The Traumatic brain injuries in sports - neurological aspects
DOI:
https://doi.org/10.12775/JEHS.2024.67.55042Keywords
Traumatic Brain Injury, Chronic Traumatic Encephalopathy, Biomarkers, Neuroprotection,, Sport-related TBIAbstract
Traumatic Brain Injury (TBI) was characterized as alternation in brain function or any other sign of brain pathology resulting from external force. Sport-related traumatic brain injury (SR-TBI) calculated as up to 20% of all TBA. Different diagnostic tools, such as CT scan or MRI, are utilized in clinical assessment of the patients, however there is a necessity of further investigation of new diagnostic methods such as biomarkers. A long-term repetitive brain injury can lead in consequence to a Chronic Traumatic Encephalopathy (CTE). Neuroprotection, treatment and rehabilitation play a crucial role in both prevention and recovery of TBI patients.
References
Capizzi A, Woo J, Verduzco-Gutierrez M. Traumatic Brain Injury: An Overview of Epidemiology, Pathophysiology, and Medical Management. Med Clin North Am. 2020;104(2):213-238. doi:10.1016/j.mcna.2019.11.001
Khellaf A, Khan DZ, Helmy A. Recent advances in traumatic brain injury. J Neurol. 2019;266(11):2878-2889. doi:10.1007/s00415-019-09541-4
Theadom A, Mahon S, Hume P, et al. Incidence of Sports-Related Traumatic Brain Injury of All Severities: A Systematic Review. Neuroepidemiology. 2020;54(2):192-199. doi:10.1159/000505424
Sussman ES, Pendharkar AV, Ho AL, Ghajar J. Mild traumatic brain injury and concussion: terminology and classification. Handb Clin Neurol. 2018;158:21-24. doi:10.1016/B978-0-444-63954-7.00003-3
Ling H, Hardy J, Zetterberg H. Neurological consequences of traumatic brain injuries in sports. Mol Cell Neurosci. 2015;66(Pt B):114-122. doi:10.1016/j.mcn.2015.03.012
Thapa K, Khan H, Singh TG, Kaur A. Traumatic Brain Injury: Mechanistic Insight on Pathophysiology and Potential Therapeutic Targets. J Mol Neurosci. 2021;71(9):1725-1742. doi:10.1007/s12031-021-01841-7
Hasan GM, Anwar S, Shamsi A, Sohal SS, Hassan MI. The neuroprotective potential of phytochemicals in traumatic brain injury: mechanistic insights and pharmacological implications. Front Pharmacol. 2024;14:1330098. Published 2024 Jan 4. doi:10.3389/fphar.2023.1330098 (7)
Smith LGF, Milliron E, Ho ML, et al. Advanced neuroimaging in traumatic brain injury: an overview [published correction appears in Neurosurg Focus. 2021 Jan;50(1):E22. doi: 10.3171/2020.11.FOCUS19652a]. Neurosurg Focus. 2019;47(6):E17. Published 2019 Dec 1. doi:10.3171/2019.9.FOCUS19652 (8)
Toth A. Magnetic Resonance Imaging Application in the Area of Mild and Acute Traumatic Brain Injury: Implications for Diagnostic Markers?. In: Kobeissy FH, ed. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects. Boca Raton (FL): CRC Press/Taylor & Francis; 2015.
Hu L, Yang S, Jin B, Wang C. Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review. Front Neurosci. 2022;16:872609. Published 2022 Apr 13. doi:10.3389/fnins.2022.872609
Donnelly RR, Ugbolue UC, Gao Y, Gu Y, Dutheil F, Baker JS. A Systematic Review and Meta-Analysis Investigating Head Trauma in Boxing. Clin J Sport Med. 2023;33(6):658-674. doi:10.1097/JSM.0000000000001195
Vella MA, Crandall ML, Patel MB. Acute Management of Traumatic Brain Injury. Surg Clin North Am. 2017;97(5):1015-1030. doi:10.1016/j.suc.2017.06.003
Wang KK, Yang Z, Zhu T, et al. An update on diagnostic and prognostic biomarkers for traumatic brain injury. Expert Rev Mol Diagn. 2018;18(2):165-180. doi:10.1080/14737159.2018.1428089
Visser K, Koggel M, Blaauw J, van der Horn HJ, Jacobs B, van der Naalt J. Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review. Neurosci Biobehav Rev. 2022;132:154-168. doi:10.1016/j.neubiorev.2021.11.036
Edalatfar M, Piri SM, Mehrabinejad MM, et al. Biofluid Biomarkers in Traumatic Brain Injury: A Systematic Scoping Review. Neurocrit Care. 2021;35(2):559-572. doi:10.1007/s12028-020-01173-1
G. Ohhashi, S. Tani, S. Murakami, M. Kamio, T. Abe, J. Ohtuki Problems in health management of professional boxers in Japan Br. J. Sports Med., 36 (2002), pp. 346-352
McKee, AC, Daneshvar, DH, Alvarez, VE i in. Neuropatologia sportu. Acta Neuropathol 127 , 29–51 (2014). https://doi.org/10.1007/s00401-013-1230-6
Kaj Blennow, John Hardy, Henrik Zetterberg, The Neuropathology and Neurobiology of Traumatic Brain Injury, Neuron, Volume 76, Issue 5, 2012, Pages 886-899, ISSN 0896-6273, https://doi.org/10.1016/j.neuron.2012.11.021.
Nitin Agarwal, MD MD, Rut Thakkar, Khoi Than, MD MD, FAANS FAANS. Traumatic brain injury - causes, symptoms and treatments. AANS. [ Oct; 2022 ]. 2020. https://www.aans.org/Patients/Neurosurgical-Conditions-and-Treatments/Traumatic-Brain-Injury
Bieniek KF, Cairns NJ, Dams-O’Connor K, et al. The second NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. Acta Neuropathol. 2021;141(3):375-394.
Pierre K, Molina V, Shukla S, et al. Chronic traumatic encephalopathy: Diagnostic updates and advances. Cureus. 2023;15(2) . doi:10.7759/cureus.35219.
Organization WH. Rehabilitation in health systems Geneva: World Health Organization. 2017.
Marklund N, Bellander BM, Godbolt AK, Levin H, McCrory P, Thelin EP. Treatments and rehabilitation in the acute and chronic state of traumatic brain injury. J Intern Med. 2019;285(6):608-623. doi:10.1111/joim.12900
Clayton E, Kinley-Cooper SK, Weber RA, Adkins DL. Brain stimulation: Neuromodulation as a potential treatment for motor recovery following traumatic brain injury. Brain Res. 2016;1640(Pt A):130-138. doi:10.1016/j.brainres.2016.01.056
Chollet F, Tardy J, Albucher JF, et al. Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial [published correction appears in Lancet Neurol. 2011 Mar;10(3):205]. Lancet Neurol. 2011;10(2):123-130. doi:10.1016/S1474-4422(10)70314-8
Nasrallah HA, Chen AT. Multiple neurotoxic effects of haloperidol resulting in neuronal death. Ann Clin Psychiatry. 2017;29(3):195-202.
Resquín F, Gonzalez-Vargas J, Ibáñez J, et al. Adaptive hybrid robotic system for rehabilitation of reaching movement after a brain injury: a usability study. J Neuroeng Rehabil. 2017;14(1):104. Published 2017 Oct 12. doi:10.1186/s12984-017-0312-4
Kalra S, Malik R, Singh G, et al. Pathogenesis and management of traumatic brain injury (TBI): role of neuroinflammation and anti-inflammatory drugs. Inflammopharmacology. 2022;30(4):1153-1166. doi:10.1007/s10787-022-01017-8
Karakaya E, Oleinik N, Edwards J, et al. p17/C18-ceramide-mediated mitophagy is an endogenous neuroprotective response in preclinical and clinical brain injury. PNAS Nexus. 2024;3(2):pgae018. Published 2024 Feb 7. doi:10.1093/pnasnexus/pgae018
Lee DC, Vali K, Baldwin SR, et al. Dietary Supplementation With the Ketogenic Diet Metabolite Beta-Hydroxybutyrate Ameliorates Post-TBI Aggression in Young-Adult Male Drosophila. Front Neurosci. 2019;13:1140. Published 2019 Oct 30. doi:10.3389/fnins.2019.01140
Dolan E, Gualano B, Rawson ES. Beyond muscle: the effects of creatine supplementation on brain creatine, cognitive processing, and traumatic brain injury. Eur J Sport Sci. 2019;19(1):1-14. doi:10.1080/17461391.2018.1500644
Forbes SC, Cordingley DM, Cornish SM, et al. Effects of Creatine Supplementation on Brain Function and Health. Nutrients. 2022;14(5):921. Published 2022 Feb 22. doi:10.3390/nu14050921
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Copyright (c) 2024 Adrianna Marta Paziewska, Karolina Jurasz, Radosław Cymer, Ewa Rzeska, Michał Rogulski
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