Carbamazepine - hematologic effects of the use

Authors

  • Kamil Leis Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz
  • Ewelina Mazur Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz
  • Paweł Szyperski Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz
  • Tomasz Aleksiewicz Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz
  • Tomasz Jamrożek Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz
  • Katarzyna Lipa Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz
  • Przemysław Gałązka Department of General and Oncological Paediatric Surgery, Antoni Jurasz University Hospital No. 1 in Bydgoszcz, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz

Keywords

carbamazepine, thrombocytopenia, hypogammaglobulinemia

Abstract

Carbamazepine is an antiepileptic drug which exhibits a number of side effects, namely including a headache, abdominal pain, increased blood pressure, but also hematologic disorders. Thrombocytopenia, hypogammaglobulinemia, leukopenia, neutropenia, agranulocytosis, aplastic anemia, pure red cell aplasia, leukemia or eosinophilia with DRESS syndrome belong to the latter. There is a low incidence of carbamazepine pharmacotherapy related symptoms and their exact mechanisms of action are still unknown.

Author Biography

Przemysław Gałązka, Department of General and Oncological Paediatric Surgery, Antoni Jurasz University Hospital No. 1 in Bydgoszcz, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz

MD; Ph.D. Assistant in Department of General and Oncological Paediatric Surgery; Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 85-090 Bydgoszcz, Poland

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Published

2018-06-24

How to Cite

1.
LEIS, Kamil, MAZUR, Ewelina, SZYPERSKI, Paweł, ALEKSIEWICZ, Tomasz, JAMROŻEK, Tomasz, LIPA, Katarzyna and GAŁĄZKA, Przemysław. Carbamazepine - hematologic effects of the use. Journal of Education, Health and Sport. Online. 24 June 2018. Vol. 8, no. 8, pp. 51-60. [Accessed 20 May 2025].

Issue

Vol. 8 No. 8 (2018)

Section

Review Articles

License

The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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