Implications in dental treatment during the use of antiresorptive drugs - a literature review
DOI:
https://doi.org/10.12775/JEHS.2024.69.55356Keywords
antiresorptives, bisphosphonates, osteonecrosis of the jaw, MRONJAbstract
Introduction: Antiresorptive drugs such as bisphosphonates and denosumab are crucial for treating osteoporosis, metastatic bone disease, and hypercalcemia by inhibiting osteoclast function. They can lead to medication-related osteonecrosis of the jaw (MRONJ) following invasive dental procedures, requiring careful management to mitigate potential adverse effects.
Purpose of work: Synthesis of knowledge about the impact of taking antiresorptive drugs on aspects of dental treatment.
Materials and methods: Materials used in this study were found in the PubMed and Google Scholar database, using the following key words “antiresorptives”, “bisphosphonates”, “dental treatment”, “osteonecrosis of the jaw”
Summary: Antiresorptive drugs like bisphosphonates and denosumab are essential for managing osteoporosis and other bone diseases but pose challenges in dental care, notably with risks such as medication-related osteonecrosis of the jaw (MRONJ). These medications influence treatment strategies across orthodontics, implantology, periodontal therapy, and endodontics, necessitating careful management to balance therapeutic benefits with potential dental complications.
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