics [published correction appears in Adv Nutr. 2020 Jul 1;11(4):1054. doi: 10.1093/advances/nmaa042]. Adv Nutr. 2019;10(suppl_1):S49-S66. doi:10.1093/advances/nmy063
Barkhidarian B, Roldos L, Iskandar MM, Saedisomeolia A, Kubow S. Probiotic Supplementation and Micronutrient Status in Healthy Subjects: A Systematic Review of Clinical Trials. Nutrients. 2021;13(9):3001. Published 2021 Aug 28. doi:10.3390/nu13093001
Mazziotta C, Tognon M, Martini F, Torreggiani E, Rotondo JC. Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health. Cells. 2023;12(1):184. Published 2023 Jan 2. doi:10.3390/cells12010184
Amdekar S, Dwivedi D, Roy P, Kushwah S, Singh V. Probiotics: multifarious oral vaccine against infectious traumas. FEMS Immunol Med Microbiol. 2010;58(3):299-306. doi:10.1111/j.1574-695X.2009.00630.x
Reid G, Bruce AW, Fraser N, Heinemann C, Owen J, Henning B. Oral probiotics can resolve urogenital infections. FEMS Immunol Med Microbiol. 2001;30(1):49-52. doi:10.1111/j.1574-695X.2001.tb01549.x
Van Hoang V, Ochi T, Kurata K, Arita Y, Ogasahara Y, Enomoto K. Nisin-induced expression of recombinant T cell epitopes of major Japanese cedar pollen allergens in Lactococcus lactis. Appl Microbiol Biotechnol. 2018;102(1):261-268. doi:10.1007/s00253-017-8579-8
Yeşilyurt N, Yılmaz B, Ağagündüz D, Capasso R. Involvement of Probiotics and Postbiotics in the Immune System Modulation. Biologics. 2021; 1(2):89-110. doi:10.3390/biologics1020006
Gleeson M, Nieman DC, Pedersen BK. Exercise, nutrition and immune function. J Sports Sci. 2004;22(1):115-125. doi:10.1080/0264041031000140590
Popova M, Molimard P, Courau S, et al. Beneficial effects of probiotics in upper respiratory tract infections and their mechanical actions to antagonize pathogens. J Appl Microbiol. 2012;113(6):1305-1318. doi:10.1111/j.1365-2672.2012.05394.x
Reardon CL, Hainline B, Aron CM, et al. Mental health in elite athletes: International Olympic Committee consensus statement (2019). Br J Sports Med. 2019;53(11):667-699. doi:10.1136/bjsports-2019-100715
Sabit H, Kassab A, Alaa D, et al. The Effect of Probiotic Supplementation on the Gut-Brain Axis in Psychiatric Patients. Curr Issues Mol Biol. 2023;45(5):4080-4099. Published 2023 May 6. doi:10.3390/cimb45050260
Bistas KG, Tabet JP. The Benefits of Prebiotics and Probiotics on Mental Health. Cureus. 2023;15(8):e43217. Published 2023 Aug 9. doi:10.7759/cureus.43217
Taylor AM, Holscher HD. A review of dietary and microbial connections to depression, anxiety, and stress. Nutr Neurosci. 2020;23(3):237-250. doi:10.1080/1028415X.2018.1493808
. Nazari M, Faghfoori Z, As’Habi A, Arab A, Hajianfar H. Probiotic consumption and inflammatory markers in athletes: a systematic review and meta-analysis. International Journal of Food Properties. 2020;23(1):1402-1415. doi:10.1080/10942912.2020.1807566
Moir HJ, Maciejczyk M, Maciejczyk M, Aidar FJ, Arazi H. Editorial: Exercise-induced oxidative stress and the role of antioxidants in sport and exercise. Front Sports Act Living. 2023;5:1269826. Published 2023 Aug 15. doi:10.3389/fspor.2023.1269826
Petersen LM, Bautista EJ, Nguyen H, et al. Community characteristics of the gut microbiomes of competitive cyclists. Microbiome. 2017;5(1):98. Published 2017 Aug 10. doi:10.1186/s40168-017-0320-4
Clarke SF, Murphy EF, O'Sullivan O, et al. Exercise and associated dietary extremes impact on gut microbial diversity. Gut. 2014;63(12):1913-1920. doi:10.1136/gutjnl-2013-306541
Scheiman J, Luber JM, Chavkin TA, et al. Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. Nat Med. 2019;25(7):1104-1109. doi:10.1038/s41591-019-0485-4
Shing CM, Peake JM, Lim CL, et al. Effects of probiotics supplementation on gastrointestinal permeability, inflammation and exercise performance in the heat. Eur J Appl Physiol. 2014;114(1):93-103. doi:10.1007/s00421-013-2748-y
Aykut MN, Erdoğan EN, Çelik MN, Gürbüz M. An Updated View of the Effect of Probiotic Supplement on Sports Performance: A Detailed Review. Curr Nutr Rep. 2024;13(2):251-263. doi:10.1007/s13668-024-00527-x
Mazur-Kurach P, Frączek B, Klimek AT. Does Multi-Strain Probiotic Supplementation Impact the Effort Capacity of Competitive Road Cyclists?. Int J Environ Res Public Health. 2022;19(19):12205. Published 2022 Sep 26. doi:10.3390/ijerph191912205
McFarland LV. Efficacy of Single-Strain Probiotics Versus Multi-Strain Mixtures: Systematic Review of Strain and Disease Specificity. Dig Dis Sci. 2021;66(3):694-704. doi:10.1007/s10620-020-06244-z
Wegierska AE, Charitos IA, Topi S, Potenza MA, Montagnani M, Santacroce L. The Connection Between Physical Exercise and Gut Microbiota: Implications for Competitive Sports Athletes. Sports Med. 2022;52(10):2355-2369. doi:10.1007/s40279-022-01696-x
Lin CL, Hsu YJ, Ho HH, et al. Bifidobacterium longum subsp. longum OLP-01 Supplementation during Endurance Running Training Improves Exercise Performance in Middle- and Long-Distance Runners: A Double-Blind Controlled Trial. Nutrients. 2020;12(7):1972. Published 2020 Jul 2. doi:10.3390/nu12071972
Rhayat L, Maresca M, Nicoletti C, et al. Effect of Bacillus subtilis Strains on Intestinal Barrier Function and Inflammatory Response. Front Immunol. 2019;10:564. Published 2019 Mar 29. doi:10.3389/fimmu.2019.00564
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Gustaw Błaszczyński, Agnieszka Nowotarska, Paweł Nojek, Wiktoria Pawlik, Mariusz Zimonczyk, Monika Zawół
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0
Stats
Number of views and downloads: 77
Number of citations: 0