How to manage a dry socket?- review of the latest treatment methods
DOI:
https://doi.org/10.12775/JEHS.2024.69.55270Keywords
dry socket, alveolar osteitis, alveolitis sicca dolorosa, socket pain treatmentAbstract
Introduction
Alveolar osteitis is the most common postoperative complication of tooth extraction. This medical condition has been recognized for decades, however its treatment approach is diverse with varying outcome.
Aim of the study
The purpose of this review is to examine and discuss contemporary methods of treating dry socket. Through a synthesis of available studies, the paper aims to identify the most beneficial methods to deal with this post-extraction complication.
Materials and methods
An analysis of scientific articles available in Pubmed and Google Scholar databases was conducted. The study used publications from 2017 to 2024. The search process included the use of the following keywords: “dry socket”, “alveolar osteitis”, “alveolitis sicca dolorosa”, “socket pain treatment”.
Results
Thirty-five articles were selected and reviewed carefully and independently by all authors. The agents used in the treatment of dry socket were classified as: remedies, drugs and medications, blood products, and technologies. Each group of agents is described with a discussion of their therapeutic efficacy.
Summary
Dry socket is a common dental problem. Currently, non-invasive methods of treating this complication are preferred. Modern solutions can provide quick and effective therapy. The treatment should relieve discomfort and promote tissue regeneration. Despite various methods, there is still no clear opinion on the best way to treat dry socket.
References
M. Taberner-Vallverdú and others, ‘Previous Dry Socket as a Risk Factor for Alveolar Osteitis: A Nested Case-Control Study in Primary Healthcare Services’, Journal of Clinical and Experimental Dentistry, 2022, pp. e479–85, doi:10.4317/jced.59586.
Jason Tasoulas and others, ‘An Unusual Microscopic Pattern of Foreign Body Reaction as a Complication of Dry Socket Management’, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 125.5 (2018), pp. e118–23, doi:10.1016/j.oooo.2017.08.010.
Ahmad Salem Assari and others, ‘Effectiveness of Different Socket Dressing Materials on the Postoperative Pain Following Tooth Extraction: A Randomized Control Trial’, Journal of Medicine and Life, 15.8 (2022), pp. 1005–12, doi:10.25122/jml-2022-0140.
John Mamoun, ‘Dry Socket Etiology, Diagnosis, and Clinical Treatment Techniques’, Journal of the Korean Association of Oral and Maxillofacial Surgeons, 44.2 (2018), p. 52, doi:10.5125/jkaoms.2018.44.2.52.
Li-Hang Shen and others, ‘High-Throughput Sequencing Analysis of Microbial Profiles in the Dry Socket’, Journal of Oral and Maxillofacial Surgery, 77.8 (2019), pp. 1548–56, doi:10.1016/j.joms.2019.02.041.
Afifah Ayuni Hg, Syafruddin Ilyas, and Olivia Avriyanti Hanafiah, ‘The Effect of Snakehead Fish (Channa Striata) Extract on Dry Socket Wound Healing: TGF-Β1 Expression in Rats Model’, Bioscientia Medicina : Journal of Biomedicine and Translational Research, 8.7 (2024), pp. 4639–47, doi:10.37275/bsm.v8i7.1035.
Ali Idrees and others, ‘The Validity of Salvadoria Persica and Nigella Sativa in the Treatment of Dry Socket’, Revista Española de Cirugía Oral y Maxilofacial, 44 (2022), doi:10.20986/recom.2022.1368/2022.
Zafar Ali Khan, Namdeo Prabhu, Naseer Ahmed, Abhishek Lal, and others, ‘A Comparative Study on Alvogyl and a Mixture of Black Seed Oil and Powder for Alveolar Osteitis: A Randomized Double-Blind Controlled Clinical Trial’, ed. by Andrea Scribante, International Journal of Clinical Practice, 2022 (2022), pp. 1–8, doi:10.1155/2022/7756226.
Mohamad Alabdullah, Zafin Z Kara Beit, and Asaad Shehada, ‘Comparative Clinical Study of the Effect of Nigella Sativa Oil on Soft Tissue Healing and Inflammation Reduction Compared to Eugenol in the Context of Dry Socket’, Cureus, 2023, doi:10.7759/cureus.35375.
Arsalan Ansari and others, ‘A Study to Evaluate the Efficacy of Honey in the Management of Dry Socket’, Contemporary Clinical Dentistry, 10.1 (2019), p. 52, doi:10.4103/ccd.ccd_283_18.
Renan R. Da Costa and others, ‘Antimicrobial and Bone Repair Effects of Boric Acid in a Rat Model of Dry Socket (Alveolar Osteitis) Following Dental Extraction’, Journal of Trace Elements in Medicine and Biology, 76 (2023), p. 127118, doi:10.1016/j.jtemb.2022.127118.
Ana Henriques Mota and others, ‘Design and Evaluation of Novel Topical Formulation with Olive Oil as Natural Functional Active’, Pharmaceutical Development and Technology, 23.8 (2018), pp. 794–805, doi:10.1080/10837450.2017.1340951.
Zafar Ali Khan, Namdeo Prabhu, Naseer Ahmed, and Rakhi Issrani, ‘Comparison between Olive Oil and Nano-Bio Fusion Gel and Their Role in the Treatment of Alveolar Osteitis: A Double-Blind Randomized Trial’, Indian Journal of Pharmaceutical Education and Research, 57.2s (2023), pp. s315-s320., doi:10.5530/ijper.57.2s.36.
Yadav Amit and others, ‘A Comparative Study of Alveogyl and ZOE in Dry Socket Syndrome’, Journal of Dental and Medical Sciences, 18.9 (2019), pp. 68–75, doi:10.9790/0853-1809046875.
Dipsikha Acharya and others, ‘Comparison Between Neocone, Alvogyl And Zinc Oxide Eugenol Packing For The Treatment Of Dry Socket’, Journal of Pharmaceutical Negative Results, 13.7 (2022), doi:10.47750/pnr.2022.13.S07.104
Nishant Kumar Tewari and others, ‘Comparison between Neocone and Zinc Oxide Eugenol for Treatment of Dry Socket’, Journal of Advanced Medical and Dental Sciences Research, 7.12 (2019), doi:10.21276/jamdsr
Mosaad Khalifah, ‘Curettage versus Zinc Oxide Eugenol as a Treatment Modality in Patients with Dry Socket’, Egyptian Dental Journal, 67.1 (2021), pp. 235–39, doi:10.21608/edj.2020.48499.1322.
H. Cho and others, ‘Effectiveness of Irrigation with Chlorhexidine after Removal of Mandibular Third Molars: A Randomised Controlled Trial’, British Journal of Oral and Maxillofacial Surgery, 56.1 (2018), pp. 54–59, doi:10.1016/j.bjoms.2017.11.010.
Lm. Sáez-Alcaide and others, ‘Efficacy of a Topical Gel Containing Chitosan, Chlorhexidine, Allantoin and Dexpanthenol for Pain and Inflammation Control after Third Molar Surgery: A Randomized and Placebo-Controlled Clinical Trial’, Medicina Oral Patología Oral y Cirugia Bucal, 2020, pp. e644–51, doi:10.4317/medoral.23661.
Jakub Suchánek and others, ‘Hyaluronic Acid-Based Medical Device for Treatment of Alveolar Osteitis—Clinical Study’, International Journal of Environmental Research and Public Health, 16.19 (2019), p. 3698, doi:10.3390/ijerph16193698.
Martin Kapitán and others, ‘Initial Observation of Factors Interfering with the Treatment of Alveolar Osteitis Using Hyaluronic Acid with Octenidine—A Series of Case Reports’, Biomolecules, 11.8 (2021), p. 1157, doi:10.3390/biom11081157.
Nuttawut Supachawaroj, Teerasak Damrongrungruang, and Sucharat Limsitthichaikoon, ‘Formulation Development and Evaluation of Lidocaine Hydrochloride Loaded in Chitosan-Pectin-Hyaluronic Acid Polyelectrolyte Complex for Dry Socket Treatment’, Saudi Pharmaceutical Journal, 29.9 (2021), pp. 1070–81, doi:10.1016/j.jsps.2021.07.007.
Abdelaziz Abdullah, Mohamed Mohamed, and Mahmoud Abdallah, ‘Efficacy of Tranexamic Acid on The Incidence of Dry Socket Following Lower Third Molar Surgery’, Al-Azhar Assiut Dental Journal, 3.1 (2020), pp. 83–88, doi:10.21608/aadj.2020.92946.
Hiroki Otake and others, ‘Oxytetracycline-Hydrocortisone Ointment Reduces the Occurrence of Both Dry Socket and Post-Extraction Pain after Third Molar Extraction: An Observational Study’, ed. by Robert Jeenchen Chen, PLOS ONE, 16.7 (2021), p. e0254221, doi:10.1371/journal.pone.0254221.
A.T. Çebi, ‘Evaluation of the Effects of Intra-Alveolar Irrigation with Clindamycin, Rifampicin and Sterile Saline in Alveolar Osteitis Treatment’, Journal of Stomatology, Oral and Maxillofacial Surgery, 121.6 (2020), pp. 680–83, doi:10.1016/j.jormas.2020.01.004.
Patricia Verónica Aulestia-Viera and others, ‘Guaiacol/β-Cyclodextrin for Rapid Healing of Dry Socket: Antibacterial Activity, Cytotoxicity, and Bone Repair—an Animal Study’, Oral and Maxillofacial Surgery, 23.1 (2019), pp. 53–61, doi:10.1007/s10006-019-00747-4.
Aqsa Kamal, Basheer Salman, Noor Hayati Abdul Razak, and others, ‘The Efficacy of Concentrated Growth Factor in the Healing of Alveolar Osteitis: A Clinical Study’, International Journal of Dentistry, 2020 (2020), pp. 1–9, doi:10.1155/2020/9038629.
Aqsa Kamal, Basheer Salman, Noor Hayatie Abdul Razak, and others, ‘A Comparative Clinical Study between Concentrated Growth Factor and Low-Level Laser Therapy in the Management of Dry Socket’, European Journal of Dentistry, 14.04 (2020), pp. 613–20, doi:10.1055/s-0040-1714765.
E Yüce and N Kömerik, ‘Potential Effects of Advanced Platelet Rich Fibrin as a Wound-Healing Accelerator in the Management of Alveolar Osteitis: A Randomized Clinical Trial’, Nigerian Journal of Clinical Practice, 22.9 (2019), p. 1189, doi:10.4103/njcp.njcp_27_19.
Mp Keshini and others, ‘Assessment of Healing Using Alvogyl and Platelet Rich Fibrin in Patients with Dry Socket - An Evaluative Study’, Annals of Maxillofacial Surgery, 10.2 (2020), p. 320, doi:10.4103/ams.ams_259_19.
Amir Hossein Nejat and others, ‘Effect of Photobiomodulation on the Incidence of Alveolar Osteitis and Postoperative Pain Following Mandibular Third Molar Surgery: A Double‐Blind Randomized Clinical Trial’, Photochemistry and Photobiology, 97.5 (2021), pp. 1129–35, doi:10.1111/php.13457.
Shatha S. ALHarthi and others, ‘Photobiomodulation for Managing “Dry Socket”: A Randomised Controlled Trial’, International Dental Journal, 73.2 (2023), pp. 267–73, doi:10.1016/j.identj.2022.06.002.
Damla Torul, Mehmet Melih Omezli, and Tolunay Avci, ‘Investigation of the Clinical Efficacy of CGF and Ozone in the Management of Alveolar Osteitis: A Randomized Controlled Trial’, Clinical Oral Investigations, 27.8 (2023), pp. 4521–29, doi:10.1007/s00784-023-05074-3.
Jehona Ahmedi and others, ‘Comparison between Ozone and CHX Gel Application for Reduction of Pain and Incidence of Dry Socket after Lower Third Molar Removal’, Clinical and Experimental Dental Research, 9.1 (2023), pp. 75–81, doi:10.1002/cre2.675.
Aqsa Kamal, Basheer Salman, Noor Hayatie Ar, and others, ‘Management of Dry Socket with Low-Level Laser Therapy’, Clinical Oral Investigations, 25.3 (2021), pp. 1029–33, doi:10.1007/s00784-020-03393-3.
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Copyright (c) 2024 Laura Pacek, Aleksandra Wróbel, Aleksandra Dziewulska, Weronika Kiełt, Klaudia Kowalska, Julia Kozłowska, Gabriela Broniec, Aleksandra Kudła, Barbara Wajdowicz, Rozalia Czapiewska
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